Results 11 to 20 of about 35,933 (220)
Apoptosis induction on human hepatoma cells Hep G2 of decabrominated diphenyl ether (PBDE-209) [PDF]
Toxicology Letters, 2007 Polybrominated diphenyl ethers (PBDEs) are an important class of halogenated organic brominated flame retardants. Because of their presence in abiotic and biotic environments widely and their structural similarity to polychlorinated biphenyls (PCBs ...
Hu, De-Cong +5 more
core +3 more sources
Human papillomavirus type 18 E6 and E7 genes integrate into human hepatoma derived cell line Hep G2. [PDF]
PLoS ONE, 2012 BACKGROUND AND OBJECTIVES: Human papillomaviruses have been linked causally to some human cancers such as cervical carcinoma, but there is very little research addressing the effect of HPV infection on human liver cells.
Tianzhong Ma +10 more
doaj +1 more source
Soy Protein Peptides Regulate Cholesterol Homeostasis in Hep G2 Cells [PDF]
The Journal of Nutrition, 2000 The activation of LDL receptors was described recently in a human hepatoma cell line (Hep G2) exposed both to alpha + alpha' subunits from 7S soy globulin and to Croksoy(R)70, a commercial isoflavone-poor soy concentrate. To assess the final identity of the peptide(s) putatively responsible for the biochemical effect, experiments were performed in Hep ...
M.R. Lovati +6 more
openaire +3 more sources
EpCAM-targeting CAR-T cells against hepatoma cells in vitro
陆军军医大学学报, 2023 Objective To investigate the killing efficacy of chimeric antigen receptor T (CAR-T) cells targeting epithelial cellular adhesion molecule (EpCAM) in several hepatoma cell lines.
WANG Song +2 more
doaj +1 more source
Ethanol Metabolism Results in A G2/M Cell–Cycle Arrest in Recombinant Hep G2 Cells [PDF]
Hepatology, 2003 Previous studies using the Hep G2–based VA cells showed that ethanol metabolism resulted in both cytotoxicity and impaired DNA synthesis, causing reduced accumulation of cells in culture. To further characterize the ethanol oxidation–mediated impairment of DNA synthesis we analyzed the cell–cycle progression of VA cells. These
Dahn L, Clemens +3 more
openaire +2 more sources
Synthesis, docking study, and structure activity relationship of novel anti-tumor 1, 2, 4 triazole derivatives incorporating 2-(2, 3- dimethyl aminobenzoic acid) moiety [PDF]
Pharmacia, 2022 A series of 1,2,4 triazole derivatives (H7-12) have been synthesized by reacting an excess of hydrazine hydrate with carbothioamide derivatives (H1-6).
Hiba Alsaad +3 more
doaj +3 more sources
Cancer Cell International, 2022 Marine seaweeds are important sources of drugs with several pharmacological characteristics. The present study aims to evaluate the antitumor and antitumor immunological potentials of the extracts from the brown alga Padina pavonica and the red alga ...
Mostafa M. El-Sheekh +4 more
doaj +1 more source
Plants, 2023 An aqueous extract of Syzygium cumini seeds was utilized to green synthesize titanium dioxide nanoparticles (TiO2 NPs). UV-Visible, DLS, FTIR, XRD, FESEM, TEM, SAED, EDAX, and photoluminescence spectroscopy techniques were employed to characterize the ...
Musaed Rayzah +11 more
doaj +1 more source
PLoS ONE, 2015 Arctigenin (ARG) has been previously reported to exert high biological activities including anti-inflammatory, antiviral and anticancer. In this study, the anti-tumor mechanism of ARG towards human hepatocellular carcinoma (HCC) was firstly investigated.
Zheng Lu +5 more
doaj +1 more source
Pharmaceutics, 2022 The limitations of gemcitabine (GEM) in cancer therapy are due to its poor pharmacokinetics, which cause undesired adverse effects. The current study was aimed at investigating the anticancer effect and apoptotic mechanism of synthesized nanoemulsion (NE)
Sahar M. AlMotwaa, Waad A. Al-Otaibi
doaj +1 more source