Results 11 to 20 of about 58,889 (219)
Hepatology, EarlyView., 2022 Increased liver content of DHA‐derived small lipid autacoids (i.e resolvin D1 and maresin 1) associates with enhanced mitochondrial oxidative phosphorylation, fatty acid β‐oxidation and bioenergetic metabolic flux. These features provide hepatic protection from steatotic, pro‐inflammatory and fibrogenic insults.
Cristina López‐Vicario +12 more
wiley +1 more source
The NADPH oxidase NOX4 regulates redox and metabolic homeostasis preventing HCC progression
Hepatology, EarlyView., 2022 Loss of NOX4 in HCC tumor cells induces metabolic reprogramming in a Nrf2/MYC‐dependent manner to promote HCC progression. Abstract Background and Aims The NADPH oxidase NOX4 plays a tumor‐suppressor function in HCC. Silencing NOX4 confers higher proliferative and migratory capacity to HCC cells and increases their in vivo tumorigenic potential in ...
Irene Peñuelas‐Haro +14 more
wiley +1 more source
Integrated Multi-Omic Analysis Identifies Altered Colonic Brush Border Profile as a Key Feature of Microscopic Colitis. [PDF]
United European Gastroenterol JABSTRACT Background Microscopic colitis (MC), comprising lymphocytic colitis (LC) and collagenous colitis (CC), is an inflammatory bowel disease with increasing incidence. MC etiopathogenesis remains unknown; however, altered colonic epithelial integrity may underlie uncontrolled luminal antigen passage, triggering immuno‐inflammatory responses ...
Guagnozzi D +18 more
europepmc +2 more sources
Hepatology, EarlyView., 2022 Natural history of liver disease in a large international cohort of children with Alagille syndrome: Results from the GALA study. Abstract Background and Aims Alagille syndrome (ALGS) is a multisystem disorder, characterized by cholestasis. Existing outcome data are largely derived from tertiary centers, and real‐world data are lacking.
Shannon M. Vandriel +93 more
wiley +1 more source
Anales Médicos, 2023 Antecedentes: La colecistitis litiásica aguda es la complicación más frecuente de la litiasis vesicular y normalmente se acompaña de una elevación de las pruebas función hepática sin significar un riesgo de coledocolitiasis. Objetivo: Describir el comportamiento de las pruebas función hepática y su utilidad en la detección de coledocolitiasis en ...
Jael R. GarcÃa-Romo +2 more
openaire +2 more sources
Adições à Brioflora do Parque Estadual do Ibitipoca, Minas Gerais, Brasil
Revista de Biologia Neotropical, 2015 O presente estudo trata das briófitas do Parque Estadual do Ibitipoca, coletadas por diferentes pesquisadores e depositadas no Herbário Maria Eneyda P. Kauffmann Fidalgo (SP).
Olga Yano, Andrea Pereira Luizi-Ponzo
doaj +1 more source
Acta Botânica Brasílica, 2004 O trabalho refere-se à distribuição da brioflora ocorrente no cerrado Reserva Biológica e Estação Experimental de MogiGuaçu. Este bioma apresenta fisionomias que variam de florestas a campos.
Sandra Regina Visnadi
doaj +1 more source
Toward a clinical practice guide in pharmacogenomics testing for functional polymorphisms of drug-metabolizing enzymes. Gene/drug pairs and barriers perceived in Spain [PDF]
, 2012 The development of clinica lpractice recommendations or guidelines for the clinical use of biomarkers is an issue of great importance withr regard to adverse drug reactions.The poten-tial of pharmacogenomicbiomarkers has been extensively investigated in
Abad Santos, Francisco +18 more
core +4 more sources
Hoehnea, 2021 RESUMO O Parque Estadual de Itapeva (PEVA) é uma Unidade de Conservação de proteção integral, localizada no litoral norte do Estado do Rio Grande do Sul, cujo objetivo principal é a preservação de ecossistemas naturais de grande relevância ecológica e ...
Talita da Silva Dewes +2 more
doaj +1 more source
Current management of liver metastases from colorectal cancer: recommendations of the São Paulo Liver Club [PDF]
, 2013 Approximately half of patients with colorectal cancer present with liver metastases during the course of their disease, which directly affect prognosis and is responsible for two thirds of deaths related to the disease.
Coelho, Fabricio Ferreira +7 more
core +1 more source