Results 211 to 220 of about 26,125,065 (382)

Genome‐Wide Aggregated Trans Effects Analysis Identifies Genes Encoding Immune Checkpoints as Core Genes for Rheumatoid Arthritis

open access: yesArthritis &Rheumatology, EarlyView.
Objective The sparse effector “omnigenic” hypothesis postulates that the polygenic effects of common single nucleotide polymorphisms (SNPs) on a typical complex trait are mediated by trans effects that coalesce on expression of a relatively sparse set of core genes.
Athina Spiliopoulou   +9 more
wiley   +1 more source

Clinical and laboratory profile and outcomes of hospitalized COVID‐19 patients with type 2 diabetes mellitus in Ghana – A single‐center study

open access: yesEndocrinology, Diabetes &Metabolism, Volume 6, Issue 1, January 2023., 2023
This study describes the clinical and laboratory profile and outcomes of hospitalized COVID‐19 patients with type 2 diabetes mellitus (DM) in Ghana. Out of 175 patients (mean age 55.9+/−18.3 years) 64 (36.6%) had DM. Compared to non‐diabetics, DM patients were older (61.1? 12.8 vs. 53.0?
Yasmine Oladele Hardy   +13 more
wiley   +1 more source

Effects of secukinumab on enthesiophyte and erosion progression in psoriatic arthritis –a one‐year double‐blind, randomized, placebo‐controlled trial utilizing high‐resolution peripheral quantitative computed tomography

open access: yesArthritis &Rheumatology, Accepted Article.
Objectives This study aimed to ascertain the effect of secukinumab on erosion and enthesiophyte progression in psoriatic arthritis (PsA) by high‐resolution peripheral quantitative computed tomography (HR‐pQCT). Methods This was a phase 4, double‐blind, randomized, placebo‐controlled trial.
Yingzhao Jin   +11 more
wiley   +1 more source

Evaluation of ABCA1 gene polymorphism as a prognostic index of fibrosis progression in NAFLD patients

open access: yesEndocrinology, Diabetes &Metabolism, Volume 6, Issue 1, January 2023., 2023
Dyslipidemias, hepatic steatosis index, and ABCA1 (rs1800977) gene polymorphism CC genotype; were the only independent predictors of advanced fibrosis in NAFLD‐patients. Abstract Introduction It had been evident that non‐alcoholic fatty liver disease (NAFLD) is the new era epidemic.
Samar E. Ghanem   +7 more
wiley   +1 more source

Spatial and temporal distribution patterns and factors influencing hepatitis B in China: a geo-epidemiological study. [PDF]

open access: yesBMC Public Health
Fang K   +9 more
europepmc   +1 more source

Long‐Term Implications of Short‐Term Symptom and Radiographic Severity Outcomes After ESS in CRS Patients

open access: yes
International Forum of Allergy &Rhinology, EarlyView.
Aditi Agarwal   +12 more
wiley   +1 more source

Recurrence Risk in Pediatric Non‐Infectious Uveitis during Adalimumab Tapering: An International Multicenter Retrospective Study

open access: yesArthritis &Rheumatology, Accepted Article.
Objectives This study aims to assess the risk of non‐infectious uveitis (NIU) relapse in pediatric patients undergoing Adalimumab (ADA) tapering, evaluating potential predictors of such risk Methods We conducted a multicenter retrospective cohort study involving pediatric NIU patients who underwent ADA tapering due to inactive uveitis. Cox proportional
Achille Marino   +31 more
wiley   +1 more source

Hepatitis B virus infection after immunization: How serious it is? An updated review. [PDF]

open access: yesClin Exp Med
Marjani A   +6 more
europepmc   +1 more source

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