Results 11 to 20 of about 1,326 (138)

Soluble E-Cadherin as a New Prognostic Biomarker Able to Predict Survival in Newly Diagnosed Diffuse Large B-Cell Lymphoma [PDF]

Biomolecules
Background: Diffuse large B-cell lymphoma (DLBCL) is the most common subtype of non-Hodgkin lymphoma, constituting an important public health problem. Although curable, it presents a widely variable prognosis.
Paola Carolina Rabesquini Marcelino da Silva, Igor Cerejo Tavares da Silva de Almeida, Joaquim Gasparini dos Santos, Leonardo Jun Otuyama, Cadiele Oliana Reichert, Hebert Fabrício Culler, Nélio Cézar de Aquino, Lilian de Souza França, Sheila Aparecida Coelho da Siqueira, Renata de Oliveira Costa, Vanderson Rocha, Sérgio Paulo Bydlowski, Débora Levy, Juliana Pereira, Luís Alberto de Pádua Covas Lage   +14 more
doaj   +2 more sources

Overall survival in multiple myeloma in Brazil: A cohort of 16 years [PDF]

Hematology, Transfusion and Cell Therapy
Multiple myeloma constitutes approximately 1 % of all malignancies, with a higher incidence observed in over 65-year-old individuals. New technologies have shown promising results with an increased overall survival. The objective of this cohort study was
Deborah Marta do Santos Oliveira, Isabela Cristina Menezes de Freitas, Wallace Mateus Prata, Isabella Zuppo Laper, Pâmela Santos Azevedo, Adriano de Paula Sabino, Marisa Yurico Itonaga, Carmino Antonio de Souza, Mariângela Leal Cherchiglia, Juliana Alvares Teodoro, Francisco de Assis Acurcio, Augusto Afonso Guerra Junior   +11 more
doaj   +2 more sources

A genetic risk score based on BCL11A and HBS1L-MYB variants predicts clinical severity in Brazilian sickle cell anaemia patients. [PDF]

Br J Haematol
Summary Individuals with sickle cell anaemia (SCA) exhibit significant clinical heterogeneity influenced by several factors, especially fetal haemoglobin (HbF) levels. Variations in adult HbF levels are partly explained by the co‐inheritance of genetic variants that regulate globin expression.
Arcanjo GS, Silva AP, Diniz MV, Domingos IF, Pereira-Martins DA, Araújo AB, França TSS, Anjos AC, Araujo AS, Belini-Junior E, Saad STO, Costa FF, Lucena-Araujo AR, Bezerra MAC.   +13 more
europepmc   +2 more sources

Should the current diagnostic criteria for CLL be reconsidered? A reply to Johnstone et al. "De-diagnosing chronic lymphocytic leukaemia: An ethical and scientific case for changing diagnostic criteria". [PDF]

Hemasphere
HemaSphere, Volume 10, Issue 2, February 2026.
Matos DM.
europepmc   +2 more sources

Psychological Distress, Resilience, and Immunoinflammatory Signatures in Healthcare Workers During COVID-19. [PDF]

Stress Health
ABSTRACT The COVID‐19 pandemic has profoundly affected healthcare workers, increasing vulnerability to neuropsychiatric disorders, such as anxiety and depression. Psychological distress may be shaped by resilience, coping behaviours, and immune dysregulation.
Fiorenza NG, Silva BRDS, Lós DB, Oliveira NH, Delerino AL, Assis DF, Motta PC, Cortez PC, Silva MFS, Fonseca MHG, Marques JAL, Miyajima VP, Miyajima F, Macedo DS.   +13 more
europepmc   +2 more sources

Frequência de casos de anemia falciforme, transfusão e tratamento – Experiência de um centro de hemoterapia em uma região do nordeste brasileiro / Frequency of sickle cell anemia cases, transfusion and treatment - Experience of a hemotherapy center in a region of northeastern Brazil [PDF]

Brazilian Journal of Health Review, 2021
Objetivou-se analisar o perfil epidemiológico de pacientes portadores de anemia falciforme atendidos no Hemocentro em uma região do nordeste brasileiro. O estudo foi realizado por meio de uma abordagem quantitativa, através da análise de dados de 263 pacientes com anemia falciforme, obtidos a partir de prontuários e fichas de atendimento disponível em ...
Teles, Weber de Santana, de Jesus, Paulo Alexandre Correia, Silva, Layne Cristiane Maria Nascimento, da Silva, Max Cruz, Torres, Ruth Cristini, Azevedo, Marcel Vinícius Cunha, Barros, Ângela Maria Melo Sá, Santos Júnior, Paulo Celso Curvelo, Morais, André Luiz de Jesus, de Andrade, Ana Fátima Souza Melo, Debbo, Alejandra, Silva, Maria Hozana Santos   +11 more
openaire   +2 more sources

Inflammatory cytokine profile in patients with sickle cell anaemia and leg ulcers. [PDF]

Br J Haematol
British Journal of Haematology, Volume 208, Issue 1, Page 373-377, January 2026.
Diniz MV, Silva AP, Arcanjo GS, Batista THC, Rodrigues JVS, Rêgo MJBM, Leão HI, Silva RC, Souto FO, Melo CML, Barros BRS, Anjos ACM, Araújo AS, Domingos IF, Saad STO, Costa FF, Lucena-Araujo AR, Bezerra MAC.   +17 more
europepmc   +2 more sources

Angioimmunoblastic T-cell lymphoma and correlated neoplasms with T-cell follicular helper phenotype: from molecular mechanisms to therapeutic advances

Frontiers in Oncology, 2023
Angioimmunoblastic T-cell lymphoma (AITL) is the second most frequent subtype of mature T-cell lymphoma (MTCL) in the Western world. It derives from the monoclonal proliferation of T-follicular helper (TFH) cells and is characterized by an exacerbated ...
Luís Alberto de Pádua Covas Lage, Luís Alberto de Pádua Covas Lage, Hebert Fabricio Culler, Hebert Fabricio Culler, Cadiele Oliana Reichert, Cadiele Oliana Reichert, Sheila Aparecida Coelho da Siqueira, Juliana Pereira, Juliana Pereira, Juliana Pereira   +9 more
doaj   +1 more source

Tumor Microenvironment Proteomics: Lessons From Multiple Myeloma

Frontiers in Oncology, 2021
Although the “seed and soil” hypothesis was proposed by Stephen Paget at the end of the 19th century, where he postulated that tumor cells (seeds) need a propitious medium (soil) to be able to establish metastases, only recently the tumor ...
Rodrigo Carlini Fernando, Fabrício de Carvalho, Adriana Franco Paes Leme, Gisele Wally Braga Colleoni   +3 more
doaj   +1 more source

Quality control in blood irradiation

Brazilian Journal of Radiation Sciences, 2023
Irradiation is a technique used in hemotherapy to functionally inactivateviable lymphocytes, in cellular blood components, to reduce the risk of Transfusion-associated Graft-versus-Host Disease (AT-GVHD), is rare but letal.
F. Lopes, R.C.G. Rocha, E. Munhoz, F.C. Trigo, V.B.E.R. Feijó, M. Fernandes, T.C. De Paula, L.G. Padilha Filho, G.S. Araujo   +8 more
doaj   +1 more source