Results 61 to 70 of about 51,489 (260)

Hepatic Veins Belong to “the Veins of the Digestive Tube” in the Dog

Japanese Journal of Pharmacology, 1988
Pharmacological responsiveness of isolated strips of the canine hepatic veins was investigated. Circular strips showed a low responsiveness to 5-hydroxytryptamine, a low sensitivity to norepinephrine and a high sensitivity to histamine. Longitudinal strips developed greater tensions to norepinephrine than circular strips.
openaire   +2 more sources

Targeting PLD3 Reverses the Immunosuppressive Niche by Reprogramming Tumor‐Associated Macrophages and Potentiates Antitumor Immunity

Advanced Science, EarlyView.
PLD3 activates the lysosomal‐AKT‐NF‐κB axis to drive cellular senescence in macrophages, establishing an immunosuppressive TME by limiting the infiltration of cytotoxic T, NK, and NKT cells, which confers resistance to anti‐PD‐1 therapy. Abrine inhibits PLD3 expression, restoring antitumor immunity and synergizing with anti‐PD‐1 treatment.
Xingtu Qin, Qiong Li, Xuemei Xu, Yuhan Wu, Yin Zhu, Jieqiong Wu, Yuan Fang, Qiubei Chen, Shuyang Wang, Jiang Yu, Yaping Ye, Hongli Jiao   +11 more
wiley   +1 more source

Multi‐Axis Stretchable Zippers for Personalized Wound Healing

Advanced Science, EarlyView.
Multi‐axis stretchable zippers can adapt to complex wound morphologies and enable personalized wound treatment through programmable contraction. This morphological matching strategy helps accelerate wound closure, improve blood perfusion, promote epithelial regeneration, and enhance collagen remodeling, pioneering new directions for personalized and ...
Siyuan Cai, Guang Yao, Zijian Chen, Shiqi Zhou, Peisi Li, Liheng Lin, Huake Yang, Ziyi Zhou, Linbo Jin, Xingyi Gan, Chenzheng Zhou, Zhen Cai, Taisong Pan, Min Gao, Dongli Fan, Yuan Lin, Yiming Zhang   +16 more
wiley   +1 more source

SuFEx‐Enabled Reprogramming of Flavonoids for Selective α‐Glucosidase Covalent Inhibition

Advanced Science, EarlyView.
Selective inhibition of intestinal α‐glucosidase remains limited by poor enzyme specificity and off‐target metabolic effects. Here, SuFEx click chemistry is used to reprogram natural flavonoids into covalent inhibitors with enhanced α‐glucosidase selectivity and controlled reactivity. This strategy enables effective regulation of carbohydrate digestion
Fengyu Guo, Liwei Zhang, Minlong Wang, Yanjin Du, Tianyu Zhang, Hao Chen, Jiazeng Sun, Yang Yu, Zude He, Jie An, Xiaoxu Zhang, Weilin Lin, Fazheng Ren, Pengjie Wang, Ping Liu   +14 more
wiley   +1 more source

Congenital Arterioportal Fistula of the Liver: Report of a Case

Siriraj Medical Journal, 2015
Congenital intrahepatic shunts are uncommon anomalies consisting of abnormal connections between the hepatic arteries, portal veins, hepatic veins or systemic venous system. It can be found incidentally or in symptomatic infants.
Preeyacha Pacharn
doaj  

Left trisectionectomy combined with resection of the right hepatic vein and inferior vena cava after right hepatic vein embolization for advanced intrahepatic cholangiocarcinoma

Surgical Case Reports, 2019
Background When the inferior right hepatic vein (IRHV) is present, left hepatic trisectionectomy with resection of the right hepatic vein (RHV) is theoretically possible without reconstruction of the RHV. We here report a successful case of this extended
Toshihiro Suzuki, Tomoki Ebata, Yukihiro Yokoyama, Takashi Mizuno, Tsuyoshi Igami, Junpei Yamaguchi, Shunsuke Onoe, Nobuyuki Watanabe, Masato Nagino   +8 more
doaj   +1 more source

NIR‐II‐Trackable LYTACs Phyto‐Nanotheranostics for Source‐Microenvironment Dual‐Track ROS Regulation in Acute Gouty Arthritis

Advanced Science, EarlyView.
The TPR‐LYTACs nanomaterial offers a dual‐pathway strategy for precise gouty arthritis treatment by targeting and degrading the ROS‐producing enzyme NOX2 inside macrophages while its antioxidant core clears accumulated ROS outside. This “source inhibition and microenvironment scavenging” approach, guided by NIR‐II imaging, effectively controls local ...
Jian Zhang, Yingying Wang, Lujie Yu, Chunmei Jiang, Haoyu Liu, Yaohua Chen, Shutong Wu, Qin Liu, Lingling Wei, Xiaochun Zheng, Huifang Hao, Mengting Gao, Weiwei Kang, Rong Dai, Ziliang Zheng, Ruiping Zhang   +15 more
wiley   +1 more source

Characterization of the Normal Portal and Hepatic Blood Flow of Adult Holstein-Friesian Cows

Animals, 2019
In the past, hepatic blood flow in cows was invasively characterized to investigate different pathologies and physiological conditions. However, hepatic blood flow can be easily evaluated with transabdominal Doppler ultrasound.
J. Daniel Barreiro-Vázquez, Marta Miranda, M. Isabel Barreiro-Vilanova, F. Javier Diéguez, Andrés Barreiro-Lois   +4 more
doaj   +1 more source

The key role of the hepatic veins collaterals in the modern liver surgery. [PDF]

Hepatobiliary Surg Nutr, 2023
Panaro F, Guiu B, Herrero A.
europepmc   +1 more source

NMI Regulates Adipose Adaptive Thermogenesis Through TLR4/IRF3 Signaling to Promote Obesity

Advanced Science, EarlyView.
Adipose tissue‐derived NMI is secreted under metabolic stress and suppresses adaptive thermogenesis through TLR4/IRF3 signaling, repressing the PPARα/PGC‐1α/UCP1 thermogenic transcriptional program. Genetic ablation or anti ‐ NMI monoclonal antibody treatment enhances energy expenditure, protects against DIO, and ameliorates adipose tissue inflammation,
Ting‐Ting Li, Xin‐Yuan Zhao, Min Zhang, Zhuang‐Feng Weng, Xiao‐Ran Guo, Ying‐Fang Liu, Qiao‐Ping Wang, Huan‐Huan Liang   +7 more
wiley   +1 more source