Results 251 to 260 of about 32,799 (334)

New Technologies Empower Hemophilic Arthropathy Treatment: Focusing on Regenerative Medicine, Molecular Targeting, and Gene Therapy

open access: yesMedicine Bulletin, EarlyView.
ABSTRACT Hemophilic arthropathy (HA), a major complication of hemophilia, is a chronic osteoarthropathy driven by repeated joint bleeding. Although traditional therapies such as coagulation factor replacement, physical rehabilitation, and surgery can manage symptoms, they cannot fundamentally repair established joint damage or break the pathological ...
Lin Sun   +8 more
wiley   +1 more source

The efficacy of a hemostatic agent in anticoagulant drug-induced rat bleeding model

open access: bronze, 2014
Ertan Sönmez   +7 more
openalex   +1 more source

Menstrual suppression to decrease intrauterine device expulsion in adolescents with inherited bleeding disorders

open access: yes
International Journal of Gynecology &Obstetrics, Volume 169, Issue 1, Page 421-423, April 2025.
Peter H. Cygan   +3 more
wiley   +1 more source

Hemophilia A: An Ideal Disease for Prenatal Therapy

open access: yesPrenatal Diagnosis, EarlyView.
ABSTRACT Hemophilia A (HA) is the most common inherited coagulation defect. Current state‐of‐the‐art treatment consists of frequent administration of prophylactic infusions of coagulation factor VIII (FVIII) protein or bispecific antibodies that replace the cofactor function of FVIIIa to maintain hemostasis. However, these treatments are far from ideal,
Christopher D. Porada   +2 more
wiley   +1 more source

Hydrogel Microneedle Array‐Based Transdermal Dressing System for Multiplexed Assessment and Intelligent Therapy of Chronic Wounds

open access: yesSmall, EarlyView.
This work develops a theranostic wound microneedle dressing integrates a therapeutic MXene‐infused hydrogel with a high‐conductive sensor array enabled by a novel laser‐scribing technique. The platform actively promotes wound healing and provides antibacterial action while continuously monitoring seven key biomarkers.
Md Sharifuzzaman   +6 more
wiley   +1 more source

Comparative Efficacy of Two Hemostatic Agents in Post-Extraction Bleeding Control Following Mandibular Third Molar Surgery: A Randomized Clinical Trial [PDF]

open access: gold
Giovanna Pesce   +7 more
openalex   +1 more source

An Integrated Method to Evaluate the Treatment Efficacy and Immunogenicity of B‐Cell Acute Lymphoblastic Leukemia Therapeutic Enzyme Formulations

open access: yesSmall Methods, EarlyView.
This work presents an integrated set of methods to evaluate the efficacy of asparaginase formulations against B‐cell Acute Lymphoblastic Leukemia (ALL) in mice, including the establishment of an ALL murine model, an amino acid depletion study using high‐performance liquid chromatography (HPLC), and comprehensive assessment of antibody production ...
Julien Santelli   +6 more
wiley   +1 more source

Emerging Triboelectric Nanogenerators for In‐Body Implantation

open access: yesSmall Methods, EarlyView.
This review explores functional implantable triboelectric nanogenerators in biomedical applications, discussing their mechanisms, electricity generation, and design approaches. To solve postimplantation challenges, four types of triboelectric nanogenerators (TENGs) are introduced: stretchable, bioadhesive, on‐demand biodegradable, and multiresponsive ...
Xiao Xiao   +4 more
wiley   +1 more source

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