Results 41 to 50 of about 1,743 (121)

Serum Metabolomics of Patients with Hepatic Cystic Echinococcosis

Biomedical Chromatography, Volume 39, Issue 10, October 2025.
ABSTRACT Hepatic cystic echinococcosis (HCE), a liver manifestation of hydatid disease, is among the 17 neglected tropical diseases (NTDs) prioritized by the WHO for eradication by 2025. Although imaging and serological tests are currently the main diagnostic approaches for HCE, they have notable limitations in sensitivity and specificity.
Yisimayili Aimaiti, Kahaer Tuerxun, Yuan‐Quan Wu, Abudoukeyimu Yasheng, Irshat Ibrahim, Qi‐Lin Xu, Muzaipaer Muhetajiang, Tuerganaili Aji   +7 more
wiley   +1 more source

Pulmonary Hydatid Cyst Mimicking Both Tuberculous Cavity and Aspergilloma: A Diagnostic Challenge in an Endemic Region

Clinical Case Reports, Volume 13, Issue 10, October 2025.
ABSTRACT Cystic echinococcosis (CE), caused by Echinococcus granulosus, is a zoonotic disease endemic in many pastoral regions. Pulmonary involvement, although less common than hepatic, may present with nonspecific respiratory symptoms and mimic other pathologies such as tuberculosis, posing a diagnostic challenge.
Mohammad Alaa Aldakak, Aows Ahmad, Raneem Ahmad, Bassel Ibrahim, Yehia Taifour   +4 more
wiley   +1 more source

Magnetic Resonance Imaging Features of Hepatic Hydatid Disease: A Pictorial Review with Emphasis on Atypical Presentations and Differential Diagnosis

Diagnostics
Hepatic echinococcosis, caused by Echinococcus species, remains a significant global health concern, with cystic echinococcosis (CE) being widespread and alveolar echinococcosis (AE) representing a rarer but more aggressive form.
Jelena Djokic Kovač, Aleksandra Đikić-Rom, Aleksandra Janković, Nikica Grubor, Aleksandra Đurić-Stefanović, Aleksandar Bogdanović, Milica Mitrović, Ognjan Skrobić, Andrija Antić, Đorđe Knežević, Goran Đuričić, Predrag Zdujić, Nemanja Bidžić   +12 more
doaj   +1 more source

Spatiotemporal Transcriptomic Profiling Reveals the Dynamic Immunological Landscape of Alveolar Echinococcosis

Advanced Science, Volume 12, Issue 18, May 15, 2025.
An unprecedented high‐resolution spatial atlas of the E. multilocularis infection foci is obtained, revealing the dynamic functions of neutrophils, Spp1+ macrophages, and fibroblasts during disease progression. The transition of parasite control strategy from “active killing” to “negative segregation” by the host may provide instructive insights into ...
Zhihua Ou, Li Li, Peidi Ren, Ting‐Ting Zhou, Fan He, Jialing Chen, Huimin Cai, Xiumin Han, Yao‐Dong Wu, Jiandong Li, Xiu‐Rong Li, Qiming Tan, Wenhui Li, Qi Chen, Nian‐Zhang Zhang, Xiuju He, Wei‐Gang Chen, Yanping Zhao, Jiwen Sun, Qian Zhang, Yan‐Tao Wu, Yingan Liang, Jie You, Guohai Hu, Xue‐Qi Tian, Sha Liao, Bao‐Quan Fu, Ao Chen, Xue‐Peng Cai, Huanming Yang, Jian Wang, Xin Jin, Xun Xu, Wan‐Zhong Jia, Junhua Li, Hong‐Bin Yan   +35 more
wiley   +1 more source

Can contrast-enhanced ultrasound differentiate the type of hepatic echinococcosis: cystic echinococcosis or alveolar echinococcosis?

