Hemorrhagic stroke - Open Access .click

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Hemorrhagic transformation in patients with ischemic stroke and atrial fibrillation: to anticoagulate or not, that is the question

The management of anticoagulation in patients with ischemic stroke and atrial fibrillation (AF) poses a critical dilemma due to the inherent risk of hemorrhagic transformation.
Vasconcelos, Tiago +4 more
core +1 more source

Mechanical Thrombectomy Versus Medical Management for Large Ischemic Core Stroke Identified before Inter‐Hospital Transfer: A Post Hoc Analysis of the LASTE Trial

Annals of Neurology, EarlyView.
Objective This study assessed the efficacy of thrombectomy in acute ischemic stroke because of large‐vessel occlusion (AIS‐LVO) initially admitted to primary stroke centers (PSC) and subsequently transferred to a comprehensive stroke center (CSC), with a large ischemic core identified before transfer.
Pierre Seners +258 more
wiley +1 more source

A critical reappraisal of the carotid sinus and carotid bulb: Distinguishing neurohistological function from vascular geometry

The Anatomical Record, EarlyView.
This review redefines the carotid bulb (CB) as a variable geometric dilation shaped by hemodynamics and the carotid sinus (CS) as a conserved neurohistological baroreceptor field. Distinguishing these entities clarifies a century of anatomical confusion and links geometry, neurohistology, and clinical interpretation within a unified framework ...
Răzvan Costin Tudose, Nicolae Radu, Mugurel Constantin Rusu +2 more
wiley +1 more source

Clinical neuroanatomy teaching at Peking University Health Science Center: Evolution, current practice, and future direction

Anatomical Sciences Education, EarlyView.
Abstract Neuroanatomy has been considered one of the most challenging subjects in medical education, often leading to “neurophobia” and discouraging students from pursuing neurological specialties. At PKUHSC, the curriculum has evolved from a traditional, discipline‐based model to a technology‐enhanced, integrated “Nervous System” module for ...
Xuan Fang +9 more
wiley +1 more source

Stroke Clinician Interviews the Co-Founders of Phagenesis

Stroke Clinician recently had the opportunity to interview Drs. Shaheen Hamdy, Chief Scientific Officer and Conor Mulrooney, Chief Operating Officer of Phagenesis. Drs.
Clinician, Stroke
core +1 more source

Mobile health interventions to improve adherence to oral anticoagulant treatment: A systematic review and critical analysis

British Journal of Clinical Pharmacology, EarlyView.
Aims Non‐adherence to oral anticoagulants (OACs) is associated with significant morbidity and mortality. Mobile health (mHealth) interventions have been used to improve medication adherence across the three phases of initiation, implementation and persistence.
Non Davies, Elin Haf Davies, Dyfrig A. Hughes +2 more
wiley +1 more source

Clinical Phenotypes and Survival of Stroke Patients Admitted to Intensive Care Units in Kinshasa : A Multicenter Cross-Sectional Study

Annals of Medicine and Medical Sciences
Background: Stroke is a leading cause of death and disability worldwide, with disproportionately high mortality in sub-Saharan Africa. Data on the clinical characteristics and outcomes of critically ill stroke patients in intensive care units (ICUs) in ...
Rodrigue Ngwizani +11 more
doaj

Exposure to CYP2C19‐metabolized drugs following acute stroke: A longitudinal cohort study to inform implementation of CYP2C19 genotype testing

British Journal of Clinical Pharmacology, EarlyView.
Aims Cytochrome P450 2C19 (CYP2C19) genotype testing is recommended to guide antiplatelet selection after ischaemic stroke and transient ischaemic attack. CYP2C19 also metabolizes several commonly prescribed non‐antiplatelet drugs. We aimed to quantify exposure to CYP2C19‐metabolized drugs in stroke patients at hospital discharge and during ...
Cleodie C. Swire +3 more
wiley +1 more source

Comparing outcomes using low‐dose apixaban and anti‐Xa monitoring and vitamin K antagonists in patients with renal replacement therapy

British Journal of Clinical Pharmacology, EarlyView.
Background Guidelines recommend oral anticoagulation for stroke prevention in atrial fibrillation and secondary prevention of venous thromboembolism. Outside the United States, apixaban is unlicensed for use in patients with end‐stage renal disease (ESRD) receiving renal replacement therapy (RRT).
John K. Bartoli‐Abdou +10 more
wiley +1 more source

Targeting neutrophil extracellular traps in metabolic and immune niche: Nanomaterials for diabetes tissue regeneration

BMEMat, EarlyView.
The effects of NETs on regeneration of various diabetic tissues, and strategies targeting NETs for diabetes tissue regeneration. In the diabetic environment, NETs undergo complex metabolic and immune reprogramming, leading to dynamic changes in antibacterial and proinflammatory functions, and affecting regeneration of multiple systemic tissues.
Xinyi Jiang +6 more
wiley +1 more source

stroke
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cerebral hemorrhage
ischemic stroke
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intracranial hemorrhages
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