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Background Peptic ulcer bleeding remains a typical medical emergency with significant morbidity and mortality. Peptic ulcer rebleeding often occurs within three days after emergent endoscopic hemostasis.
Yongkang Lai+9 more
doaj +2 more sources
New Endoscopic Technologies and Procedural Advances for Endoscopic Hemostasis [PDF]
Endoscopic interventions are first-line therapy for upper and lower gastrointestinal bleeding. Injection therapy in combination with a second endoscopic modality has reduced re-bleeding, need for surgery and mortality in non-variceal bleeding. For variceal bleeding endoscopic banding or cyanoacrylate injection techniques are recommended interventions ...
Kenneth F. Binmoeller, Frank Weilert
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Devices for endoscopic hemostasis of nonvariceal GI bleeding (with videos) [PDF]
Endoscopic intervention is often the first line of therapy for GI nonvariceal bleeding. Although some of the devices and techniques used for this purpose have been well studied, others are relatively new, with few available outcomes data.In this document, we review devices and techniques for endoscopic treatment of nonvariceal GI bleeding, the evidence
Mansour A. Parsi+13 more
openaire +5 more sources
Evolving techniques for gastrointestinal endoscopic hemostasis treatment [PDF]
With mortality due to gastrointestinal (GI) bleeding remaining stable, the focus on endoscopic hemostasis has been on improving other outcomes such as rebleeding rate, need for transfusions, and need for angiographic embolization or surgery. Over the past few years, a number of devices have emerged to help endoscopically assess and treat bleeding GI ...
Ghassemi, Kevin A, Jensen, Dennis M
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Background Upper gastrointestinal bleeding (UGIB) due to peptic ulcer disease is one of the leading causes of death in patients with non-variceal bleeding, resulting in up to 10% mortality rate, and the patient group at high risk of rebleeding (Forrest ...
Aleksejs Kaminskis+8 more
doaj +2 more sources
Endoscopic hemostasis state of the art - Nonvariceal bleeding
New endoscopic techniques for hemostasis in nonvariceal bleeding were introduced and known methods further improved. Hemospray and Endoclot are two new compounds for topical treatment of bleeding. Initial studies in this area have shown a good hemostatic effect, especially in active large scale oozing bleeding, e.g., tumor bleedings.
Goelder, Stefan Karl+2 more
openaire +4 more sources
Hemostasis in Endoscopic Endonasal Skull Base Surgery [PDF]
William Halsted established the basic principles of modern surgical technique highlighting the importance of meticulous hemostasis and careful tissue handling. These concepts hold true today and are even more critical for endoscopic visualization, making hemostasis one of the most relevant cornerstones for the safe practice of endoscopic endonasal ...
Juan C. Fernandez-Miranda+5 more
openaire +4 more sources
Background and Objectives: A novel synthetic self-assembling peptide, PuraStat, has been introduced as a hemostatic agent. This case series aimed to evaluate the clinical efficacy of PuraStat for gastrointestinal bleeding during emergency endoscopy ...
T. Murakami+7 more
semanticscholar +1 more source
Self-assembling peptides (PuraStat; 3-D Matrix, Tokyo, Japan) are novel synthetic self-assembling peptides that are licensed for use as a hemostat [1]. The matrix forms an extracellular scaffold that is activated by the change in pH on contact with blood
Daisuke Yamaguchi+6 more
semanticscholar +1 more source
Introduction: Recently, a novel self-assembling peptide hemostatic gel has become available in Japan. However, the safety and efficacy of this novel self-assembling peptide hemostatic gel remain unclear for bleeding after EST.
Yuki Uba+11 more
semanticscholar +1 more source