Results 21 to 30 of about 552,637 (194)

The Effect of Blood Loss in the Presence and Absence of Severe Soft Tissue Injury on Hemodynamic and Metabolic Parameters; an Experimental study

open access: yesArchives of Academic Emergency Medicine, 2018
Introduction: The effect of severe soft tissue injury on the severity of hemorrhagic shock is still unknown. Therefore, the present study was aimed to determine hemodynamic and metabolic changes in traumatic/hemorrhagic shock in an animal model. ...
Ali Mohammad Moradi   +8 more
doaj   +1 more source

Causes of metabolic acidosis in canine hemorrhagic shock : role of unmeasured ions [PDF]

open access: yes, 2007
Introduction: Metabolic acidosis during hemorrhagic shock is common and conventionally considered to be due to hyperlactatemia. There is increasing awareness, however, that other nonlactate, unmeasured anions contribute to this type of acidosis ...
Faithfull, N. Simon   +25 more
core   +1 more source

The effect of p38 mitogen-activated protein kinase activation on inflammatory liver damage following hemorrhagic shock in rats. [PDF]

open access: yesPLoS ONE, 2012
Hemorrhagic shock is a frequent cause of liver failure and often leads to a fatal outcome. Several studies have revealed that p38 MAPK is a key mediator in hemorrhagic damage of the primary organs through the activation of proinflammatory cytokines such ...
Hiroaki Sato   +2 more
doaj   +1 more source

Extracorporeal immune therapy with immobilized agonistic anti-Fas antibodies leads to transient reduction of circulating neutrophil numbers and limits tissue damage after hemorrhagic shock/resuscitation in a porcine model [PDF]

open access: yes, 2010
Background: Hemorrhagic shock/resuscitation is associated with aberrant neutrophil activation and organ failure. This experimental porcine study was done to evaluate the effects of Fas-directed extracorporeal immune therapy with a leukocyte inhibition ...
Sarah Sadek   +41 more
core   +1 more source

Role of activated dynamin-related protein 1-mediated glutathione metabolism in regulation of mitochondrial dysfunction after hemorrhagic shock

open access: yesDi-san junyi daxue xuebao, 2020
Objective To explore the relationship between activated dynamin-related protein 1 (Drp1)-mediated mitochondrial function and energy metabolism after hemorrhagic shock and clarify its potential mechanisms.
DUAN Chenyang   +4 more
doaj   +1 more source

Vasopressors: Do they have any role in hemorrhagic shock?

open access: yesJournal of Anaesthesiology Clinical Pharmacology, 2017
The priority in the management of patients with traumatic hemorrhagic shock is to control the bleeding with simultaneous volume resuscitation to maintain adequate tissue perfusion.
Babita Gupta   +2 more
doaj   +1 more source

Protective effect of pericytes against vascular leakage in rats with hemorrhagic shock

open access: yesDi-san junyi daxue xuebao, 2020
Objective To investigate the protective effect of pericytes (PCs) against vascular leakage in rats with hemorrhagic shock. Methods Sixty-four 12- to 24-week-old SD rats weighing 200~220 g were randomized equally into sham-operated group, hemorrhagic ...
HE Shuangshuang   +5 more
doaj   +1 more source

Hydrogen sulfide in posthemorrhagic shock mesenteric lymph drainage alleviates kidney injury in rats [PDF]

open access: yesBrazilian Journal of Medical and Biological Research, 2015
Posthemorrhagic shock mesenteric lymph (PHSML) is a key factor in multiple organ injury following hemorrhagic shock. We investigated the role of hydrogen sulfide (H2S) in PHSML drainage in alleviating acute kidney injury (AKI) by administering D,L ...
B. Han   +4 more
doaj   +3 more sources

The Role of Cytokines in Activation of Coagulation and Fibrinolysis in Dengue Shock Syndrome [PDF]

open access: yes, 2002
In a prospective clinical study of 50 patients with Dengue Shock Syndrome (DSS), we investigated the association of tumor necrosis factor- (TNF-), interleukin-1 (IL-1), IL-1 receptor antagonist (IL-1Ra), and IL-6 with activation markers of coagulation
Dolmans, Wil M.V.   +31 more
core   +2 more sources

Oxygen Regime and Exchange of Ammonia in the Sensomotor Cortex of Cats During Blood Loss and Hyperbaric Oxygenation

open access: yesОбщая реаниматология, 2020
Purpose. To study the effect of hyperbaric oxygenation (HBO) on the oxygen regime and ammonia metabolism in the neurons of cat cortex in hemorrhagic shock.Material and methods. Experiments were performed on 164 cats (males).
V. N. Yakovlev, P. N. Savilov
doaj   +1 more source

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