Results 201 to 210 of about 1,307,826 (359)

Macrophage‐derived MLKL in alcohol‐associated liver disease: Regulation of phagocytosis

Hepatology, EarlyView., 2022
EtOH causes leaky gut allowing bacteria and PAMPs into the liver, resulting in hepatic inflammation and injury. We demonstrate that LPS induces STAT1‐mediated expression and phosphorylation of MLKL in macrophages and identify a novel function that myeloid MLKL translocates to phagosomes and lysosomes and regulates phagocytosis, which contributes to the
Xiaoqin Wu, Xiude Fan, Megan R. McMullen, Tatsunori Miyata, Adam Kim, Vai Pathak, Jianguo Wu, Le Z. Day, Josiah E. Hardesty, Nicole Welch, Jaividhya Dasarathy, Daniela S. Allende, Arthur J. McCullough, Jon M. Jacobs, Daniel M. Rotroff, Srinivasan Dasarathy, Laura E. Nagy   +16 more
wiley   +1 more source

Response to Comments on 'Hepatitis B Virus (HBV) Treatment Eligibility in the UK: Retrospective Longitudinal Cohort Data to Explore the Impact of Changes in Clinical Guidelines'. [PDF]

J Viral Hepat
Campbell C, Wang T, Barnes E, Matthews PC, UK Health Informatics Collaborative for Viral Hepatitis and Liver Disease.   +4 more
europepmc   +1 more source

Circulating TREM2 as a noninvasive diagnostic biomarker for NASH in patients with elevated liver stiffness

Hepatology, EarlyView., 2022
Abstract Background and Aims Reliable noninvasive biomarkers are an unmet clinical need for the diagnosis of NASH. This study investigates the diagnostic accuracy of the circulating triggering receptor expressed on myeloid cells 2 (plasma TREM2) as a biomarker for NASH in patients with NAFLD and elevated liver stiffness.
Vineesh Indira Chandran, Charlotte Wilhelmina Wernberg, Mette Munk Lauridsen, Maria Kløjgaard Skytthe, Sofie Marchsteiner Bendixen, Frederik Tibert Larsen, Camilla Dalby Hansen, Lea Ladegaard Grønkjær, Majken Storm Siersbæk, Tina Di Caterino, Sönke Detlefsen, Holger Jon Møller, Lars Grøntved, Kim Ravnskjaer, Søren Kragh Moestrup, Maja Sofie Thiele, Aleksander Krag, Jonas Heilskov Graversen   +17 more
wiley   +1 more source

PEP-Hep: A cluster randomised controlled trial of a prison education programme to improve hepatitis B and C testing uptake and treatment initiation in Ghana - A study protocol. [PDF]

BMJ Open
Senoo-Dogbey VE, Dzansi G, Akpagloh MC, Wuaku DA, Owusu Darkwa I, Boadu AA, Michael DA, Dzantor EK, Anatsui PJ.   +8 more
europepmc   +1 more source

Basiliximab in the Prophylaxis of aGVHD for Unrelated Donor Hematopoietic Stem Cell Transplantation in Patients With Thalassemia Major: A Prospective, Multicenter, Open‐Label, Randomized Controlled Study

American Journal of Hematology, EarlyView.
Zhenbin Wei, Rongrong Liu, Lingling Shi, Qiaochuan Li, Lianjin Liu, Baoshi Zheng, Chunjie Qin, Hong Chen, Guyun Wang, Meiqing Wu, Gaohui Yang, Ruolin Li, Zhaoping Gan, Qi Zhou, Jing Fan, Xuemei Zhou, Yinghua Chen, Zhiyu Zeng, Zhongming Zhang, Yongrong Lai   +19 more
wiley   +1 more source

Fatty liver disease is not associated with increased mortality in the elderly: A prospective cohort study

Hepatology, EarlyView., 2022
Graphical abstract summarizing the study design, main results and key findings Abstract Background and Aims Fatty liver disease (FLD) has been associated with excess mortality. Screening for hepatic steatosis (HS) in patients with metabolic dysfunction is therefore recommended by several guidelines, despite a paucity of evidence on the clinical ...
Laurens A. van Kleef, Milan J. Sonneveld, Maryam Kavousi, M. Arfan Ikram, Robert A. de Man, Robert J. de Knegt   +5 more
wiley   +1 more source

Editorial: World Hepatitis Day 2024: advancing hepatitis elimination, public health strategies and innovations. [PDF]

Front Public Health
Panduro A, Roman S.
europepmc   +1 more source

Recommendations from primary care physicians, family, friends and work colleagues influence patients' decisions related to hepatitis screening, medical examinations and antiviral treatment

, 2020
Michiaki Okada, Satoshi Oeda, Naoko E Katsuki, Shinji Iwane, Yasunori Kawaguchi, Saori Kawamoto, Yoshimi Tomine, Jun Fukuyoshi, Keishiro Maeyama, Hideo Tanaka, Keizo Anzai, Yuichiro Eguchi   +11 more
openalex   +2 more sources

Interferon-α2b therapy reduces liver fibrosis in chronic non-A, non-B hepatitis: A quantitative histological evaluation [PDF]

, 1993
Noboru MANABE, Michèle Chevallier, P. Chossegros, Xavier Causse, Sylviane Guérret, C. Trépo, Jean‐Alexis Grimaud   +6 more
openalex   +1 more source

Surfactant‐Enhanced Electrospun Nanofiber Filters for Efficient Viral and Bacterial Inactivation

Journal of Applied Polymer Science, EarlyView.
In this work, electrospun polyacrylonitrile (PAN) nanofibrous filters functionalized with surfactants (CTAB, CPC, and SDS) were developed for air filtration applications. The PAN nanofiber mats enable efficient particulate matter capture while simultaneously providing antimicrobial and antiviral activity against bacteria (E. coli and S.
Edilton N. da Silva, Paulo A. M. Chagas, Gustavo C. da Mata, Felipe A. Lima, Fabiana B. Furtado, Wanderley P. de Oliveira, Rejane M. T. Grotto, Clovis W. O. de Souza, Mônica L. Aguiar, Vádila G. Guerra   +9 more
wiley   +1 more source