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Viral hepatitis in subhuman primates and its relationship to human viral hepatitis
Virchows Archiv Abteilung A Pathologische Anatomie, 1969Viral hepatitis can occur spontaneously in chimpanzees and patas monkeys, usually producing only mild clinical symptoms which are difficult, if not impossible, to recognize without adequate laboratory studies or liver biopsy. The disease, however, can be transferred to other subhuman primates as well as to human beings by contact.
H F, Smetana, A D, Felsenfeld
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Viral hepatitis: Human genes that limit infection
Best Practice & Research Clinical Gastroenterology, 2010Treatment response and susceptibility to chronic viral hepatitis C and B may be modified by host genetic factors. The majority of genetic variants that confer a significant risk have been localized in genes involved in immune response. However, many findings could not be replicated and almost none of the identified risk factors had a noticeable impact ...
Frank, Grünhage, Jacob, Nattermann
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Viral Hepatitis Associated with Sub‐human Primates*
Transfusion, 1963Recent epidemiologic evidence has accumulated indicating that certain chimpanzees and other primates act as carriers of human hepatitis virus. Outbreaks of human hepatitis in which primates have been so implicated are summarized in this paper, and the significant epidemiologic findings are emphasized.
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Human leukocyte antigen phenotypes and hepatitis C viral load
Journal of Clinical Virology, 2005After hepatitis C virus (HCV) infection, 55% to 85% of patients become chronic carriers. HCV-RNA could be detected in the sera of these patients though the viral load varies. Various factors may be involved in determining the viral load.In this study, we want to investigate the relationship between human leukocyte antigen phenotypes and hepatitis C ...
Li-Yu, Wang +6 more
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Glucose Tolerance and Metabolic Changes in Human Viral Hepatitis
Clinical Science, 19731. Glucose tolerance and metabolic changes after intravenous glucose were studied in fifteen patients with acute viral hepatitis and in eight patients after recovery. In the acute stage glucose tolerance was significantly impaired compared with control subjects or with patients after recovery from hepatitis. 2.
C O, Record +3 more
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Primates as a Model for Human Viral Hepatitis: Transmission of Infection by Human Hepatitis B Virus
Vox Sanguinis, 1973Abstract. With complement fixation, Australia antigen was detected in one, and antibody in 6 out of 50 chimpanzees. Seven other apes, and 48 monkeys were negative. All positive chimpanzees clustered in one colony comprising 15 animals, and antibody titres decreased simultaneously over a period of several months.
J, Desmyter +3 more
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Viral kinetics in hepatitis C or hepatitis C/human immunodeficiency virus-infected patients
Gastroenterology, 2005Kinetic modeling of hepatitis C virus (HCV) response to interferon (IFN)-based therapy provides insights into factors associated with treatment outcomes. HCV/human immunodeficiency virus (HIV)-co-infected patients show lower response rates vs. HCV-monoinfected patients. Reasons for this remain unclear.
Kenneth E, Sherman +6 more
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