Results 181 to 190 of about 51,855 (253)

Acute Liver Injury Following Outpatient Trimethoprim‐Sulfamethoxazole Use for Small Intestinal Bacterial Overgrowth: A Case Report

open access: yesClinical Case Reports, Volume 14, Issue 7, July 2026.
ABSTRACT Drug‐induced liver injury (DILI) is a leading cause of acute liver failure in the United States and remains difficult to predict and diagnose. Trimethoprim‐sulfamethoxazole (TMP‐SMX) is widely prescribed and generally well tolerated, yet rare cases of severe idiosyncratic hepatotoxicity have been reported.
Kaylie Duit   +3 more
wiley   +1 more source

Advanced Management of Acute Intermittent Porphyria: The Role of Givosiran Therapy in Improving Long‐Term Outcomes‐A Case Study

open access: yesClinical Case Reports, Volume 14, Issue 7, July 2026.
ABSTRACT Acute intermittent porphyria is a rare disorder causing neurotoxic precursor accumulation and severe neurological complications. We report a case progressing to tetraplegia and respiratory failure with delayed diagnosis. Treatment with hemin and givosiran resulted in prevention of attacks and functional recovery, highlighting the importance of
Natália Rebeca Alves de Araújo Karpejany   +7 more
wiley   +1 more source

S100B protein as a marker of minimal hepatic encephalopathy. [PDF]

open access: yesPrz Gastroenterol
Pisarek W   +2 more
europepmc   +1 more source

The Challenge of Determining the Etiology of Encephalopathy in an Elderly Patient

open access: yesClinical Case Reports, Volume 14, Issue 7, July 2026.
ABSTRACT Encephalopathy is a heterogeneous clinical syndrome with numerous neurological and systemic etiologies. We report the case of a 67‐year‐old man, a chronic ethanol consumer, admitted with a one‐week history of confusional syndrome. Initial laboratory tests revealed severe hypercalcemia, acute kidney injury, mild anemia, and hyperproteinemia ...
Vlad Alexandru Ionescu   +9 more
wiley   +1 more source

Methotrexate‐Induced Drug Hypersensitivity Syndrome Presenting With Acute Cerebral Infarction in End‐Stage Renal Disease: A Case Report

open access: yesClinical Case Reports, Volume 14, Issue 7, July 2026.
ABSTRACT Methotrexate (MTX) is primarily renally excreted, making patients with end‐stage renal disease (ESRD) highly vulnerable to drug accumulation and toxicity. While severe drug‐induced hypersensitivity syndrome (DIHS) is a known life‐threatening adverse reaction, its association with acute central nervous system complications, specifically ...
Le Mu   +6 more
wiley   +1 more source

Icariin Alleviates Diabetes‐Associated Cognitive Dysfunction Through Modulation of LCN2–MEK/ERK Signaling‐Associated Neuroinflammation

open access: yesCNS Neuroscience &Therapeutics, Volume 32, Issue 7, July 2026.
Icariin protects against diabetes‐associated cognitive dysfunction by effectively inhibiting the LCN2–MEK/ERK axis and alleviating neuroinflammation. These findings demonstrate that targeting this signaling pathway with icariin may offer a promising strategy for treating cognitive impairment in diabetes. ABSTRACT Objective Diabetes‐associated cognitive
Xinyi Jiao   +6 more
wiley   +1 more source

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