Results 101 to 110 of about 35,523 (277)

Meningococcal Serogroup Y Meningitis Reveals Inborn Factor B Deficiency

European Journal of Immunology, Volume 56, Issue 2, February 2026.
We report a novel case of complete complement Factor B deficiency revealed by invasive meningococcal disease. Using combined functional and genetic analyses, we demonstrate that loss of Factor B abolishes alternative pathway activity despite detectable protein levels. These findings provide a mechanistic framework relevant to complement diagnostics and
Camille Bougeard, Eléonore Eskander, Paula Vieira Martins, Joan Bitan, Julia Roquigny, Christèle Kyheng, Tamazoust Guiddir, Véronique Frémeaux‐Bacchi, Cécile Gonnin, Carine ElSissy   +9 more
wiley   +1 more source

Acute hemorrhagic edema of young children: a concise narrative review [PDF]

, 2018
Acute hemorrhagic edema of young children is an uncommon but likely underestimated cutaneous leukocytoclastic vasculitis. The condition typically affects infants 6-24months of age with a history of recent respiratory illness with or without course of ...
Bettinelli, Alberto, Bianchetti, Mario, Fiore, Elisabetta, Garzoni, Luca, Rizzi, Mattia, Simonetti, Giacomo   +5 more
core  

Analysis of misdiagnosed cases of hemorrhagic fever with renal syndrome in children: two cases and literature review

BMC Nephrology, 2019
Background Hemorrhagic fever with renal syndrome (HFRS) is an acute disease caused by hantavirus infection and is clinically characterized by fever, various hemorrhagic manifestations and transient renal and hepatic dysfunctions.
Li Zhang, Qing-shan Ma, Yan Zhang, Bai-chao Sun, Leng-yue Zhao   +4 more
doaj   +1 more source

IKAROS Associated Immunodeficiency and Thrombotic Thrombocytopenic Purpura

Pediatric Blood &Cancer, Volume 73, Issue 2, February 2026.
ABSTRACT Pathogenic variants in IKZF1 (IKAROS) are linked to immunodeficiency, malignancy, and immune dysregulation. We describe a family with a rare IKZF1 variant presenting with humoral immunodeficiency and thrombotic thrombocytopenic purpura (TTP). A non‐consanguineous family was clinically monitored; clinical, immunological, and genetic data (exome
Ilia Spivak, Daniella Magen, Karin Weiss, Tamar Paperna, Suhair Hanna, Amos Etzioni, Adi Miller‐Barmak, Yonatan Butbul Aviel   +7 more
wiley   +1 more source

Pulmonary involvement in hemorrhagic fever with renal syndrome

International Journal of Infectious Diseases
Introduction: Hemorrhagic fever with renal syndrome (HFRS) has recently begun to change its clinical features. Involving the lungs in the inflammatory process started to be recorded not only in rare cases of severe disease but also in patients with a ...
Professor Vera Pavelkina, PhD Rimma Almiasheva, Prof Natalia Pshenichnaya   +2 more
doaj   +1 more source

Chronic Renal Dysfunction in Hemorrhagic Fever with Renal Syndrome Patients

Renal Failure, 1993
During the last 9 years, 32 cases of hemorrhagic fever with renal syndrome (HFRS) have been diagnosed in our institution. Seven patients died. Twenty-three patients were discharged healthy while in another 2 some degree of renal dysfunction, which remained stable 12-15 months later, was evident.
Elisaf, M. S., Korakis, H., Siamopoulos, K. C.   +2 more
openaire   +3 more sources

Oncologic Emergencies: Immune-Based Cancer Therapies and Complications [PDF]

, 2020
Cancer therapies have undergone several recent advancements. Current cancer treatments include immune-based therapies comprised of checkpoint inhibitors, and adoptive immunotherapy; each treatment has the potential for complications that differ from ...
Brém, Elizabeth, Koyfman, Alex, Long, Brit Jeffrey   +2 more
core  

Murine cytomegalovirus genomic material in marrow cells; relation to altered leukocyte counts during sublethal infection of mice [PDF]

, 1987
To investigate infection of hematopoietic cells by murine cytomegalovirus (MCMV), we used in situ hybridization to detect MCMV genomic material in marrow cells during sublethal infection of three-week-old mice.
Bale, J. F., Giller, R., Koszinowski, Ulrich H., O'Neil, M. E., Perlman, S.   +4 more
core   +1 more source

Acute collapse in a dog with multiple autoimmune syndromes and polymyositis complicated by suspected organophosphate/carbamate toxicity

Veterinary Record Case Reports, Volume 14, Issue 1, February 2026.
Abstract A 6.5‐year‐old, spayed, female dog presented in acute respiratory distress. On admission, the dog exhibited dyspnoea, bradycardia, cyanosis and gastrointestinal signs, requiring immediate intubation and mechanical ventilation. Diagnostic evaluation revealed reduced butyrylcholinesterase activity, non‐cardiogenic pulmonary oedema, elevated ...
Sarah Hefer, Efrat Kelmer, Michal Mazaki Tovi, Dana Peery, Kobi Aharoni, Nir Edry, Sigal Klainbart   +6 more
wiley   +1 more source

Hemorrhagic fever with renal syndrome complicated by orchitis

Virologica Sinica, 2011
Hemorrhagic fever with renal syndrome (HFRS) is a disease caused by viruses of the family Bunyaviridae, genus Hantavirus. HFRS from Dobrava virus (DOBV) is a seldom reported disease in Albania. Clinically HFRS is manifested as mild, moderate, or severe.
Edmond, Puca, Arben, Pilaca, Pellumb, Pipero, Silva, Bino, Majlinda, Kote, Elton, Rogozi, Entela, Puca, Dhimiter, Kraja   +7 more
openaire   +3 more sources