Results 61 to 70 of about 615,949 (181)

Cardiomyopathy: pathogenesis and therapeutic interventions

MedComm, Volume 5, Issue 11, November 2024.
Cardiomyopathy is a group of diseases characterized by structural and functional damage to the myocardium. Many specific gene mutations, environmental factors, and metabolic disorders may cause cardiomyopathy. Traditional therapeutic includes drug and surgery. With the growing comprehension of the molecular mechanisms underlying cardiomyopathy.
Shitong Huang, Jiaxin Li, Qiuying Li, Qiuyu Wang, Xianwu Zhou, Jimei Chen, Xuanhui Chen, Abdelouahab Bellou, Jian Zhuang, Liming Lei   +9 more
wiley   +1 more source

Azadirachta indica Leaf Extract Ameliorates Hyperglycemia and Hepatic Glycogenosis in Streptozotocin-induced Diabetic Wistar Rats [PDF]

, 2010
We studied the effects of ethanolic leaf extract of Azadirachta indica (AIE) on hepatic microscopic anatomy and oxidative stress markers in diabetic rats.
Oluwole B. Akinola, Laura Zatta, Olufunke O. Dosumu, Oluwafunmike S. Akinola, Ezekiel A. Caxton-Martins, Luciana Dini   +5 more
core   +1 more source

Azadirachta indica Leaf Extract Ameliorates Hyperglycemia and Hepatic Glycogenosis in Streptozotocin-induced Diabetic Wistar Rats [PDF]

, 2011
We studied the effects of ethanolic leaf extract of Azadirachta indica (AIE) on hepatic microscopic anatomy and oxidative stress markers in diabetic rats.
Dosumu, Olufunke O.; Anatomy Department, College of Medicine, University of Lagos, Nigeria, Dini, Luciana; Department of Comparative Anatomy & Cytology, Faculty of Biological and Environmental Sciences and Technology, University of Salento, 73100 Lecce, Italy., Akinola, Oluwafunmike S.; Department of Anatomy, Faculty of Basic Medical Sciences, College of Health Sciences, University of Ilorin, Ilorin 240003, Nigeria., Caxton-Martins, Ezekiel A.; Department of Anatomy, Faculty of Basic Medical Sciences, College of Health Sciences, University of Ilorin, Ilorin 240003, Nigeria., Zatta, Laura; Department of Comparative Anatomy & Cytology, Faculty of Biological and Environmental Sciences and Technology, University of Salento, 73100 Lecce, Italy., Akinola, Oluwole B.; Department of Anatomy, Faculty of Basic Medical Sciences, College of Health Sciences, University of Ilorin, Ilorin 240003, Nigeria.   +5 more
core   +1 more source

A new variant form of hepatic glycogenosis with acid maltase deficiency [PDF]

Japanese journal of human genetics, 1984
A 6-year-old Japanese girl with acid maltase deficiency showed unusual clinical features of the disease; doll-like face, short stature, hepatomegaly, proximal renal tubular acidosis, but no muscular weakness or hypotonia. Diagnosis of acid maltase deficiency was made based on the following findings of the liver tissue obtained by surgical biopsy ...
N, Ninomiya, T, Terashima, T, Iwamasa, I, Matsuda   +3 more
openaire   +2 more sources

Long‐term personalized high‐protein, high‐fat diet in pediatric patients with glycogen storage disease type IIIa: Evaluation of myopathy, metabolic control, physical activity, growth, and dietary compliance

Journal of Inherited Metabolic Disease, Volume 47, Issue 5, Page 1001-1017, September 2024.
Abstract Dietary lipid manipulation has recently been proposed for managing glycogen storage disease (GSD) type IIIa. This study aimed to evaluate the myopathic, cardiac, and metabolic status, physical activity, growth, and dietary compliance of a personalized diet high in protein and fat for 24 months.
Sema Kalkan Uçar, Yasemin Atik Altınok, Yelda Mansuroglu, Ebru Canda, Havva Yazıcı, Merve Yoldaş Çelik, Fehime Erdem, Ayşe Yüksel Yanbolu, Zülal Ülger, Mahmut Çoker   +9 more
wiley   +1 more source

Mutational spectrum and genotype–phenotype correlation in Mexican patients with infantile‐onset and late‐onset Pompe disease

