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Best practices for engaging with affected communities: chronic hepatitis B as a case study [PDF]

Infectious Diseases of Poverty
Hepatitis B is the single most common cause of liver cancer, affecting > 250 million people worldwide (mostly in resource limited communities) and killing > 1 million people annually. The condition is marked by poor rates of diagnosis (14%) and treatment
Thomas Tu, Nafisa Yussf, Lien Tran, Kim Ngo, Su Wang, Adi Mondel, Isabelle Purcell, Jacki Chen, Wendy Lo, Bright Ansah, Kenneth Kabagambe, Soumen Basu, Dee Lee, Supa Chantschool, Chris Munoz, Ivana Dragojevic, Marko Korenjak, Fiona Borondy-Jenkins, Yasmin Ibrahim, Beatrice Zovich, Chari Cohen   +20 more
doaj   +2 more sources

Health-related quality of life for adults living with hepatitis B in the United States: a qualitative assessment

Journal of Patient-Reported Outcomes, 2021
Background In 2019, an estimated 296 million people were living with chronic hepatitis B virus (HBV) globally with approximately 2.4 million living within the United States.
Catherine Freeland, Rhea Racho, Maureen Kamischke, Kate Moraras, Evangeline Wang, Chari Cohen, Stuart Kendrick   +6 more
doaj   +1 more source

Common concerns, barriers to care, and the lived experience of individuals with hepatitis B: a qualitative study

BMC Public Health, 2021
Background An estimated between 257 and 292 million people live with chronic HBV globally. While much is known about the causes, and epidemiology of HBV, little is understood about the quality of life and impact of HBV on those living with the infection.
Catherine Freeland, Sean Farrell, Priyanka Kumar, Maureen Kamischke, Michaela Jackson, Sierra Bodor, Timothy M. Block, Rosemary Frasso, Chari Cohen   +8 more
doaj   +1 more source

Alinity m, a Random-Access System, for Hepatitis B Virus DNA Quantification in Plasma and Whole Blood Collected on Dried Blood Spots

mSphere, 2022
The International Liver Association recommends the use of accurate and sensitive molecular methods for determination of hepatitis B virus (HBV) DNA levels in plasma or serum of chronic HBsAg carriers. The level of HBV replication represents the strongest
Valérie Ortonne, Quentin Lucas, Olivia Garrigou, Alexandre Soulier, Dominique Challine, Jean-Michel Pawlotsky, Vincent Leroy, Stéphane Chevaliez   +7 more
doaj   +1 more source

The unvirtuous cycle of discrimination affecting people with hepatitis B: a multi-country qualitative assessment of key-informant perspectives

International Journal for Equity in Health, 2022
Background An estimated 296 million individuals live with chronic hepatitis B worldwide, most have not been diagnosed and remain at risk of liver disease and cancer.
Catherine Freeland, Lindsay Mendola, Vivian Cheng, Chari Cohen, Jack Wallace   +4 more
doaj   +1 more source

A Novel Insertion in the Hepatitis B Virus Surface Protein Leading to Hyperglycosylation Causes Diagnostic and Immune Escape

Viruses, 2023
Chronic hepatitis B virus (HBV) infection is a global health threat. Mutations in the surface antigen of HBV (HBsAg) may alter its antigenicity, infectivity, and transmissibility.
Felix Lehmann, Heiko Slanina, Martin Roderfeld, Elke Roeb, Jonel Trebicka, John Ziebuhr, Wolfram H. Gerlich, Christian G. Schüttler, Bernhard Schlevogt, Dieter Glebe   +9 more
doaj   +1 more source

Hepatitis B, C, and delta in the general population in Mayotte: hepatitis B as a major public health concern

BMC Infectious Diseases, 2022
Background Located in southwestern Indian Ocean, Mayotte is a French territory, with a very specific demographic, social and health context. To date, epidemiological data on infections by hepatitis B (HBV), C (HCV), and delta (HDV) viruses in Mayotte ...
Cécile Brouard, Fanny Parenton, Hassani Youssouf, Stéphane Chevaliez, Emmanuel Gordien, Maxime Jean, Mathias Bruyand, Sophie Vaux, Florence Lot, Marc Ruello, Unono Wa Maore group   +10 more
doaj   +1 more source

Barriers to Hepatitis B Screening and Prevention for African Immigrant Populations in the United States: A Qualitative Study

Viruses, 2020
Chronic hepatitis B infection (HBV) disproportionately affects African Immigrant (AI) communities in the U.S., with a reported infection rate of 15%. HBV screening rates within these communities are low.
Catherine Freeland, Sierra Bodor, Udara Perera, Chari Cohen   +3 more
doaj   +1 more source

Action Mechanisms and Scientific Rationale of Using Nasal Vaccine (HeberNasvac) for the Treatment of Chronic Hepatitis B

Vaccines, 2022
Nasvac (HeberNasvac®) is a novel therapeutic vaccine for chronic hepatitis B (CHB). This product is a formulation of the core (HBcAg) and surface (HBsAg) antigens of the hepatitis B virus (HBV), administered by nasal and subcutaneous routes, in a ...
Julio Cesar Aguilar, Jorge Agustin Aguiar, Sheikh Mohammad Fazle Akbar   +2 more
doaj   +1 more source

Perceptions and patient care needs among hepatitis B patients during COVID-19

BMC Health Services Research, 2022
Background The novel coronavirus of 2019 (COVID-19) has been and continues to be a rapidly developing public health crisis, that has also disrupted routine and maintenance health care for people living with chronic conditions.
Sherrie Flynt Wallington, Min Jeong Jeon, T. Angeline Nguyen, Choosonjargal Byambaa, Y. Tony Yang, Daisy Le   +5 more
doaj   +1 more source