Results 51 to 60 of about 1,326 (138)

Immunomodulatory and Anticancer Effects of Fridericia chica Extract-Loaded Nanocapsules in Myeloid Leukemia

Pharmaceutics
Nanocapsules provide selective delivery and increase the bioavailability of bioactive compounds. In this study, we examined the anticancer and immunomodulatory potential of Fridericia chica (crajiru) extract encapsulated in nanocapsules targeting myeloid
Alice de Freitas Gomes, Adriane Dâmares de Souza Jorge Batalha, Carlos Eduardo de Castro Alves, Renata Galvão de Azevedo, Jesus Rafael Rodriguez Amado, Tatiane Pereira de Souza, Hector Henrique Ferreira Koolen, Felipe Moura Araújo da Silva, Francisco Celio Maia Chaves, Serafim Florentino Neto, Antônio Luiz Boechat, Gemilson Soares Pontes   +11 more
doaj   +1 more source

Hepatitis C virus infection in blood donors in Santa Catarina, Brazil, 2010–2020

Transfusion Medicine, Volume 35, Issue 5, Page 486-493, October 2025.
Abstract Introduction Hepatitis C is a silent disease characterised by a persistent inflammatory process in the liver. Since blood is the main route of transmission, the objective of this study was to estimate the positivity rate of hepatitis C virus (HCV) infection in blood donations from the Public Blood Network of the State of Santa Catarina and to ...
Fabiana Schuelter‐Trevisol, Gabriel Tadeu Ossani, Gabriel Oscar Cremona Parma, Daisson José Trevisol   +3 more
wiley   +1 more source

Consensus of the Brazilian association of hematology, hemotherapy and cellular therapy on patient blood management: History and scenario of patient blood management in the world and in Brazil.

Hematology, transfusion and cell therapy
Patient Blood Management (PBM) is a multidimensional approach that seeks to optimize the use of blood and its components in patients. This matter emerged as a response to the need to reduce unnecessary exposure to blood transfusions and their potential risks.
Montano-Pedroso, Juan Carlos, Biagini, Silvana, Macedo, Maria Cristina Martins de Almeida, Ribeiro, Glaciano, Marques Junior, José Franciscos Comenalli, Rizzo, Silvia Renata Cornélio Parolin, Rabello, Guilherme, Langhi Junior, Dante Mario   +7 more
openaire   +3 more sources

Quality control of intraoperative autologous blood salvage in cardiac surgery

Transfusion, Volume 65, Issue 10, Page 1861-1868, October 2025.
Abstract Background The management of intraoperative autologous blood salvage (ABS) quality is essential to ensure safety and outcomes; although publications on this subject are scarce. We evaluated a standardized program of ABS quality control for cardiac and evaluated surgery predictors of mortality in this population. Methods Data from a multicenter
Sergio Domingos Vieira, Fernanda da Cunha Vieira Perini, Leandro Felipe Figueiredo Dalmazzo, Fabiana Akil, Pablo Raphael Gomiero Alves, Erika Abdon Fiquene Oliveira, Marcello Augusto Cesar, Tatiana Covas Pereira, Claudia Monteiro, Mara Cabral Moraes, Katia Beatrice Lima Buratta, Neila Jones Moitinho   +11 more
wiley   +1 more source

DRB1 locus alleles of HLA class II are associated with modulation of the immune response in different serological profiles of HIV-1/Epstein-Barr virus coinfection in the Brazilian Amazon region

Frontiers in Medicine
BackgroundEpstein–Barr virus (EBV) infection involves distinct clinical and serological profiles. We evaluated the frequency of alleles of locus DRB1 of HLA class II in different serological profiles of EBV infection among HIV-1 infected patients ...
Leonn Mendes Soares Pereira, Leonn Mendes Soares Pereira, Eliane dos Santos França, Eliane dos Santos França, Iran Barros Costa, Iran Barros Costa, Igor Tenório Lima, Igor Tenório Lima, Erika Vanessa Oliveira Jorge, Patrícia Jeanne de Souza Mendonça Mattos, Amaury Bentes Cunha Freire, Francisco Lúzio de Paula Ramos, Talita Antonia Furtado Monteiro, Olinda Macedo, Rita Catarina Medeiros Sousa, Rita Catarina Medeiros Sousa, Felipe Bonfim Freitas, Felipe Bonfim Freitas, Igor Brasil Costa, Igor Brasil Costa, Antonio Carlos Rosário Vallinoto, Antonio Carlos Rosário Vallinoto   +21 more
doaj   +1 more source

HTLV-I infection and adult T-cell leukemia in Brazil: an overview

São Paulo Medical Journal
Human T-cell lymphotropic Virus Type I (HTLV-I) is the etiologic factor for adult T-cell leukemia/lymphoma (ATL). HTLV-I infection can also lead to other diseases, such as HTLV -I-associated myelopathy/tropical spastic paraparesis (HAM/TSP), uveitis ...
Maria do Socorro Pombo de Oliveira, Nelson Hamerschlak, Carlos Chiattone, Paula Loureiro   +3 more
doaj   +1 more source

Limitations in occupational performance of individuals with hemophilia in Hemotherapy Regional Center of Ribeirão Preto, Brazil

, 2010
A hemofilia é grave distúrbio hereditário da coagulação sanguínea que resulta em incapacidades que influenciam no desempenho dos acometidos. A tecnologia assistiva (TA) é equipamento ou conjunto de produtos, comprados ou modificados ou feitos sob medida, usados ampliar o desempenho funcional.
Barata-Assad, Danielle Aline, Elui, Valéria Meirelles Carril   +1 more
openaire   +1 more source

Genetic diversity among volunteer donors of bone marrow in southeastern Brazil, according to the HLA system

São Paulo Medical Journal
CONTEXT AND OBJECTIVE: Checking the histocompatibility of the molecules of the human leukocyte antigen (HLA) system is vital for performing bone marrow transplantation with allogeneic material.
Letícia Sarni Roque, Rodolpho Telarolli-Junior, Leonor Castro Monteiro Loffredo   +2 more
doaj   +1 more source

Technical evaluation of serological screening tests for anti-Toxoplasma gondii antibodies to prevent unnecessary transfusion risks Avaliação técnica de testes de triagem sorológica para detecção de anticorpos anti-Toxoplasma gondii como medida preventiva a riscos transfusionais desnecessários

Revista Brasileira de Hematologia e Hemoterapia, 2008
Serological assays to detect anti-Toxoplasma gondii antibodies and specific anamnesis associated with this highly prevalent infection could be necessary in hemotherapy services in order to regulate safer blood supplies thus avoiding unnecessary ...
Rogério S. Vaz, Ana T. B. Guimarães, Larissa D. Bonanato, Vanete Thomaz-Soccol   +3 more
doaj   +1 more source

A Second Wind for Inorganic APIs: Leishmanicidal and Antileukemic Activity of Hydrated Bismuth Oxide Nanoparticles

Pharmaceutics
American cutaneous leishmaniasis is a disease caused by protozoa of the genus Leishmania. Currently, meglumine antimoniate is the first-choice treatment for the disease.
Andriy Grafov, Ana Flávia da Silva Chagas, Alice de Freitas Gomes, Wessal Ouedrhiri, Pierfrancesco Cerruti, Maria Cristina Del Barone, Breno de Souza Mota, Carlos Eduardo de Castro Alves, Anny Maíza Vargas Brasil, Antonia Maria Ramos Franco Pereira, Gemilson Soares Pontes   +10 more
doaj   +1 more source