Results 271 to 280 of about 32,799 (334)

A Breakthrough in Hemostatic Agents For Dentistry: Will They Be a Game Changer?

Nanda Kishore Ghoshal
openalex   +2 more sources

Centaurea behen leaf extract mediated green synthesized silver nanoparticles as antibacterial and removing agent of environmental pollutants with blood compatible and hemostatic effects [PDF]

Mohadese Abdoli, Salar Khaledian, Maryamosadat Mavaei, Pouria Hajmomeni, Mahnaz Ghowsi, Farshad Qalekhani, Houshang Nemati, Ali Fattahi, Komail Sadrjavadi   +8 more
openalex   +1 more source

Current gynaecological management of women and girls with bleeding disorders in the United Kingdom: A UKHCDO haemophilia treatment centre survey and evaluation of real‐world clinical practice for the British Journal of Haematology

British Journal of Haematology, EarlyView.
Summary Girls and women with bleeding disorders (GWBD) comprise more than half of all registered patients with bleeding disorders in the UK National Haemophilia Database. The gynaecological care of GWBD, until recently, has not been prioritised despite high health burdens, where four of every five patients experience heavy menstrual bleeding (HMB).
Laura Knox, Imogen Swart‐Rimmer, Naim Rahimi, Callum Harris, Lugain Abdalla, Gary Benson, Clare Brown, Helen Campbell, Ana Carvalhosa, Justin T. Clarke, Sarah Garside, Claire Lentaigne, Jayna Mistry, Priyanka Raheja, Cora Warren, Rezan Abdul‐Kadir, Gill Lowe, Nicola Curry   +17 more
wiley   +1 more source

Opportunities for improving platelet transfusion practice: A large retrospective audit across 22 hospitals

British Journal of Haematology, EarlyView.
Summary Despite evidence‐based guidelines to inform platelet transfusion practice, unnecessary platelet transfusion persists. We performed a multicentre retrospective analysis of adults admitted to general medicine, subspecialty medicine and critical care from 1 January 2017 to 30 June 2022.
Sarah Ryan, Yang Liu, Sheharyar Raza, Anne Loeffler, Nicole Relke, Nadia Gabarin, Malcolm Risk, Phuong Uyen Nguyen, Na Li, Amol Verma, Fahad Razak, Keyvan Karkouti, Janique Dyba, Donald Arnold, Jeannie Callum   +14 more
wiley   +1 more source

Targeting MCL‐1 and MAPK overcomes venetoclax resistance in FLT3‐ITD‐positive AML cells harbouring activating PTPN11 (SHP‐2) mutations

British Journal of Haematology, EarlyView.
Summary Venetoclax (VEN)‐based therapies have improved the treatment of acute myeloid leukaemia (AML); however, the emergence of resistance remains a major limitation. Mutations in protein tyrosine phosphatase (PTP) non‐receptor type 11 (PTPN11) and FMS like tyrosine kinase 3 with internal tandem duplication (FLT3‐ITD) are common in resistant patients ...
Maximilian Fleischmann, Ole Hansen, Diana Voigtländer, Julia Bechwar, Lenny‐Joseph Schwietzer, Sanja Bahr, Ulf Schnetzke, Mike Fischer, Florian H. Heidel, Tina M. Schnöder, Jörg P. Müller, Andreas Hochhaus, Sebastian Scholl   +12 more
wiley   +1 more source

Reflections on the Potential of Applying Artificial Intelligence (AI) and Machine Learning (ML) for Screening Topical Hemostatic Agents Based on Inorganic Solids for Hemorrhage Control

Guilherme de Paula Guarnieri, José Geraldo Nery   +1 more
openalex   +2 more sources

Open Questions in Surgery for Hepatoblastoma: A Joined SIOPEL‐IPSO Survey

European Journal of Haematology, EarlyView.
ABSTRACT Introduction Surgery is pivotal in the management of hepatoblastoma (HB) although approaches and techniques may vary. The Liver Group of the International Society of Pediatric Oncology (SIOPEL) and the International Pediatric Surgical Oncology (IPSO) group collaborated to develop an online survey to investigate specific technical aspects and ...
Chiara Grimaldi, Francesca Gigola, Reto M. Baertschiger, Marco Del Riccio, Hanna Garnier, Gloria Gonzalez, York Tien Lee, Amos Loh, Luca Pio, Sophie Branchereau   +9 more
wiley   +1 more source

Safer Access With Fewer Transfusions: Revisiting Platelet Thresholds in Pediatric Central Venous Catheterization

European Journal of Haematology, EarlyView.
ABSTRACT Background Central venous catheters (CVCs) are essential in pediatric hematology‐oncology, for the administration of chemotherapy and supportive therapy. Thrombocytopenia increases the risk of bleeding and current guidelines recommend prophylactic platelet transfusions below 40–50 × 109/L, though evidence is limited and transfusions entail ...
Alessandro Raffaele, Carlo Maria Ferlini, Marta Gazzaneo, Piero Giovanni Romano, Bilge Rol, Francesco Delle Cave, Stella Boghen, Tommaso Mina, Marco Zecca   +8 more
wiley   +1 more source

In combat casualties with active external bleeding, do the hemostatic devices and agents used by Spanish military provide adequate hemodynamic stabilization for evacuation to a safe zone, following the Tactical Combat Casualty Care protocol?

Tripdatabase
openalex   +1 more source

TGFβ enhances platelet–breast‐cancer‐cell interaction and promotes platelet aggregation

The FEBS Journal, EarlyView.
TGFβ stimulation promotes EMT in MCF7 cells, increasing their ability to bind, activate, and aggregate PLT. This effect involves the upregulation of adhesion molecules Integrin‐αv and Galectin‐3. Inhibiting Integrin‐αv or Galectin‐3, through Cilengitide and GB1103, reduces PLT adhesion to MCF7 and PLT aggregation, suggesting a mechanism linking TGFβ ...
Margherita Genitoni, Lucia Merolle, Agnese Razzoli, Eleonora Maurizi, Gaia Gavioli, Roberto Baricchi, Chiara Marraccini, Davide Schiroli   +7 more
wiley   +1 more source