Molecular Genetics &Genomic Medicine, Volume 12, Issue 7, July 2024.
Mutational spectrum and genotype–phenotype correlation in a large case series of Pompe disease in Mexico with identification of two novel gene variants not reported previously. Abstract Background Pompe Disease (PD) is a metabolic myopathy caused by variants in the GAA gene, resulting in deficient enzymatic activity.
Valentina Martinez‐Montoya, Luz María Sánchez‐Sánchez, Roberto Sandoval‐Pacheco, Diana Mónica Anaya Castro, Carmen Araceli Arellano‐Valdez, Carmen Amor Ávila‐Rejón, Pedro Alejandro Aguilar‐Juárez, Martín Espino‐Pluma, Cruz Antonio González‐Santillanes, Rosa Isela Martínez‐Segovia, Dorian Olmos‐Morfin, Ofelia Padilla‐De la Torre, Ishar Solís‐Sánchez, Mónica Vázquez‐Del Mercado Espinosa, Camilo Ernesto Villarroel‐Cortés, Jesús Salvador Velarde‐Félix, Jaime López‐Valdez, Julio Olaiz‐Urbina, Edgar Ricárdez‐Marcial, Imelda Vergara‐Sánchez, Pablo Radillo‐Díaz, Ekaterina Kazakova, Beatriz De la Fuente‐Cortez, Luz del Carmen Marquez‐Quiróz, Benjamín Torres‐Octavo, Rubicel Diaz‐Martinez   +25 more
wiley   +1 more source

Multigenerational study of the hepatic effects exerted by the consumption of nonylphenol- and 4-octylphenol-contaminated drinking water in Sprague-Dawley rats [PDF]

, 2007
Our multigenerational study evaluates the hepatic effects of the xenoestrogens nonylphenol (NP), and 4-octylphenol (4OP) on male and female rats when they are exposed uninterruptedly, from conception to adult age, to tap water containing 25 ppm of NP or ...
Monterde, J. G., Luzardo, O. P., Blanco, A., Boada, L. D., Hernández-Rodríguez, G., Zumbado, M.   +5 more
core   +1 more source

Histological characterization of liver involvement in systemic mastocytosis

Liver International, Volume 44, Issue 7, Page 1680-1688, July 2024.
Abstract Background and Aims Systemic mastocytosis (SM) is characterized by the accumulation of atypical mast cells (MCs) in organs. Liver histology of SM has been marginally described and accurate histological classification is critical, given the consequences of aggressive SM diagnosis.
Julien Rossignol, Danielle Canioni, Achille Aouba, Cristina Bulai‐Livideanu, Stéphane Barete, Charles Lancesseur, Laura Polivka, Marine Madrange, Thomas Ballul, Antoine Neuraz, Celine Greco, Julie Agopian, Fabienne Brenet, Patrice Dubreuil, Richard Lemal, Olivier Tournilhac, Louis Terriou, David Launay, Laurence Bouillet, Clément Gourguechon, Laurent Frenzel, Cécile Meni, Caroline Gaudy‐Marqueste, Marie Gousseff, Edwige Le Mouel, Mohamed Hamidou, Antoine Neel, Dana Ranta, Roland Jaussaud, Philippe Guilpain, Thierry J Molina, Julie Bruneau, Ludovic Lhermitte, Nicolas Garcelon, Rose‐Marie Javier, Fabien Pelletier, Florence Castelain, Frederique Retornaz, Quentin Cabrera, Patricia Zunic, Marie Pierre Gourin, Ewa Wierzbicka‐Hainaut, Jean François Viallard, Christian Lavigne, Cyrille Hoarau, Isabelle Durieu, Maël Heiblig, Sophie Dimicoli‐Salazar, Jose M Torregrosa‐Diaz, Angèle Soria, Michel Arock, Olivier Lortholary, Christine Bodemer, Stanislas Pol, Vincent Mallet, Olivier Hermine, Ghandi Damaj, on behalf the CEREMAST Network   +57 more
wiley   +1 more source

[Surgical therapy of metabolic liver diseases (glycogenosis, hypercholesterolemia)]. [PDF]

, 1998
Up-to-date, most patients with serious chronic hepatic disease are best treated by liver transplantation. It has been confirmed the striking benefit of liver transplantation also for patients with glycogen storage disease or homozygous familial ...
E. Forni, H. Bismuth, MERIGGI, FRANCESCO
core  

Relationship between genetic variation at PPP1R3B and levels of liver glycogen and triglyceride [PDF]

, 2018
Genetic variation at rs4240624 on chromosome 8 is associated with an attenuated signal on hepatic computerized tomography, which has been attributed to changes in hepatic fat.
Hobbs, Helen H, Len A. Pennacchio, Lauridsen, Bo K., Cohen, Jonathan C., Stender, Stefan, Diane E. Dickel, Cohen, Jonathan C, Smagris, Eriks, Pennacchio, Len A., Lauridsen, Bo K, Dickel, Diane E., Børge G. Nordestgaard, Tybjærg-Hansen, Anne, Kofoed, Klaus F., Hobbs, Helen H., Helen H. Hobbs, Kofoed, Klaus F, Bo K. Lauridsen, Stefan Stender, Nordestgaard, Børge G., Jonathan C. Cohen, Pennacchio, Len A, Klaus F. Kofoed, Anne Tybjærg‐Hansen, Tybjærg‐Hansen, Anne, Nordestgaard, Børge G, Dickel, Diane E, Eriks Smagris   +27 more
core   +1 more source