Results 181 to 190 of about 96,473 (194)

The glycosphingolipid composition of the human hepatoma cell line, Hep-G2

Archives of Biochemistry and Biophysics, 1989
The origin of plasma glycosphingolipids in normal individuals and the mechanisms by which tumor-associated glycosphingolipid antigens enter the plasma in patients with cancer are largely unknown. The Hep-G2 human hepatoma cell line retains many of the characteristics of differentiated hepatocytes including the ability to synthesize and secrete ...
P F, Spitalnik, J M, Danley, S R, Burger, S L, Spitalnik   +3 more
openaire   +2 more sources

Characterization of glutathione efflux from Hep G2 cells.

Research communications in molecular pathology and pharmacology, 1995
Previous studies have suggested that both cAMP-dependent signal transduction pathway and Ca2+/protein kinase C-dependent pathway are involved in GSH efflux from hepatocytes. In the present study, GSH efflux from Hep G2 cells, a human-derived hepatoma cell line, was further characterized.
J H, Liu, H, Miyakawa, J, Liu, K, Mori, T, Takano, F, Marumo, C, Sato   +6 more
openaire   +1 more source

Mifepristone potentiates etoposide toxicity in Hep G2 cells by modulating drug transport

Toxicology in Vitro, 2019
Etoposide is a well-known and widely used anticancer drug that displays several side effects. In addition, tumors often acquire resistance to this drug. Our aim is to develop a combination therapy that would augment toxicity of etoposide in malignant cells.
Z. Dostál, P. Kosina, P. Mlejnek, K. Kikalová, M. Modrianský   +4 more
openaire   +2 more sources

Human liver-derived HEP G2 cells produce functional properdin.

The Journal of laboratory and clinical medicine, 1995
Properdin stabilizes the alternative complement pathway C3 convertase and is synthesized by monocytes and myelomonocytic cell lines. Hepatic production of properdin has never been documented, although most other complement components are synthesized by liver.
K K, Maves, J M, Weiler
openaire   +1 more source

Testosterone metabolism in human hepatoma (Hep-G2) cells

Biochemical Society Transactions, 1990
A P, Stubbs, S E, Edmunds, G M, Murphy, M L, Wilkinson   +3 more
openaire   +2 more sources

Hep G2 is a hepatoblastoma-derived cell line

Human Pathology, 2009
Dolores, López-Terrada, Sau Wai, Cheung, Milton J, Finegold, Barbara B, Knowles   +3 more
openaire   +2 more sources

Rat Brain/Hep G2 Glucose Transporter Gene Expression in Brain

1992
Publisher Summary This chapter presents a methodology to quantitate Glut-1 mRNA and protein levels in the brain and in neuronal and astroglial cells in primary culture. Measurement of Glut-1 mRNA levels include isolation of total RNA, cDNA probe preparation, Northern blotting, and hybridization.
Mohan K. Raizada, Bartosz Z. Rydzewski, Haim Werner, Brian A. Masters, Charles T. Roberts, Derek LeRoith   +5 more
openaire   +1 more source

POLYAMINE METABOLISM IN HUMAN HEPATOCELLULAR CANCER CELLS (Hep - G2)

Biochemical Society Transactions, 1994
A A, Santos, A P, Stubbs, M, Maghsoudloo, G M, Murphy, M L, Wilkinson   +4 more
openaire   +2 more sources

Effects of cadmium on glutathione metabolism in Hep G2 cells.

Research communications in molecular pathology and pharmacology, 1996
Effects of cadmium on hepatic glutathione (GSH) metabolism were characterized in a human-derived hepatoma cell line, Hep G2 cells. Intracellular GSH concentrations were significantly increased after incubation with cadmium at 5 and 10 microM for 24 and 48 hr.
J H, Liu, H, Miyakawa, T, Takano, F, Marumo, C, Sato   +4 more
openaire   +1 more source

Iron transport and subcellular distribution in Hep G2 hepatocarcinoma cells.

Annals of clinical and laboratory science, 1995
Thalassemic patients with iron overload are presently treated with deferoxamine or the experimental chelator deferiprone. To understand how these agents remove iron from the liver, cultured human hepatoma cells loaded with iron were previously used as a model for hepatic iron overload.
J G, Parkes, D M, Templeton
openaire   +1 more source