Results 41 to 50 of about 28,532 (228)

EpCAM-targeting CAR-T cells against hepatoma cells in vitro

open access: yes陆军军医大学学报, 2023
Objective To investigate the killing efficacy of chimeric antigen receptor T (CAR-T) cells targeting epithelial cellular adhesion molecule (EpCAM) in several hepatoma cell lines.
WANG Song   +2 more
doaj   +1 more source

Synthesis of new simplified hemiasterlin derivatives with α,β-unsaturated carbonyl moiety.

open access: yes, 2014
International audienceIn this Letter, we report a convenient and efficient method for the synthesis of new simplified derivatives of hemiasterlin in which the α,α-dimethylbenzylic moiety A is replaced by α,β-unsaturated aryl groups as Michael acceptor ...
Doan, Duy Tien   +10 more
core   +3 more sources

Developmental Regulation of Rat Brain/Hep G2 Glucose Transporter Gene Expression [PDF]

open access: yesMolecular Endocrinology, 1989
The developmental regulation of rat brain-derived/Hep G2 glucose transporter gene expression was studied by means of Northern blot hybridization, using a rat brain glucose transporter cDNA probe, in order to directly quantify steady state glucose transporter mRNA levels.
H, Werner   +4 more
openaire   +2 more sources

Polyurethane Foam/Spheroid Culture System Using Human Hepatoblastoma Cell Line (Hep G2) as a Possible New Hybrid Artificial Liver

open access: yesCell Transplantation, 2001
The risk of xenozoonosis infections poses the greatest obstacle against the clinical application of hybrid artificial liver support system (HALSS). Primary human hepatocytes are an ideal source for HALSS, but the shortage of human livers available for ...
Yo-Ichi Yamashita M.D.   +10 more
doaj   +1 more source

Hepatitis B virus induces cell proliferation via HBx-induced microRNA-21 in hepatocellular carcinoma by targeting programmed cell death protein4 (PDCD4) and phosphatase and tensin homologue (PTEN). [PDF]

open access: yesPLoS ONE, 2014
Hepatitis B viral infection-induced hepatocellular carcinoma is one of the major problems in the developing countries. One of the HBV proteins, HBx, modulates the host cell machinery via several mechanisms. In this study we hypothesized that HBV enhances
Preeti Damania   +7 more
doaj   +1 more source

Impact of Growing Location on Kakadu Plum Fruit Composition and In Vitro Bioactivity as Determinants of Its Nutraceutical Potential

open access: yesNutraceuticals, 2022
Growing location is known to affect the metabolite content and functionality of wild harvested fruits. Terminalia ferdinandiana, commonly known as Kakadu plum (KP), is among the most commercially important native Australian bush foods.
Eshetu M. Bobasa   +6 more
doaj   +1 more source

Anti-Metastatic Activity of Tagitinin C from Tithonia diversifolia in a Xenograft Mouse Model of Hepatocellular Carcinoma

open access: yesLivers, 2022
Sesquiterpenoid tagitinin C, present in Tithonia diversifolia leaves, has been known to have anti-hepatoma properties. Therefore, we investigated the anti-metastatic potential of tagitinin C in xenograft models of hepatocellular carcinoma (HCC).
Chuan-Yi Lin   +6 more
doaj   +1 more source

Cytotoxicity and structure-activity relationships of xanthone derivatives from Mesua beccariana, Mesua ferrea and Mesua congestiflora towards nine human cancer cell lines. [PDF]

open access: yes, 2013
The cytotoxic structure-activity relationships among a series of xanthone derivatives from Mesua beccariana, Mesua ferrea and Mesua congestiflora were studied. Eleven xanthone derivatives identified as mesuarianone (1), mesuasinone (2), mesuaferrin A (3),
Gwendoline Cheng   +5 more
core   +3 more sources

Copper overload affects copper and iron metabolism in Hep-G2 cells

open access: yesAmerican Journal of Physiology-Gastrointestinal and Liver Physiology, 2004
Divalent metal transporter #1 (DMT1) is responsible for intestinal nonheme Fe apical uptake. However, DMT1 appears to have an additional function in Cu transport in intestinal cells. Because the liver has an essential role in body Cu homeostasis, we examined the potential involvement of Cu in the regulation of DMT1 expression and activity in Hep-G2 ...
Arredondo, M   +6 more
openaire   +8 more sources

Anti-Proliferative Effect of Camellianin A in Adinandra nitida Leaves and Its Apoptotic Induction in Human Hep G2 and MCF-7 Cells

open access: yesMolecules, 2010
Leaves of Adinandra nitida constitute a kind of flavonoid-rich plant food. In this study, camellianin A, the main flavonoid in the leaves of Adinandra nitida,was prepared and identified by high performance liquid chromatography-photodiode array detector ...
Han Gao   +3 more
doaj   +1 more source

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