Results 61 to 70 of about 96,473 (194)

SiC nanoparticles cyto- and genotoxicity to Hep-G2 cells

Journal of Physics: Conference Series, 2009
While emerging nanotechnologies have seen significant development in recent years, knowledge on exposure levels as well as data on toxicity of nanoparticles are still quite limited. Indeed, there is a general agreement that development of nanotechnologies may lead to considerable dissemination of nanoparticles in the environment.
Barillet, S., Jugan, M.-L., Simon-Deckers, A., Leconte, Y., Herlin-Boime, Nathalie, Mayne-L'Hermite, M., Reynaud, C., Carrière, M.   +7 more
openaire   +2 more sources

Phorbol ester inhibits erythropoietin production in human hepatoma cells (Hep G2) [PDF]

American Journal of Physiology-Cell Physiology, 1992
Using the human hepatoma cell line Hep G2, we have studied a possible role of protein kinase C (PKC) activity for regulation of erythropoietin (EPO) production. During a 72-h incubation, EPO production by the cells was stimulated sevenfold by exposure to low oxygen tension (1%) and threefold by exposure to cobaltous chloride (100 microM).
Kurtz, Armin, Eckardt, K. U., Pugh, C., Corvol, P., Fabbro, D., Ratcliffe, P.   +5 more
openaire   +4 more sources

Halorotetin B, A Novel Terpenoid Compound Derived from Marine Ascidian, Suppresses Tumor Growth by Targeting the Cell Cycle Regulator UBE2C

Advanced Science, EarlyView.
Halorotetin B, a novel small‐molecule terpenoid identified from an edible marine ascidian, exhibits strong anti‐tumor activity both in vitro and in vivo through direct targeting UBE2C to induce tumor cell cycle arrest and then lead tumor cell senescence. As a newly discovered UBE2C inhibitor, Halorotetin B can serve as a novel potential cell senescence
Shanhao Han, Jianhui Li, Yuting Zhu, Penghui Liu, Yaoyao Zheng, Muchun He, Bo Dong   +6 more
wiley   +1 more source

Addressing Oxygen Embrittlement in Additively Manufactured Titanium via Cu‐Mediated Interstitial Site Engineering

Advanced Science, EarlyView.
A novel “Cu‐mediated interstitial site engineering” strategy is introduced to thermodynamically stabilize hexagonal oxygen (hex‐O) configurations in oxygen‐containing titanium alloys. The hex‐O configuration activates multiple slip systems and enhances dislocation pinning via long‐range repulsion.
Xiaobin Lin, Xudong Rong, Jiachen Xie, Xinru Wang, Jianteng Wang, Zhihang Xu, Dongdong Zhao, Shiwei Pan, Feng Qian, Longlong Ma, Gang Sha, Xiang Zhang, Chunsheng Shi, Chunnian He, Naiqin Zhao   +14 more
wiley   +1 more source

Redox‐Programmed Activation of a Dual‐Modal Probe for High‐Fidelity Tumor Delineation and Image‐Guided Surgery

Advanced Science, EarlyView.
This study presents a glutathione (GSH)‐activatable dual‐modality probe (GAP9) with a redox‐tuned activation window for precise tumor detection. It remains quenched (“OFF”) in normal tissue yet activates specifically in tumors for T1‐weighted magnetic resonance imaging (MRI) preoperative mapping and near‐infrared II (NIR‐II) fluorescence intraoperative
Haohao Yan, Yanbin Feng, Qian Jia, Ruili Zhang, Zhongliang Wang   +4 more
wiley   +1 more source

²²⁵Ac-rHDL Nanoparticles: A Potential Agent for Targeted Alpha-Particle Therapy of Tumors Overexpressing SR-BI Proteins

Molecules, 2022
Actinium-225 and other alpha-particle-emitting radionuclides have shown high potential for cancer treatment. Reconstituted high-density lipoproteins (rHDL) specifically recognize the scavenger receptor B type I (SR-BI) overexpressed in several types of ...
Tania Hernández-Jiménez, Guillermina Ferro-Flores, Enrique Morales-Ávila, Keila Isaac-Olivé, Blanca Ocampo-García, Liliana Aranda-Lara, Clara Santos-Cuevas, Myrna Luna-Gutiérrez, Laura De Nardo, Antonio Rosato, Laura Meléndez-Alafort   +10 more
doaj   +1 more source

New G_2 metric, D6-branes and Lattice Universe

, 2002
We construct a new (singular) cohomogeneity-three metric of G_2 holonomy. The solution can be viewed as a triple intersection of smeared Taub-NUTs. The metric comprises three non-compact radial-type coordinates, with the principal orbits being a T^3 ...
Acharya, Acharya, Atiyah, Atiyah, Behrndt, Brandhuber, Brandhuber, Bryant, Chong, Cvetič, Cvetič, Cvetič, Cvetič, Cvetič, Cvetič, Cvetič, Cvetič, Cvetič, Duff, Einasto, Einasto, Gibbons, Gibbons, Gukov, H. Lü, Hernandez, Hitchin, Kirshner, Lavrinenko, Nergiz, Papadopoulos, Witten   +31 more
core   +2 more sources

Histopathologic Analysis of the Morpho‐Functional Zones of the Human Acetabular Labrum

Clinical Anatomy, EarlyView.
ABSTRACT The structural and functional adaptation of soft tissues to mechanical load controls their ability to withstand injury and influences their capacity for healing. Similar to the knee meniscus, the acetabular labrum exhibits zonal differences in mechanical load distribution, resulting in distinct regions with unique structural and functional ...
Abdulaziz A. Alomiery, Andrew C. Hall, Thomas H. Gillingwater, Afaf Alsolami, Abduelmenem Alashkham   +4 more
wiley   +1 more source

Singular 7-manifolds with G_2 holonomy and intersecting 6-branes

, 2002
A 7-manifold with G_2 holonomy can be constructed as a R^3 bundle over a quaternionic space. We consider a quaternionic base space which is singular and its metric depends on three parameters, where one of them corresponds to an interpolation between S^4
Acharya, Acharya, Acharya, Acharya, Alekseevsky, Alekseevsky, Atiyah, Atiyah, Bagger, Beasley, Behrndt, Behrndt, Behrndt, Bilal, Blumenhagen, Blumenhagen, Bousso, Brandhuber, Brown, Bryant, Casteill, Casteill, Curio, Cvetič, Cvetič, Cvetič, Cvetič, Cvetič, D'Auria, de Wit, de Wit, de Wit, de Wit, Duff, Friedmann, Fubini, Gibbons, Gibbons, Gukov, Gunaydin, Hernandez, Hernandez, Ita, Kallosh, Klaus Behrndt, Kramer, Liu, London, Papadopoulos, Townsend, Townsend, Witten, Wolf   +52 more
core   +1 more source

Quark-Monopole Potentials in Large N Super Yang-Mills [PDF]

, 1998
We compute the quark-monopole potential for ${\cal N}=4$ super Yang-Mills in the large $N$ limit. We find an attractive potential that falls off as 1/L and is manifestly invariant under $g\to 1/g$.
Minahan, Joseph A.
core   +2 more sources