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2010
Chronic hepatitis B virus (HBV) infection is the most important etiologic agent of hepatocellular carcinoma (HCC) worldwide. This is remarkable, considering that the virus consists of a DNA genome that is only 3.2 kb in size and encodes proteins from only four open reading frames (ORFs), all of which are located on the same DNA strand of the virus [1].
Reis, Helena M +5 more
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Chronic hepatitis B virus (HBV) infection is the most important etiologic agent of hepatocellular carcinoma (HCC) worldwide. This is remarkable, considering that the virus consists of a DNA genome that is only 3.2 kb in size and encodes proteins from only four open reading frames (ORFs), all of which are located on the same DNA strand of the virus [1].
Reis, Helena M +5 more
openaire +2 more sources
Pediatrics, 1992
To the Editor.— As a practicing pediatrician, I have two major reservations with the current recommendations of the Committee on Infectious Diseases for universal Hepatitis B virus (HBV) immunization. The first reservation is practical, and the second is theoretical.
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To the Editor.— As a practicing pediatrician, I have two major reservations with the current recommendations of the Committee on Infectious Diseases for universal Hepatitis B virus (HBV) immunization. The first reservation is practical, and the second is theoretical.
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Current Treatment Options in Gastroenterology, 2004
Interferon alpha, lamivudine, and adefovir are the three drugs currently approved for the treatment of chronic hepatitis B virus (HBV). There are pros and cons associated with the use of each drug. Individualization of therapy, based upon factors such as patient comorbidities, response to prior therapies, and stage of disease, is recommended.
Stephanie D, Straley, Norah A, Terrault
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Interferon alpha, lamivudine, and adefovir are the three drugs currently approved for the treatment of chronic hepatitis B virus (HBV). There are pros and cons associated with the use of each drug. Individualization of therapy, based upon factors such as patient comorbidities, response to prior therapies, and stage of disease, is recommended.
Stephanie D, Straley, Norah A, Terrault
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Journal of Pediatric Health Care, 1999
Hepatitis B virus (HBV) infection is a health problem that affects numerous infants and children in the United States. Approximately 4000 to 6000 new infections occur each year in children and adolescents; most often they become infected without obvious clinical manifestations. Some persons become chronically infected, and this asymptomatic chronically
M J, Ott, M, Aruda
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Hepatitis B virus (HBV) infection is a health problem that affects numerous infants and children in the United States. Approximately 4000 to 6000 new infections occur each year in children and adolescents; most often they become infected without obvious clinical manifestations. Some persons become chronically infected, and this asymptomatic chronically
M J, Ott, M, Aruda
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Journal of Hepatology, 2003
Yeast-derived hepatitis B vaccines, containing the small HBV envelope protein SHBAg, are immunogenic, safe and cost-effective in prevention of hepatitis B virus infection in neonates, children and adults. Newly developed pre-S/S hepatitis B vaccines may play a role in inducing fast and augmented seroconversion rates in special risk groups.
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Yeast-derived hepatitis B vaccines, containing the small HBV envelope protein SHBAg, are immunogenic, safe and cost-effective in prevention of hepatitis B virus infection in neonates, children and adults. Newly developed pre-S/S hepatitis B vaccines may play a role in inducing fast and augmented seroconversion rates in special risk groups.
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Transplantation Proceedings, 2013
There is an extremely high burden of liver disease owing to viral hepatitis B (HBV); about 2 billion people are infected and 350 million are chronic carriers of HBV worldwide. More effective medical therapy and liver transplantation are available for those with advancing disease.
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There is an extremely high burden of liver disease owing to viral hepatitis B (HBV); about 2 billion people are infected and 350 million are chronic carriers of HBV worldwide. More effective medical therapy and liver transplantation are available for those with advancing disease.
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Journal of Virological Methods, 1985
As hepatitis B virus does not replicate in tissue culture systems, it was impossible to prepare a vaccine in the conventional way. However, the surface-antigen of the virus is present in abundance in the blood of certain virus carriers. This phenomenon has been used to develop plasma-derived hepatitis B vaccines and these vaccines are now available. In
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As hepatitis B virus does not replicate in tissue culture systems, it was impossible to prepare a vaccine in the conventional way. However, the surface-antigen of the virus is present in abundance in the blood of certain virus carriers. This phenomenon has been used to develop plasma-derived hepatitis B vaccines and these vaccines are now available. In
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Vaccine, 1983
Abstract Hepatitis B is endemic in many African, Asian and Pacific countries causing much debilitation and death. The disease can lead to chronic cirrhosis and is closely associated with liver cell cancer. There are in the order of 200 million people that carry the virus and constitute a huge reservoir of infection.
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Abstract Hepatitis B is endemic in many African, Asian and Pacific countries causing much debilitation and death. The disease can lead to chronic cirrhosis and is closely associated with liver cell cancer. There are in the order of 200 million people that carry the virus and constitute a huge reservoir of infection.
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Cell entry and release of quasi-enveloped human hepatitis viruses
Nature Reviews Microbiology, 2023, Xin Yin, Christopher Walker
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