Results 31 to 40 of about 2,649 (174)

Contribution of endosomal proteins EHD1 and EHD4 to the HIV‐1 replication cycle

The FEBS Journal, EarlyView.
EHD1 and EHD4, two key trafficking proteins, regulate multiple stages of HIV‐1 infection: In producer cells, they help produce fully infectious virus particles, regulate Envelope protein incorporation in a cell‐type‐dependent manner, and limit the accumulation of antiviral IFITM proteins in virions.
Grégory Pacini, Konstantinos Poalas, Margaux Versapuech, Clarisse Berlioz‐Torrent, Katy Janvier   +4 more
wiley   +1 more source

Psychosocial vulnerabilities and loss to follow‐up in people living with HIV in France

HIV Medicine, EarlyView.
Abstract Background Migration status is consistently associated with a higher risk of loss to follow‐up (LTFU). We investigated how sex, sexual orientation and social vulnerabilities affect the association between migration status and LTFU for hospital care in people living with HIV, using data from the ANRS CO9‐COPANA cohort linked to the nationwide ...
Charlène Mafuta, Sophie Grabar, Laurence Lievre, Cécile Goujard, Jean‐Paul Viard, Olivier Bouchaud, Laurence Meyer, Rémonie Seng, Sophie Abgrall   +8 more
wiley   +1 more source

INTERMEDIATE ENDEMICITY OF HEPATITIS A VIRUS INFECTION IN RURAL SETTLEMENT PROJECTS OF SOUTHWEST GOIÁS, BRAZIL

Arquivos de Gastroenterologia, 2015
BackgroundRural populations present an elevated risk of exposure to hepatitis A virus.ObjectiveThe objective of this study was to estimate the prevalence and risk factors associated with hepatitis A virus infection among residents of rural settlement ...
Raquel Silva PINHEIRO, Lyriane Apolinário de ARAÚJO, Karlla Antonieta Amorim CAETANO, Marcos André de MATOS, Megmar Aparecida dos Santos CARNEIRO, Sheila Araújo TELES   +5 more
doaj   +1 more source

Hepatitis B virus infection with high HBsAg and undetectable DNA levels in untreated blood donors: Viral mechanisms and transfusion safety implications

Transfusion, EarlyView.
Abstract Background Blood donor screening occasionally identifies individuals with high HBV surface antigen (HBsAg) levels despite undetectable or extremely low HBV DNA. Molecular basis and transfusion risk of this discordant profile remain unclear. Study Design and Methods Seventy‐five blood donors with HBsAg >100 IU/mL and undetectable or very low ...
Maelenn Païline Delcourt, Marion Vermeulen, Aneta Kopacz, Manuela Miletic, Andrew Saville, Christoph Niederhauser, Jean‐Michel Pawlotsky, Syria Laperche, Daniel Candotti   +8 more
wiley   +1 more source

Infecção pelo vírus da hepatite A em área indígena da Amazônia oriental brasileira

Revista da Sociedade Brasileira de Medicina Tropical, 2004
A hepatite viral A representa importante problema de saúde pública em todo o mundo, estando relacionada às condições sócioeconômicas e de higiene da população.
Heloisa Marceliano Nunes, Manoel do Carmo Pereira Soares, Helena Maria Ribeiro Silva   +2 more
doaj   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, Volume 16, Issue 7, Page 1271-1292, July 2026.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Investigating the role of a conserved hydrophobic pocket of gp41 in the anti‐HIV activity of fusion inhibitors

Protein Science, Volume 35, Issue 6, June 2026.
Abstract Membrane fusion between HIV and host cells requires interaction between the N‐terminal and C‐terminal repeat regions (NHR and CHR) of the gp41 envelope subunit. A deep hydrophobic pocket (HP) on the surface of NHR is considered crucial in this interaction.
Daniel Polo‐Megías, Mario Cano‐Muñoz, Laura Sánchez‐Martínez, Sara Lestani, Christiane Moog, Thomas Decoville, María Carmen Salinas‐García, José Antonio Gavira, Ana Cámara‐Artigas, Francisco Conejero‐Lara   +9 more
wiley   +1 more source

External Evaluation of Population Pharmacokinetic Models of Cabotegravir, During Its Oral and Intramuscular Administration in HIV‐Infected Patients

