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The pathogenesis of Ebola hemorrhagic fever

Trends in Microbiology, 2001
Ebola virus causes lethal hemorrhagic disease in humans, yet there are still no satisfactory biological explanations to account for its extreme virulence. This review focuses on recent findings relevant to understanding the pathogenesis of Ebola virus infection and developing vaccines and effective therapy.
Ayato Takada, Yoshihiro Kawaoka
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Lassa hemorrhagic fever model using new generalized Caputo-type fractional derivative operator

Advances in Complex Systems, 2021
In some of the previous decades, we have observed that mathematical modeling has become one of the most interesting research fields and has attracted many researchers.
Pushpendra Kumar   +3 more
semanticscholar   +1 more source

A Comparative Analysis of the Genetic Relationships Between the Pathogens of Ebola Hemorrhagic Fever, Marburg Virus, HIV, Hepatitis A, Hepatitis B, Hepatitis C, Hepatitis D, and Hepatitis E

, 2015
Ebola is a public health problem and a global monster currently ravaging many nations of the world especially West Africa. Ebola viruses are highly pathogenic, exotic agents that can cause severe hemorrhagic fever disease in human and/or nonhuman ...
Souilmi Yassine
semanticscholar   +1 more source

Ebola Hemorrhagic Fever: Tandala, Zaire, 1977-1978

Journal of Infectious Diseases, 1980
Ebola virus was recovered from a nine-year-old girl who died of acute hemorrhagic fever in June 1977 at Tandala Hospital in northwestern Zaire, in the first reported recognized case of this disease since the discovery epidemics of 1976 in Zaire and Sudan.
Karl M. Johnson   +11 more
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Other viral bioweapons: Ebola and Marburg hemorrhagic fever

Dermatologic Clinics, 2004
The term viral hemorrhagic fever refers to a clinical syndrome characterized by acute onset of fever accompanied by nonspecific findings of malaise, prostration, diarrhea,and headache. Patients frequently show signs of increased vascular permeability, and many develop bleeding diatheses.
Michelle R Salvaggio   +2 more
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Ebola virus: The role of macrophages and dendritic cells in the pathogenesis of Ebola hemorrhagic fever

The International Journal of Biochemistry & Cell Biology, 2005
Ebola hemorrhagic fever is a severe viral infection characterized by fever, shock and coagulation defects. Recent studies in macaques show that major features of illness are caused by effects of viral replication on macrophages and dendritic cells.
Mike Bray, Thomas W. Geisbert
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Ebola hemorrhagic fever: a paradigm of multiorgan dysfunction

Journal of Organ Dysfunction, 2005
Ebola virus (EBOV) is a filamentous negative-strand RNA virus with a glycoprotein envelope and comprises four species, Zaire, Sudan, Ivory Coast and Reston. It is a highly lethal pathogen for humans as well as non-human primates, and has been responsible for numerous African epidemics of viral hemorrhagic fever over the past 29 years.
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Comparative Pathogenesis of Crimean-Congo Hemorrhagic Fever and Ebola Hemorrhagic Fever

2007
Crimean-Congo hemorrhagic fever (CCHF) virus has been called “the Asian Ebola virus” – an epithet that recognizes the close clinical resemblance of CCHF and Ebola hemorrhagic fever (EHF), and also suggests that the two illnesses share similar underlying mechanisms [38]. CCHF and EHF both present difficult challenges to pathophysiology research, because
openaire   +2 more sources

Firsthand Clinical Observations of Hemorrhagic Manifestations in Ebola Hemorrhagic Fever in Zaire

Clinical Infectious Diseases, 1989
About 5 weeks after the beginning of the outbreak of Ebola virus fever in Yambuku, Zaire, several acute cases of the disease were observed. All of those affected had the following common signs and symptoms: sudden onset of high fever, with chills, headache, myalgia, anorexia, nausea, abdominal pain, sore throat, expressionless face, and profound ...
openaire   +3 more sources

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