Relationship between stroke onset timing and clinical outcomes in ischemic and hemorrhagic strokes: a systematic review. [PDF]
Heidari P +8 more
europepmc +1 more source
Cell‐Free DNA‐Based Theranostics for Inflammatory Disorders
Summary on the dual potential of cfDNA as biomarkers and therapeutic targets for inflammatory disorders. Figure was created with BioRender.com. ABSTRACT Inflammatory disorders are characterized by immune‐mediated inflammatory cascades that can affect multiple organs.
Jiatong Li +7 more
wiley +1 more source
The systematic use of cost-effectiveness criteria to inform decisions about the removal of items from publicly-financed 'benefits packages'. A report commissioned by the Department of Health and prepared by the London School of Hygiene and Tropical Medicine [PDF]
Ettelt, S, Mays, N, Nolte, E, Thomson, S
core
Migrasomes in Ischemic Stroke: Molecular Landscape and Pathophysiological Impact
Multi‐omics profiling of stroke patients exposes systemic molecular fingerprints of immune activation, oxidative stress and metabolic collapse. Complement and coagulation cascade, and cholesterol metabolism emerge as shared functional hallmarks of plasma migrasomes in stroke patients and migrasomes isolated from experimental stroke mice.
Huifen Zhou +16 more
wiley +1 more source
Optimizing Fluid Resuscitation Strategies: A Network Meta-analysis of Effectiveness and Safety for Hemorrhagic Shock Patients in Emergency Settings. [PDF]
Aldian FM +8 more
europepmc +1 more source
In hypoxic microenvironment, WNT5A is predominantly secreted by tumor‐associated macrophages. Hypoxia‐induced WTAP mediates ROR1 stability by m6A modifications in a HuR‐dependent manner in Glioma stem cells (GSCs). WNT5A activates the WNT pathway via ROR1 binding on GSCs, driving glioma‐derived endothelial cells (GDECs) differentiation.
Xiaoyong Chen +15 more
wiley +1 more source
To address multidrug‐resistant urinary tract infections (MDR‐UTIs), we developed Cu‐ZIF8‐Ru nanozyme featuring an asymmetric Cu─N─Ru catalytic site. This unique structure enhances multienzyme‐mimetic activity, eradicating resistant bacteria by inducing a cuproptosis‐like death pathway through intracellular Cu2+ accumulation and energy depletion.
Guanlin Li +9 more
wiley +1 more source
Angina Bullosa Hemorrhagica: A Rare Case Involving the Ventral Tongue. [PDF]
Khajehzadeh F.
europepmc +1 more source

