Results 201 to 210 of about 229,203 (309)

Spatial multi‐omics identifies a NOTCH3‐mediated capillary–mCAF crosstalk driving immune exclusion in hepatocellular carcinoma

iMeta, EarlyView.
Spatial multi‐omics defines a DLL4–NOTCH3–driven capillary–mCAF axis orchestrating fibrotic remodeling and immune exclusion in hepatocellular carcinoma tumor cores, conferring immune checkpoint blockade resistance. Targeting stromal NOTCH3 disrupts this pro‐fibrotic niche, enhances T cell infiltration, and synergizes with anti‐PD‐1 therapy ...
Fansen Ji, Haochen Li, Qi Wang, Xiaojuan Wang, Jiawei Zhang, Ying Xiao, Huan Li, Hao Liu, Tanqing Long, Boyang Wu, Hao Chen, Haoming Xia, Xinquan Liu, Chuanrui Xu, Yibo Gao, Bingjun Tang, Juan Liu, Shizhong Yang, Jiahong Dong   +18 more
wiley   +1 more source

A novel method using the level of mobility to predict mortality in patients admitted for decompensated cirrhosis: A prospective study

, 2022
Liver Transplantation, EarlyView.
Andrew J. Groff, Marina Serper, Sunny Y. Tao, Pamela M. Bloomer, Michael A. Dunn, Andres Duarte‐Rojo   +5 more
wiley   +1 more source

Assessment of nomogram model for the prediction of esophageal variceal hemorrhage in hepatitis B-induced hepatic cirrhosis. [PDF]

Eur J Gastroenterol Hepatol
Xu J, Tan L, Jiang N, Li F, Wang J, Wang B, Li S.   +6 more
europepmc   +1 more source

Splenectomy with Portoazygous Disconnection for Correction of Systemic Hemodynamic Disorders in Hepatic Cirrhosis Patients with Portal Hypertension: A Prospective Single-Center Cohort Study. [PDF]

Can J Gastroenterol Hepatol, 2020
Zeng DB, Di L, Guo QL, Ding J, Zhao XF, Lu SC.   +5 more
europepmc   +1 more source

N6‐Methyladenosine (m6A) in Liver Disease: Pathogenic Mechanisms and Therapeutic Potential

iNew Medicine, EarlyView.
ABSTRACT Accumulating evidence highlights the critical role of epigenetic modifications, particularly N6‐methyladenosine (m6A), in liver disease. As the most abundant RNA modification in eukaryotic cells, m6A is dynamically regulated by multicomponent m6A methyltransferases (e.g., METTL3 and METTL14), demethylases (FTO and ALKBH5), and m6A‐binding ...
Yingfen Chen, Ru Ya, Ziling Zhang, Siyue Dong, Seol Hee Park, Wonhyo Seo, Yong He   +6 more
wiley   +1 more source

Hepatoprotective activity of Lactéol® forte and quercetin dihydrate against thioacetamide-induced hepatic cirrhosis in male albino rats. [PDF]

J Cell Mol Med
Saad HM, Oda SS, Alexiou A, Papadakis M, Mahmoud MH, Batiha GE, Khalifa E.   +6 more
europepmc   +1 more source

Gut microbiome‐derived metabolites show promise in cancer research and therapy

Interdisciplinary Medicine, EarlyView.
The metabolites produced by the gut microbiome, which are subject to regulation by multiple factors, play a pivotal role in the progression of various types of cancer. These metabolites not only function as potential biomarkers for the early detection and monitoring of tumor development, but also actively participate in cancer therapeutic processes ...
Kangjie Yang, Yifan Wang, Daolin Tang, Peilong Li, Lutao Du   +4 more
wiley   +1 more source

Localized pseudomembranous gastritis associated with hepatic cirrhosis and portal hypertensive gastropathy: a case report. [PDF]

J Surg Case Rep
Tran P, Sai P R, Prasad C, Parsa C.
europepmc   +1 more source

Jaundice and ? Hepatic Cirrhosis [PDF]

Proceedings of the Royal Society of Medicine, 1936
openaire   +2 more sources

A Comparative Study of Ultrasonography and CT Venography in the Diagnosis of Budd‐Chiari Syndrome

Journal of Clinical Ultrasound, EarlyView.
Budd‐Chiari syndrome (BCS) is characterized by hepatic venous outflow obstruction from the hepatic veins to the junction of the inferior vena cava (IVC) and right atrium. Ultrasound (US) and CT venography (CTV) are used as imaging techniques for the diagnosis of BCS, and We compared the diagnostic efficacy of the two modalities. The results showed that
Tiling Jiang, Mingyue Qu, Qian Zhang, Donghua Shen, Yan Liu, Baoshi Guo, Gong Wang   +6 more
wiley   +1 more source