CPT: Pharmacometrics &Systems Pharmacology, Volume 15, Issue 6, June 2026.
ABSTRACT Cabotegravir (CAB), combined with rilpivirine, is the first long‐acting injectable therapy approved for HIV‐1 maintenance treatment. While adherence and patient satisfaction have been improved, pharmacokinetic (PK) variability remains a concern.
Quentin Renou, Nadège Néant, Alexandre Destere, Jennifer Lagoutte‐Renosi, Matthieu Grégoire, François Parant, Sébastien Lalanne, Florian Lemaitre, Peggy Gandia, Nicolas Venisse, Stéphane Bouchet, Minh P. Lê, Patrice Muret, Gilles Peytavin, Caroline Solas, Sihem Benaboud, the CARLA Study Group, Benoît Bailly, Vincent Gendrin, Timothhee Klopenstein, Souheil Zayet, Quentin Lepiller, Fabienne Bozon, Anne‐Sophie Brunel, Bruno Hoen, Laurent Hustache‐Mathieu, Camille Tumiotto, Mojgane Hemssamfar, Fabrice Bonnet, Ali Si‐Mohammed, Lionel Piroth, Marielle Buisson, Sophie Mahy, Michel Duong, Vinca Icard, Mary‐Anne Trabaud, Dulce Alfaiate, Agathe Becker, Evelyne Braun, Florence Brunel, Matthieu Godinot, Thomas Perpoint, Clément Javaux, Céline Boschi, Philippe Colson, Anne Motte, Véronique Obry‐Roguet, Sylvie Brégigeon, Olivia Faucher‐Zaegel, Hélène Laroche, Maeva Dos Santos, Isabelle Ravaux, Catherine Dhiver, Christelle Tomei, Amélie Ménard, Matthieu Million, Patrick Philibert, Christina Psomas, Jakub Kowalczyk, Simona‐Loredana Berbescu, Catherine Michel, Elisabeth André‐Garnier, Thomas Drumel, Clotilde Allavena, Eric Billaud, Sabelline Bouchez, Cécile Brunet‐Cartier, Colin Deschanvres, François Raffi, Véronique Reliquet, Gwennaelle Querne, Cecile Mear‐Passard, Antoine Asquier, Charlotte Moyon, Virginie Beslon, Lio Collias, Anne‐Geneviève Marcelin, Vincent Calvez, Diane Descamps, Valentine Ferré, Yazdanpanah Yazdan, Jade Ghosn, Valérie Pourcher, Marc‐Antoine Valantin, Gwenaël Le Moal, David Plainchamp, Anne Maillard, François Benezit, Cédric Arvieux, Pierre Gantner, Christine Cheneau, Axel Ursenbach, Baptiste Hoellinger, Céline Melounou, David Rey, Yves Hansmann   +95 more
wiley   +1 more source

Prevalência da infecção pelos vírus das hepatites A e E em escolares de município da Amazônia Matogrossense

Revista da Sociedade Brasileira de Medicina Tropical, 2002
Avaliou-se a prevalência de anticorpos para as hepatites A e E em 487 crianças de 2 a 9 anos, de um município da Amazônia matogrossense. As prevalências de anti-VHA e anti-VHE foram 86,4% (IC95% 83 -- 89,3) e 4,5% (IC95% 2,9 -- 6,9) respectivamente.
Assis Sandra Breder, Souto Francisco José Dutra, Fontes Cor Jesus Fernandes, Gaspar Ana Maria Coimbra   +3 more
doaj  

Cancer risks and trends between 1997 and 2018, and effects of restored immunity in people living with HIV: Results from the ANRS CO4 French hospital database on HIV

International Journal of Cancer, Volume 158, Issue 9, Page 2298-2308, 1 May 2026.
What's new? This large nation‐wide cohort study provides a comprehensive 20‐year analysis of cancer trends among people living with HIV in France, highlighting persistent excess risks for virus‐related cancers despite effective antiretroviral therapy and immune restoration.
Sophie Grabar, Paula Lakrout, Valérie Potard, Aurélien Belot, Jacques Cadranel, Christine Jacomet, Christine Katlama, Esaïe Marshall, Olivier Lambotte, Romain Palich, Sylvie Ronot‐Bregigeon, Jean‐Philippe Spano, Anne‐Marie Bouvier, Alain Makinson, Dominique Costagliola   +14 more
wiley   +1 more source