Results 31 to 40 of about 112,075 (306)

Alcoholic Liver Disease in the Asian–Pacific Region with High Prevalence of Chronic Viral Hepatitis

Journal of Medical Ultrasound, 2016
The hospitalized cases and mortality from alcoholic liver disease (ALD) are increasing in Taiwan and worldwide. Meanwhile, the Asia–Pacific region also has a high prevalence of hepatitis B virus (HBV) and hepatocellular carcinoma (HCC).
Sien-Sing Yang
doaj   +1 more source

Intestinal fungi contribute to development of alcoholic liver disease [PDF]

, 2017
This study was supported in part by NIH grants R01 AA020703, U01 AA021856 and by Award Number I01BX002213 from the Biomedical Laboratory Research & Development Service of the VA Office of Research and Development (to B.S.). K.H.
Ali Keshavarzian, An-Ming Yang, Bernd Schnabl, Bode, Chien-Sheng Chen, Claus Hellerbrand, Cristina Llorente, Derrick E. Fouts, Ece A. Mutlu, Fettweis, Fouts, Gordon D. Brown, Guadalupe Garcia-Tsao, Hal M. Hoffman, Jun Xu, Karen Beeri, Katrin Hochrath, Kelvin Moncera, Kim Freese, Lee, Lirui Wang, Liu, Manolito G. Torralba, Peng Chen, Peter Stärkel, Phillipp Hartmann, Ramon Bataller, Samuel B. Ho, Sena Bluemel, Serene M.L. Lee, Sokol, Tatiana Kisseleva, Tatsuo Inamine, Wagner, Wajahat Z. Mehal, Yamahiro, Yang, Yukinori Koyama   +37 more
core   +3 more sources

Functional Microbiomics Reveals Alterations of the Gut Microbiome and Host Co‐Metabolism in Patients With Alcoholic Hepatitis

Hepatology Communications, 2020
Alcohol‐related liver disease is a major public health burden, and the gut microbiota is an important contributor to disease pathogenesis. The aim of the present study is to characterize functional alterations of the gut microbiota and test their ...
Bei Gao, Yi Duan, Sonja Lang, Dinesh Barupal, Tsung‐Chin Wu, Luis Valdiviez, Bryan Roberts, Ying Yng Choy, Tong Shen, Gregory Byram, Ying Zhang, Sili Fan, Benjamin Wancewicz, Yan Shao, Kevin Vervier, Yanhan Wang, Rongrong Zhou, Lu Jiang, Shilpa Nath, Rohit Loomba, Juan G. Abraldes, Ramon Bataller, Xin M. Tu, Peter Stärkel, Trevor D. Lawley, Oliver Fiehn, Bernd Schnabl   +26 more
doaj   +1 more source

Veillonella Bacteremia in Alcoholic Hepatitis

Case Reports in Hepatology, 2021
Veillonella species are commensal bacteria of the human oral, gut, and vaginal microbiota that are rarely identified as clinically relevant pathogens.
Patrick Lee, Brandon K. K. Fields, Tom Liang, Michael P. Dubé, Seth Politano   +4 more
doaj   +1 more source

Immunotherapy in hepatocellular carcinoma: the complex interface between inflammation, fibrosis, and the immune response. [PDF]

, 2019
Hepatocellular carcinoma (HCC) is the third leading cause of cancer deaths worldwide and confers a poor prognosis. Beyond standard systemic therapy with multikinase inhibitors, recent studies demonstrate the potential for robust and durable responses ...
Fong, Lawrence, Keenan, Bridget P, Kelley, Robin K   +2 more
core   +2 more sources

Alcoholic Hepatitis: A Review [PDF]

Alcohol and Alcoholism, 2019
AbstractAlcoholic liver disease (ALD) represents a spectrum of injury, ranging from simple steatosis to alcoholic hepatitis to cirrhosis. Regular alcohol use results in fatty changes in the liver which can develop into inflammation, fibrosis and ultimately cirrhosis with continued, excessive drinking.
Nooshin, Hosseini, Julia, Shor, Gyongyi, Szabo   +2 more
openaire   +2 more sources

Infections in Alcoholic Hepatitis

Journal of Clinical and Translational Hepatology, 2022
Severe alcoholic hepatitis (sAH) is defined by a modified discriminant function ≥32 or model for end-stage liver disease (MELD) >20. Patients with sAH are in an immunocompromised state attributed to cirrhosis-related immunoparesis and corticosteroid use.
Bhupinder Kaur, Russell Rosenblatt, Vinay Sundaram   +2 more
openaire   +2 more sources

NAFLD‐related hepatocellular carcinoma: The growing challenge

Hepatology, EarlyView., 2022
Risk and protective factors for NAFLD‐related hepatocellular carcinoma Abstract Hepatocellular carcinoma (HCC) is a common cause of cancer‐related mortality and morbidity worldwide. With the obesity pandemic, NAFLD‐related HCC is contributing to the burden of disease exponentially.
Pir Ahmad Shah, Rashmee Patil, Stephen A. Harrison   +2 more
wiley   +1 more source

Comparison of TNF-α Levels in Alcoholic Liver Disease Patients with and without Hepatitis: A Cross-sectional Study in Coastal Karnataka, India [PDF]

National Journal of Laboratory Medicine
Introduction: Alcohol-induced liver injury triggers inflammatory reactions through pro-inflammatory cytokine Tumour Necrosis Factor-α (TNF-α). The estimation of TNF-α would provide valuable information on the degree of activation of immune system and ...
TM Anuraghi, Krishnamoorthy Srilatatha, Jinsha Fathima, Yassir Shaheena   +3 more
doaj   +1 more source

Toll-like receptor-mediated signaling cascade as a regulator of the inflammation network during alcoholic liver disease [PDF]

, 2014
Chronic abuse of alcohol leads to various histological abnormalities in the liver. These are conditions collectively known as alcoholic liver disease (ALD). Currently, ALD is considered to be one of the major causes of death worldwide.
Alisi, A., Ceccarelli, S, Nobili, V
core   +1 more source