Results 161 to 170 of about 96,473 (194)

Tanshinone IIA inhibits heat-induced growth of p53-mutant Huh-7 hepatocellular carcinoma by modulating osmotic homeostasis and glycolysis through targeting ALDH7A1. [PDF]

Cell Death Discov
Li H, Ju S, Wang J, Kuang D, Chen P, Zhang M, Qian R, Liang C, Han D, Duan X.   +9 more
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Lactylation-driven MVP upregulation boosts immunotherapy resistance by inhibiting PD-L1 degradation in hepatocellular carcinoma. [PDF]

J Immunother Cancer
Liu S, Pan Y, Liu W, Bu X, Shao R, Wang Q, Wu J, Wu C, Hu W, Xu J, Wu C, Jiang J.   +11 more
europepmc   +1 more source

Correction: Frequent loss-of-function mutations in the AMPK-α2 catalytic subunit suggest a tumour suppressor role in human skin cancers. [PDF]

Biochem J
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Vrednotenje citotoksičnosti izbranih zaviralcev topoizomeraz na celicah HEP G2

, 2018
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Endogenous forms of fibrinogen in hep g2 cells

Thrombosis Research, 1987
The three polypeptide chains of fibrinogen, A alpha, B beta and gamma chain, are synthesized on separate polysomes. Fully formed fibrinogen is a six chain, disulfide-linked, dimeric molecule with a molecular weight of 340kDa. Previous pulse-chase studies with L-35 S methionine using the human hepatocellular carcinoma cell line, Hep-G2, showed that the ...
Sharon Yu, Victoria Kong, Bohdan Kudryk, Colvin Redman, Lindsley F. Kimball   +4 more
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Lipid and lipoprotein metabolism in Hep G2 cells

Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism, 1988
Lipid composition, lipid synthesis and lipoprotein secretion by the Hep G2 cell line have been studied with substrate and insulin supplied under different conditions. The lipid composition of Hep G2 cells was close to that of normal human liver, except for a higher content in sphingomyelin (P less than 0.005) and a lower phosphatidylcholine ...
S R, Wang, M, Pessah, J, Infante, D, Catala, C, Salvat, R, Infante   +5 more
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Drug metabolism by the human hepatoma cell, Hep G2

Biochemical and Biophysical Research Communications, 1987
The human liver-derived cell line, Hep G2, has aryl hydrocarbon hydroxylase and 7-ethoxycoumarin o-de-ethylase activities. Partial purification of cytochrome P-450 from Hep G2 cells provided spectral evidence of this hemeprotein in the purified fraction.
S, Sassa, O, Sugita, R A, Galbraith, A, Kappas   +3 more
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Cyclosporin A inhibits mitochondrial biogenesis in Hep G2 cells

Biochemical and Biophysical Research Communications, 2018
Dysregulation of mitochondrial biogenesis is associated with pathogenesis in many diseases, including liver diseases. Cyclosporine A (CsA), one of the most commonly used drug to treat many autoimmune diseases and to prevent allograft rejection after organ transplantation, has been reported to cause mitochondrial dysfunction.
Rui, Qi, Dongtao, Wang, Lifei, Xing, Zhongjun, Wu   +3 more
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Bidirectional membrane transport of intact glutathione in Hep G2 cells

American Journal of Physiology-Gastrointestinal and Liver Physiology, 1993
Rat hepatocytes exhibit bidirectional carrier-mediated transport of reduced glutathione (GSH) across the plasma membrane. Transport of GSH has not been well characterized in human-derived cells. We examined Hep G2 cells as a possible human liver model for GSH homeostasis. Hep G2 cell GSH averaged 25.9 +/- 1.4 nmol/10(6) cells.
G, Sze, N, Kaplowitz, M, Ookhtens, S C, Lu   +3 more
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