Parasites & Vectors, 2023
Background Hepatic echinococcosis (HE) is a zoonotic disease caused by Echinococcus, and Echinococcus granulosus and E. multilocularis are the most common, causing cystic echinococcosis (CE) and alveolar echinococcosis (AE), respectively.
Xuhui Zhang, Lamu Suolang, Yelei Ren, Yifei Wang, Yong Jiang, Xiaofei Zhong, Zehui Gou, Wu Zhou, Juan Chen, Yongzhong Li, Diming Cai   +10 more
doaj   +1 more source

Spatiotemporal Transcriptomic Profiling Reveals the Dynamic Immunological Landscape of Alveolar Echinococcosis (Adv. Sci. 18/2025)

Advanced Science, Volume 12, Issue 18, May 15, 2025.
Echinococcus Multilocularis In article number 2405914, Wan‐Zhong Jia, Junhua Li, Hong‐Bin Yan, and co‐workers decipher the shift in host (Nezha) immune response strategies from “active killing” to “negative segregation” during Echinococcus multilocularis hepatic infection.
Zhihua Ou, Li Li, Peidi Ren, Ting‐Ting Zhou, Fan He, Jialing Chen, Huimin Cai, Xiumin Han, Yao‐Dong Wu, Jiandong Li, Xiu‐Rong Li, Qiming Tan, Wenhui Li, Qi Chen, Nian‐Zhang Zhang, Xiuju He, Wei‐Gang Chen, Yanping Zhao, Jiwen Sun, Qian Zhang, Yan‐Tao Wu, Yingan Liang, Jie You, Guohai Hu, Xue‐Qi Tian, Sha Liao, Bao‐Quan Fu, Ao Chen, Xue‐Peng Cai, Huanming Yang, Jian Wang, Xin Jin, Xun Xu, Wan‐Zhong Jia, Junhua Li, Hong‐Bin Yan   +35 more
wiley   +1 more source

A Large Retroperitoneal Hydatid Cyst: A Cause of Recurrence and What to Consider in Their Management

Case Reports in Infectious Diseases, Volume 2025, Issue 1, 2025.
Retroperitoneal hydatid cyst caused by Echinococcus granulosus is a rare clinical condition that can occur primarily or synchronously with other location. We present a 47‐year‐old man with a recurrent retroperitoneal echinococcal cyst, complaining of pain in the right lumbar region.
Svetlana Shumarova, Manol Sokolov, Piyush Baindara   +2 more
wiley   +1 more source

Histopathological assessment of the viability of hepatic alveolar echinococcosis

Histopathology, Volume 85, Issue 6, Page 857-867, December 2024.
Decay of Echinococcosis multilocularis was analysed and haematoxylin and eosin (H&E)‐based histological criteria for viability assessment were defined. Subsequently, the use of mAbEm18, a well‐established serological viability marker, was validated for immunohistochemistry, revealing that mAbEm18‐immunohistochemistry (IHC) is also reliable for ...
Selina Robers, Michael Reinehr, Lillemor Haibach, Eva Furrer, Annina Cincera, Philipp Andreas Kronenberg, Ramon Marc Eichenberger, Peter Deplazes, Ansgar Deibel, Beat Müllhaupt, Achim Weber   +10 more
wiley   +1 more source

Contradictory Role of Gadd45β in Liver Diseases

Journal of Cellular and Molecular Medicine, Volume 28, Issue 23, December 2024.
ABSTRACT There are three homologous proteins (α, β and γ) in the growth arrest and DNA damage 45 (Gadd45) family. These proteins act as cellular responders to physiological and environmental stimuli. Gadd45β plays a significant role in the pathogenesis of liver diseases. Liver injury and growth stimulation increase expression of Gadd45β, which promotes
Chi Wu, Xiaozhen Song, Miaoxin Zhang, Longjun Yang, Panpan Lu, Qiang Ding, Mei Liu   +6 more
wiley   +1 more source

Unveiling the promise: Exosomes as game‐changers in anti‐infective therapy

Exploration, Volume 4, Issue 5, October 2024.
A comprehensive review to reveal new insights into exosomes’ distinctiveness, the growing availability of new analytical tools that drive the development of next‐generation synthetic systems were presented. Herein, light is shed on exosomes as drug delivery vehicles in anti‐infective therapy.
Vivek P. Chavda, Guanghong Luo, Rajashri Bezbaruah, Tutumoni Kalita, Anupam Sarma, Gitima Deka, Yanhong Duo, Bhrigu Kumar Das, Yesha Shah, Humzah Postwala   +9 more
wiley   +1 more source