Results 111 to 120 of about 2,602,393 (314)

Metronidazole‐Loaded Cyclodextrin Nanogels for Antibacterial Therapy and Microbiota Regulation in Periodontitis

open access: yesAdvanced Healthcare Materials, EarlyView.
A methacrylamide β‐cyclodextrin‐based nanogel (MACD nGel) is developed to load the antimicrobial drug Metronidazole (MNZ) for topical delivery for the treatment of periodontitis. It is demonstrated that cyclodextrin nanogel (nGel) loaded with metronidazole provides an efficient drug delivery route but also has potential clinical applications and offers
Yanjing Ji   +8 more
wiley   +1 more source

Quantitative Analysis of Expression Level of BCL2 and BAX Genes in Hep-2 and HL-60 Cells after Treatment with Etoposide

open access: yesActa Medica, 2008
Apoptotic cell death is a highly regulated process, which plays a crucial role in many biological events. The aim of the present research was to investigate the expression of the apoptosis related genes BCL2 and BAX in Hep-2 and HL- 60 cells.
Dita Královcová   +3 more
doaj   +1 more source

A Quantitative Printability Framework for Programmable Assembly of Pre‐Vascular Patterns via Laser‐Induced Forward Transfer

open access: yesAdvanced Healthcare Materials, EarlyView.
Laser‐Induced Forward Transfer (LIFT) is presented as a powerful micropatterning tool. An objective printability framework is developed to assess optimal printing parameter combinations. The technology is further explored for its ability to deterministically deposit microdroplets at predefined locations following CAD designs, enabling the patterning of
Cécile Bosmans   +8 more
wiley   +1 more source

Mechanism About How Piceatannol Enhances Anti-tumor Effect of Cisplatin on Laryngeal Cancer Hep-2 Cells

open access: yesZhongliu Fangzhi Yanjiu, 2018
Objective To investigate how piceatannol enhances the anti-tumor effect of cisplatin on laryngeal cancer cells and related molecular mechanism. Methods Laryngeal carcinoma Hep-2 cells were cultured in vitro and then treated with piceatannol and cisplatin.
DUAN Chuanxin
doaj   +1 more source

Self‐Assembling Peptide Hydrogels Support Stromal Vascular Fraction Viability to Promote In Vivo Nerve Regeneration

open access: yesAdvanced Healthcare Materials, EarlyView.
Stromal vascular fraction (SVF) may enhance nerve repair, especially when delivered in a self‐assembling peptide hydrogel (SAPH). In vitro, softer SAPH increased neuronal explant outgrowth and supported greater SVF viability and proliferation. In a rat sciatic defect, SVF in an optimized SAPH produced motor and sensory recovery equivalent to autograft ...
Liam A. McMorrow   +6 more
wiley   +1 more source

Inhibition of the RhoGTPase Cdc42 by ML141 enhances hepatocyte differentiation from human adipose-derived mesenchymal stem cells via the Wnt5a/PI3K/miR-122 pathway: impact of the age of the donor

open access: yesStem Cell Research & Therapy, 2018
Background Human adipose-derived mesenchymal stem cells (hADSCs) are promising cells that may promote hepatocyte differentiation (Hep-Dif) and improve liver function, but the involvement of Cdc42, a key small RhoGTPase which plays a crucial role in aging,
Diana Chaker   +6 more
doaj   +1 more source

On the Bekenstein-Hawking Entropy, Non-Commutative Branes and Logarithmic Corrections

open access: yes, 2006
We extend earlier work on the origin of the Bekenstein-Hawking entropy to higher-dimensional spacetimes. The mechanism of counting states is shown to work for all spacetimes associated with a Euclidean doublet $(E_1,M_1)+(E_2,M_2)$ of electric-magnetic ...
AXEL KRAUSE   +9 more
core   +1 more source

Characterization of an Injectable Poly(vinyl alcohol)‐gelatin Hydrogel for Growth Factor Delivery in an Orthopedic Application

open access: yesAdvanced Healthcare Materials, EarlyView.
This work introduces photo‐crosslinkable tyraminated poly(vinyl alcohol)‐gelatin (PVA‐GT) hydrogels as tunable injectable platforms for tissue engineering and growth factor delivery applications. This schematic illustrates the two developed hydrogel formulations and the experimental workflow used to evaluate their physico‐chemical properties in vitro ...
Alessia Longoni   +15 more
wiley   +1 more source

Motility provides specific adhesion patterns and improves Listeria monocytogenes invasion into human HEp-2 cells. [PDF]

open access: yesPLoS One, 2023
Abdulkadieva MM   +11 more
europepmc   +1 more source

Ti6Al4V‐Bioglass‐Copper Composites for Load‐Bearing Implants

open access: yesAdvanced Healthcare Materials, EarlyView.
We have designed and manufactured a novel Ti64‐based composite by adding 45S5 bioglass (BG) and copper (Cu). Adding BG on titanium improves wear resistance and biocompatibility, whereas Cu addition improves mechanical strength while providing inherent lifelong bacterial resistance.
Lochan Upadhayay   +3 more
wiley   +1 more source

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