Results 21 to 30 of about 96,473 (194)

Ethanol Metabolism Results in A G2/M Cell–Cycle Arrest in Recombinant Hep G2 Cells [PDF]

Hepatology, 2003
Previous studies using the Hep G2–based VA cells showed that ethanol metabolism resulted in both cytotoxicity and impaired DNA synthesis, causing reduced accumulation of cells in culture. To further characterize the ethanol oxidation–mediated impairment of DNA synthesis we analyzed the cell–cycle progression of VA cells. These
Dahn L, Clemens, Lilian E, Calisto, Michael F, Sorrell, Dean J, Tuma   +3 more
openaire   +2 more sources

Identification of lipid derivatives in Hep G2 cells.

Acta Biochimica Polonica, 1970
Metabolism of polyunsaturated fatty acids results in biosynthesis of mediators with different physiological effects. These metabolites include prostaglandins, prostacyclins, isoprostanes and others that are important signalling molecules and regulate a variety of physiological and pathophysiological processes including inflammation.
Gdula-Argasińska, Joanna, Garbacik, Aneta, Tyszka-Czochara, Małgorzata, Woźniakiewicz, Michał, Paśko, Paweł, Czepiel, Jacek   +5 more
openaire   +4 more sources

Synthesis, docking study, and structure activity relationship of novel anti-tumor 1, 2, 4 triazole derivatives incorporating 2-(2, 3- dimethyl aminobenzoic acid) moiety [PDF]

Pharmacia, 2022
A series of 1,2,4 triazole derivatives (H7-12) have been synthesized by reacting an excess of hydrazine hydrate with carbothioamide derivatives (H1-6).
Hiba Alsaad, Ammar Kubba, Lubna H. Tahtamouni, Ali H. Hamzah   +3 more
doaj   +3 more sources

Chemical composition, antioxidant and alpha-Glucosidase-Inhibiting activities of the aqueous and hydroethanolic extracts of Vaccinium myrtillus Leaves [PDF]

, 2017
Vaccinium myrtillus (bilberry) leaf is traditionally used in southeastern Europe for the treatment of diabetes. In the present study, the ability of bilberry leaf extracts to inhibit carbohydrate-hydrolyzing enzymes and restore glutathione concentration ...
Bljajic, Kristina, Cacic, Ana, de Carvalho, Isabel Saraiva, Jablan, Jasna, Koncic, Marijana Zovko, Petlevski, Roberta, Sostaric, Nina, Vujic, Lovorka   +7 more
core   +1 more source

Stevia: limiting cholesterol synthesis in Hep-G2 cells

Asia Pacific Journal of Molecular Biology and Biotechnology, 2020
As of today, no literature has been reported on the efficacy of stevia on lipid regulations conducted in vitro. Thus, the current study was focusing on the potential of Stevia rebaudiana bertoni as an anti-hypercholesterolemia substitute in limiting the de novo cholesterol synthesis in Hep-G2 cell line.
Ilias, Amirul Nazhan, Hamzah, Hazilawati, Ismail, Intan Safinar, Ajat, Mokrish   +3 more
openaire   +1 more source

Synthesis of new bioisosteric hemiasterlin analogues with extremely high cytotoxicity [PDF]

, 2014
International audienceIn this article, we report a convenient and efficient method for the synthesis of new simplified derivativesof hemiasterlin in which the α,α-dimethylbenzylic moiety A is replaced by α,β-unsaturated aryl groupsas Michael acceptor ...
Doan, Duy Tien, Hoang, Thi Phuong, Jean, Mickael, Ngo, Quoc Anh, Nguyen Van, Tuyen, The, Chinh Pham, Thi, Tham Pham, Thi, Thu Ha Nguyen, Thi, Thu Ha Vu, Thi, Tuyet Anh Dang, van de Weghe, Pierre   +10 more
core   +3 more sources

Antitumor immunity and therapeutic properties of marine seaweeds-derived extracts in the treatment of cancer

Cancer Cell International, 2022
Marine seaweeds are important sources of drugs with several pharmacological characteristics. The present study aims to evaluate the antitumor and antitumor immunological potentials of the extracts from the brown alga Padina pavonica and the red alga ...
Mostafa M. El-Sheekh, Mohamed Nassef, Eman Bases, Shimaa El Shafay, Rania El-shenody   +4 more
doaj   +1 more source

Fully Off-shell Effective Action and its Supersymmetry in Matrix Theory [PDF]

, 2001
As a step toward clarification of the power of supersymmetry (SUSY) in Matrix theory, a complete calculation, including all the spin effects, is performed of the effective action of a probe D-particle, moving along an arbitrary trajectory in interaction ...
Banks T, Bigatti D, de Wit B, Flume R, Kazama Y, Kazama Y, Konechny A, Lowe D A, Nicolai H, Paban S, Sen A, Sethi S, Susskind L, T Muramatsu, Taylor W, Taylor W, Y Kazama   +16 more
core   +7 more sources

Differentiation Effects by the Combination of Spheroid Formation and Sodium Butyrate Treatment in Human Hepatoblastoma Cell Line (Hep G2): A Possible Cell Source for Hybrid Artificial Liver

Cell Transplantation, 2005
The aim of this study was to investigate the feasibility of human hepatoblastoma cell line (Hep G2), which differentiates by spheroid formation, and treatment with sodium butyrate (SB) as a cell source for hybrid artificial liver (HAL).
J. Fukuda, K. Okamura, K. Ishihara, H. Mizumoto, K. Nakazawa, H. Ijima, T. Kajiwara, K. Funatsu Ph.D.   +7 more
doaj   +1 more source

Parameters of cholesterol metabolism in the human hepatoma cell line, Hep-G2.

Journal of Lipid Research, 1988
The human hepatoma cell line Hep-G2 has been shown to express the major enzymes of intra- and extracellular cholesterol metabolism. These include lecithin:cholesterol acyltransferase, acyl coenzyme A:cholesterol acyltransferase, 3-hydroxy-3 ...
S K Erickson, P E Fielding
doaj   +1 more source