Results 81 to 90 of about 31,538 (351)

Topical hemostatic powders in the management of gastrointestinal bleeding

International Journal of Gastrointestinal Intervention
Hemostatic powders were developed to overcome limitations associated with conventional endoscopic techniques, and their use in gastrointestinal bleeding is increasing exponentially.
Jongbeom Shin, Boram Cha, Ji Taek Hong, Jin Hee Maeng, Kye Sook Kwon   +4 more
doaj   +1 more source

Modern concepts of the platelet in health and disease [PDF]

, 1962
Thesis (M.D.)--Boston ...
Estes, J. Worth
core  

Selective Inhibition of Integrin β3 Topology Provides a Safer Antithrombotic Strategy

Advanced Science, EarlyView.
Current integrin αIIbβ3 inhibitors effectively reduce thrombosis but also increase bleeding risk. During thrombosis, high shear blood flow can directly activate the integrin αIIbβ3 via a distinct topological change in the β3 transmembrane domain, independent of hemostatic platelet signaling.
Joonha Lee, Chul‐Gyun Lim, Pothiappan Vairaprakash, Jong‐Min Kim, Jiyoon Kim, Ji‐Young Park, Klaus M. Hahn, Hyunbo Shim, Hae Woong Choi, Tobias S. Ulmer, Soon Jun Hong, Chungho Kim   +11 more
wiley   +1 more source

Effect of Different Cleansing Protocols on Bond Strength of Composite Resin to Dentin Contaminated with Hemostatic Agent: An In Vitro Study

Frontiers in Dentistry, 2020
Objectives: Inadequate removal of the hemostatic agent can adversely affect the bond strength of restorations to the tooth structure. This study aimed to assess the effect of different cleansing protocols on the shear bond strength (SBS) of an etch-and ...
Keivan Saati, Seyedeh Farnaz Tabatabaei, Delaram Etemadian, Morad Sadaghiani   +3 more
doaj   +1 more source

Benefit of Apabetalone on Plasma Proteins in Renal Disease. [PDF]

, 2018
Introduction:Apabetalone, a small molecule inhibitor, targets epigenetic readers termed BET proteins that contribute to gene dysregulation in human disorders. Apabetalone has in vitro and in vivo anti-inflammatory and antiatherosclerotic properties.
Gilham, Dean, Halliday, Christopher, Jahagirdar, Ravi, Johansson, Jan O, Kalantar-Zadeh, Kamyar, Kulikowski, Ewelina, Robson, Richard, Stotz, Stephanie C, Sweeney, Michael, Tsujikawa, Laura M, Wasiak, Sylwia, Wong, Norman C   +11 more
core   +2 more sources

Laparoscopic Delivery of a MnO2‐P‐ICG Patch for Photodynamic Therapy and NK Cell‐Driven Immunotherapy in Hepatocellular Carcinoma

Advanced Science, EarlyView.
This study proposes a flexible MnO2‐P‐ICG nanofiber patch for laparoscopic treatment of liver tumors. The patch alleviates tumor hypoxia and induces photodynamic therapy (PDT) triggered immunogenic cell death, thereby activating the cGAS‐STING pathway and, in synergy with pachymaran, promoting NK cell–mediated innate immunity. This synergistic strategy
Jie Lin, Haoqi Pan, Ke Wu, Junjie Nan, Jinyao Dai, Yushun Chang, Hao Shen, Qingxuan Ye, Haowen Lu, Yuxuan Shen, Boqiang Liu, Ming Wu, Jicheng Yu, Xiujun Cai, Dong Cen   +14 more
wiley   +1 more source

Polyelectrolyte Complex-Based Chitosan/Carboxymethylcellulose Powdered Microgels Loaded with Eco-Friendly Silver Nanoparticles as Innovative Biomaterials for Hemostasis Treatments

Polysaccharides
Uncontrolled hemorrhage is a major global health issue, causing high mortality rates in both civilian and military settings. The risk of infection in bleeding wounds highlights the need for effective hemostatic materials.
Ariel Gonzalez, Micaela Ferrante, Liesel Gende, Vera A. Alvarez, Jimena S. Gonzalez   +4 more
doaj   +1 more source

Development of haemostatic decontaminants for treatment of wounds contaminated with chemical warfare agents. 3: Evaluation of in vitro topical decontamination efficacy using damaged skin [PDF]

, 2017
This document is the Accepted Manuscript version of the following article: Lydon, H. L., Hall, C. A., Dalton, C. H., Chipman, J. K., Graham, J. S., and Chilcott, R.
Acheson, Alam, Alam, Arnaud, Chilcott, Chilcott, Chilcott, Chilcott, Chilcott, Cox, Creasy, Dalton, Dalton, Davies, Freeman, Griffiths, Grotenhuis, Hall, Hooidonk, Jokanović, Kheirabadi, Kozen, Leonard, Li, Ling, Littlejohn, Mabry, Munro, OECD, Pusateri, Pusateri, Scheuplein, Schlupp, Schreiber, Shanmugam, Spalding, Vallet, Wedmore, Wu, Zhai   +39 more
core   +2 more sources

Lyophilized Synthetic Platelets: In Vitro Characterization and in Vivo Evaluation in Mouse Thrombocytopenia Model

Advanced Science, EarlyView.
ABSTRACT Platelet transfusions to treat bleeding complications use donor‐derived platelets stored at room‐temperature, that have a shelf‐life of only 5–7 days due to bacterial contamination risks. Cold‐stored and freeze‐dried platelets are being investigated for extending shelf‐life, but these still have the inherent challenge of donor‐dependency.
Ujjal Didar Singh Sekhon, Dante Disharoon, Shrijal S. Desai, Baylee Traylor, Emily Gahagan, Emma Quill, Kristin Aldridge, Norman F. Luc, Sonali Rohiwal, Shruti Raghunathan, Rebecca Ahn, Sana Syed, Alexander Dornback, Bipin Chakravarthy Paruchuri, Andrew Ditto, Susan M. Shea, Philip C. Spinella, Matthew D. Neal, Michael A. Bruckman, Christa L. Pawlowski, Anirban Sen Gupta   +20 more
wiley   +1 more source

Hemostatic Agents for the Management of Bleeding Risk Associated with Oral Anticoagulant Therapy Following Tooth Extraction: A Systematic Review [PDF]

, 2022
Marco Nisi, Elisabetta Carli, Stefano Gennai, Francesco Gulia, Rossana Izzetti   +4 more
openalex   +1 more source