Results 71 to 80 of about 57,998 (173)
MedComm, Volume 7, Issue 4, April 2026.Clinical utility of liquid biopsy‐based epigenetic profiling in PDAC management. Aberrant methylation of LAX1, RCAN3, and NR3C1 was identified in cfDNA from mPDAC patients, highlighting their potential as non‐invasive epigenetic biomarkers. Methylation levels of these genes showed prognostic value, supporting their relevance for patient stratification ...
Pablo Cano‐Ramírez +7 more
wiley +1 more source
Unveiling nuclear localization signals in human arginine deiminase proteins
Protein Science, Volume 35, Issue 4, April 2026.Abstract Arginine iminohydrolases are a family of enzymes involved in the conversion of arginine to citrulline. There are five isoforms in humans (PADI1, 2, 3, 4, and 6). Some of them are observed experimentally in the cytoplasm and in the nucleus of the cell; for moving to the latter location, they must pass through the cell nuclear membrane by using ...
José L. Neira +3 more
wiley +1 more source
Alimentary Pharmacology &Therapeutics, Volume 63, Issue 7, Page 955-966, April 2026.In the phase I/IIa GOING trial, an add‐on strategy with regorafenib followed by nivolumab showed a manageable safety profile and meaningful clinical activity in second‐line hepatocellular carcinoma, with a median overall survival of 25 months and 45% three‐year survival in sorafenib‐experienced patients.
Marco Sanduzzi‐Zamparelli +24 more
wiley +1 more source
Liver International, Volume 46, Issue 4, April 2026.ABSTRACT Metabolic dysfunction‐Associated Steatotic Liver Disease (MASLD) is a growing clinical challenge, necessitating effective diagnostic strategies to identify advanced liver fibrosis while minimising unnecessary referrals of mild cases. Current clinical guidelines recommend care pathways utilising non‐invasive tests (NITs) to stratify patients ...
Kirsi M. A. van Eekhout +16 more
wiley +1 more source
Aproximación al conocimiento de las briofitas de Venezuela [PDF]
, 1992 This paper introduces the up-dated taxonomic placement of 106 genera of Hepaticae and 233 genera of Musci known from Venezuela. Besides, a summarized version from the geographical distribution in Venezuela of 383 species of Hepaticae and 1009 species of ...
Moreno, Efraín J.
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Neurogastroenterology &Motility, Volume 38, Issue 4, April 2026.The Leuven Consensus provides a classification scheme for the diagnosis of pharyngeal and upper esophageal sphincter (UES) motor disorders using metrics derived from pharyngeal high‐resolution manometry‐impedance (P‐HRM‐I). These recommendations complement routine instrumental investigations and provide a standardized process, criteria, and ...
Taher I. Omari +25 more
wiley +1 more source
A brief history of the bryological exploration of the Azores [PDF]
, 2005 An account of the bryological activities on the Azores is given. Three phases can be distinguished: one at the end of the 19. century, when first collections of non-bryologists were made, which resulted in the discovery of less than one third of the ...
Frahm, Jan-Peter
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Psychological and Clinical Factors Mediate Post‐COVID‐19 Irritable Bowel Syndrome
Neurogastroenterology &Motility, Volume 38, Issue 4, April 2026.ABSTRACT Background Exposure to COVID‐19 has been shown previously to be associated with a higher risk for irritable bowel syndrome (IBS). This study aimed to better explain this relationship using mediation analysis. Methods This post hoc analysis of a multicenter cohort study includes 623 patients with and without COVID‐19 infection. All participants
Keren Hod +68 more
wiley +1 more source
Caldasia, 2001 An inventory of the understory and canopy of 4 ha oflower montane cloud forest at Monteverde, Costa Rica, yielded 190 bryophyte species: 133 hepatics, 56 mosses and 1 homwort. Thick branches of the lower canopy were by far the richest habitat in terms of
Gradstein S. Rob +3 more
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