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Development of Hemostatic Agents [PDF]
, 2005 Abstract : To translate investigational hemostatic agents developed in the rat model to swine models of lethal groin injury and liver laceration. This objective evaluated the efficacy of patch and granule formulations of capsaicin (CP-305) in normal and coagulopathic swine models.
Bob M, Moore
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Hemostatic Agents and Their Safety
Journal of Cardiothoracic and Vascular Anesthesia, 1999The pharmacologic management of hemostasis in patients undergoing cardiopulmonary bypass may be accompanied by adverse responses. Evaluating the safety profile of hemostatic agents (eg, lysine analogs, aprotinin, protamine, or even donor blood) should be done objectively.
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American Journal of Health-System Pharmacy, 2006
The pharmacology, clinical efficacy, adverse effects and toxicities, drug interactions, dosage and administration, and safety issues related to the use of absorbable hemostatic agents are reviewed.Absorbable hemostatic agents exert their pharmacologic effects at various points within the coagulation cascade.
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The pharmacology, clinical efficacy, adverse effects and toxicities, drug interactions, dosage and administration, and safety issues related to the use of absorbable hemostatic agents are reviewed.Absorbable hemostatic agents exert their pharmacologic effects at various points within the coagulation cascade.
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Chitosan-Coated Diatom Silica as Hemostatic Agent for Hemorrhage Control.
ACS Applied Materials and Interfaces, 2016Uncontrolled hemorrhage leads to high death risk both in military and civilian trauma. Current hemostatic agents still have various limitations and side effects. In this study, natural diatom silica obtained from diatomite and diatom culture was purified
Chao Feng +8 more
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Synthesis and properties of poly(DEX-GMA/AAc) microgel particle as a hemostatic agent.
Journal of materials chemistry. B, 2017Immediate hemorrhage control without secondary injury is pivotal for saving lives. In this study, polymerized glycidyl methacrylate derivative dextran/acrylic acid (poly(DEX-GMA/AAc)) microgel particles were prepared via emulsion polymerization method as
Changjiao Yan +3 more
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SULFAPYRIDINE AS A HEMOSTATIC AGENT
Archives of Dermatology, 1945In 1942 Cunningham 1 reported on the use of sulfapyridine as a hemostatic agent. He found that after sulfamethylthiazole powder had been instilled into the operative wound after radical external frontal sinusotomy for osteomyelitis of the frontal bone the usual considerable postoperative oozing was absent.
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Desmopressin: A Nontransfusional Hemostatic Agent
Annual Review of Medicine, 1990Desmopressin (1-deamino-8-D-arginine vasopressin, DDAVP) is a synthetic analogue of the antidiuretic hormone L-arginine vasopressin. Because it can raise circulating levels of Factor VIII and of von Willebrand's factor, DDAVP is used for nontransfusional treatment of mild and moderate hemophilia and von Willebrand's disease.
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Local Hemostatic Agents (and Techniques)
Scandinavian Journal of Haematology, 1984Historically, control of bleeding in the mouth has been a challenge to oral surgeons who treat patients with acquired, idiopathic and congenital bleeding disorders. This discussion focuses on the local measures currently utilized to control bleeding in the oral cavity.
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2014
Hemostasis in the operating theatre has always been an issue of fundamental importance in any surgical procedure. The amount of blood loss may greatly vary between different surgical procedures and depends on both surgical and non-surgical factors.
Di Benedetto F., Tarantino G.
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Hemostasis in the operating theatre has always been an issue of fundamental importance in any surgical procedure. The amount of blood loss may greatly vary between different surgical procedures and depends on both surgical and non-surgical factors.
Di Benedetto F., Tarantino G.
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Hemostatic Agents in Surgical Oncology [PDF]
, 2010 A wide variety of hemostatic agents and sealants have been developed as surgical tools, of which the uses now range beyond their namesake. According to FDA regulations, an hemostatic agent is defined as a device intended to produce hemostasis by accelerating the clotting process of blood.
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