Results 251 to 260 of about 122,147 (327)

Advantages of Exome Sequencing Over Panel Testing for Individuals With a Seizure Indication

Annals of the Child Neurology Society, EarlyView.
ABSTRACT Objective Our aim was to investigate the advantages of exome sequencing versus panel testing for patients with unexplained seizures. Methods We reviewed the diagnostic outcomes of exome sequencing by a commercial genetics laboratory for more than 16 000 individuals with a clinical history of seizures or suspected seizures.
Michelle M. Morrow, Elizabeth Butler, Melanie P. Napier, Lindsay Havens‐Dyer, Annabelle Tuttle, Patricia C. Lopes, Britt A. Johnson, Paul Kruszka, Kirsty McWalter   +8 more
wiley   +1 more source

Fatal Flaw in the Folate Pathway: Methotrexate-Bactrim Interaction, Misleading Levels, and a Cautionary Case. [PDF]

Cureus
Pathak S.
europepmc   +1 more source

Fetal Pain Perception: Legislative Assertions and Developmental Neuroscience

Annals of the Child Neurology Society, EarlyView.
ABSTRACT Background Pain perception is a conscious experience, but neither pain nor consciousness is defined in the developing human fetus. Emergent consciousness may be regarded as a phenomenon that ultimately arises from an essential minimum of functional neuronal connectivity. Proposed U.S.
William D. Graf, Timothy M. Crombleholme, Leon G. Epstein, Dawn Gano, Phillip L. Pearl, Timothy V. Salomons, Mark S. Scher, Elise Turk, Klaus‐Peter Zimmer, Harvey B. Sarnat   +9 more
wiley   +1 more source

Rapid surgical intervention for acute spinal subdural hematoma triggered by ruptured spinal dural arteriovenous fistula: illustrative case. [PDF]

J Neurosurg Case Lessons
Naeem A, Mazza F, Shamisa A.
europepmc   +1 more source

A Phase 1, Randomized, Open‐Label, Parallel Group Study to Evaluate the Relative Bioavailability and Safety of Subcutaneous Bepirovirsen when Delivered from a Vial or Prefilled Syringe Fitted with a Safety Syringe Device in Healthy Adult Participants

Clinical Pharmacology in Drug Development, EarlyView.
Abstract Bepirovirsen, an antisense oligonucleotide in development for the treatment of chronic hepatitis B virus (HBV) infection, is administered from glass vials as a subcutaneous (SC) injection by healthcare professionals (HCPs). A ready‐to‐use prefilled syringe (PFS) assembled with a safety syringe device (SSD) has been developed to make ...
Amir S. Youssef, Poonam Shah, Maxwell Hu, Helene Plein, Abhishek Roy, Ravi Sharma, Sarah Mole, Magdalena Blazejczyk, Wendy Cross, Brian Spears, Samuel Pak, Rejbinder Kaur, Robert Elston, Dickens Theodore, Marjan Hezareh, Ahmed Nader   +15 more
wiley   +1 more source

Early brain-heart health manager-led multidimensional rehabilitation improves functional and psychosocial outcomes in hemorrhagic stroke: a retrospective cohort study. [PDF]

Front Neurol
Shi Y, Yan L, Yang M.
europepmc   +1 more source

Cardiovascular Risk of Romosozumab vs. Teriparatide: A Cohort Study Using Japan’s National Claims Database

Clinical Pharmacology &Therapeutics, EarlyView.
Disproportionality analyses suggested a cardiovascular risk signal for romosozumab, while statistically significant associations were not found in the real‐world database studies. Therefore, a larger comparative study was necessary to examine this signal.
Hotaka Maruyama, Eiko Iwasa, Shinya Watanabe, Tomoaki Hasegawa, Kazuhiro Kajiyama, Taihei Tanaka   +5 more
wiley   +1 more source

The Associations Between Vegetarian and Vegan Diets and Orthorexia Nervosa Symptoms in Adults: A Systematic Review and Meta‐Analysis

International Journal of Eating Disorders, EarlyView.
ABSTRACT Objective To synthesize the evidence on the associations between vegetarian and/or vegan diets (VVDs) and symptoms of orthorexia nervosa (ON) compared with omnivorous diets in the adult population. Method Following the Preferred Reporting Items for Systematic Reviews and Meta‐Analyses (PRISMA) and the Meta‐analyses of Observational Studies in ...
Valentina Díaz‐Goñi, Bruno Bizzozero‐Peroni, María Eugenia Visier‐Alfonso, Estela Jiménez‐López, Rubén Fernández‐Rodríguez, José Francisco López‐Gil, Tomás Olivo Martins‐de‐Passos, Alberto Durán González, Vicente Martínez‐Vizcaíno, Arthur Eumann Mesas   +9 more
wiley   +1 more source

Correction: Damoctocog Alfa Pegol, a PEGylated B-domain Deleted Recombinant Extended Half-life Factor VIII for the Treatment of Hemophilia A: A Product Review

Drugs in R&D
Mark T. Reding, Shadan Lalezari, Gili Kenet, Giovanni Di Minno, Jonathan Ducore, Alexander Solms, Anita Shah, Pål André Holme, Lone H. Poulsen, Karina Meijer, Mindy Simpson, Maria Elisa Mancuso   +11 more
doaj   +1 more source

Macrophage activation syndrome in a child with varicella: a case report. [PDF]

J Med Case Rep
Mateiko H, Synoverska O, Matvisiv M, Vovk Z, Horbal N.   +4 more
europepmc   +1 more source