Results 231 to 240 of about 184,721 (306)

Temporal trends in transfusion-transmissible infections among blood donors in Jordan: A large-scale Amman-based surveillance update (2018-2019). [PDF]

Medicine (Baltimore)
Atoom A, Al-Abadi B, Al-Hiary M, Alzubi B, Al-Saeidat S, Al-Qaisi T.   +5 more
europepmc   +1 more source

Disease Progression Mathematical Modeling With a Case Study on Hepatitis B Virus Infection

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 420-434, March 2025.
ABSTRACT Chronic Hepatitis B presents a significant health and socioeconomic burden. The risk of hepatocellular carcinoma remains elevated although treatments are available. Achieving an optimal treatment regimen necessitates a deep comprehension of the dynamic relationship between the virus and its host across disease states.
Clémence Boivin‐Champeaux, Nieves Velez de Mendizabal, Aksana Jones, Scott Balsitis, Stephan Schmidt, Justin S. Feigelman, Francine Johansson Azeredo   +6 more
wiley   +1 more source

Serologic Evidence of Circulation of Six Arboviruses (Dengue Virus, Chikungunya Virus, Zika Virus, Rift Valley Virus, Yellow Fever Virus, Crimean-Congo Hemorrhagic Fever Virus) in Four Regions of Burkina Faso, West Africa. [PDF]

Trop Med Infect Dis
Sanou AM, Nikiéma AS, Sausy A, Diendéré J, Ouattara MNG, Badiel ABS, Bonkoungou I, Ouédraogo HG, Hübschen JM.   +8 more
europepmc   +1 more source

A Quantitative Systems Pharmacology (QSP) Model of Acute Hepatitis B Virus Infection: Mechanistic Insights and Foundations for Future Extensions

CPT: Pharmacometrics &Systems Pharmacology, EarlyView.
ABSTRACT Chronic hepatitis B virus (HBV) infection remains a significant global health challenge. While the dynamic interplay between viral replication and host immune responses determines infection outcomes, the mechanisms driving the resolution of acute infection versus the emergence of chronicity remain incompletely understood.
Clémence Boivin‐Champeaux, Stephan Schmidt, Scott Balsitis, Francine Johansson Azeredo, Justin S. Feigelman   +4 more
wiley   +1 more source

A Double-Edged Sword: The Clinical Dilemma of Lupus Nephritis and Antineutrophil Cytoplasmic Antibody-Associated Vasculitis Overlap Syndrome. [PDF]

Cureus
Probasco L, Fernandez Placencia AC.
europepmc   +1 more source

Nature Inspired Delivery Vehicles for CRISPR‐Based Genome Editing

Small, EarlyView.
The review highlights nature‐inspired nanocarriers for CRISPR delivery, emphasizing viral vectors, extracellular vesicles, liposomes, and lipid nanoparticles. It discusses their roles in improving specificity, minimizing immunogenicity, and overcoming barriers in genome editing. Recent advancements, challenges, and therapeutic applications are explored,
Elizabeth Maria Clarissa, Mamata Karmacharya, Hyunmin Choi, Sumit Kumar, Yoon‐Kyoung Cho   +4 more
wiley   +1 more source

Catatonia as the initial manifestation of neuropsychiatric lupus. [PDF]

Oxf Med Case Reports
Lucas-Hernández A, Hernández-Sánchez BE, Rojas-Xicohténcatl A, Lucas-Lerdo JM, Hernández-Barre Z, Peralta-Amaro AL.   +5 more
europepmc   +1 more source

Novel Wide‐Spectrum Virucidal Lipid Nanoparticles

Small, EarlyView.
POSTAN is a novel broad‐spectrum antiviral nanoparticle that combines safety with potent virucidal activity. Composed of biocompatible lipids, it mimics heparan sulfate proteoglycans and lipid rafts exploited by viruses, thereby dismantling viral envelopes and blocking replication.
Yugo Araújo Martins, Louise Bondeelle, Arnaud Charles‐Antoine Zwygart, Thais Melquiades de Lima, Juliano de Paula Souza, Han Kang Tee, Fernando Chahud, Eurico de Arruda Neto, Francesco Stellacci, Renata Fonseca Vianna Lopez, Caroline Tapparel   +10 more
wiley   +1 more source

Preliminary Case-Control Study of Antibody Response to Vaccines in Children on bDMARDs. [PDF]

Children (Basel)
Demirbuğa A, Dede E, Akgün Karapınar DB, Kaba Ö, Mete Atasever N, Durmuş MA, Önel M, Ağaçfidan A, Somer A, Hançerli Törün S.   +9 more
europepmc   +1 more source

Beads‐on‐a‐Tip testing for ultrasensitive antigen detection across a large dynamic range

Smart Molecules, EarlyView.
Non‐specific adsorption on nitrocellulose membranes limits the sensitivity of conventional lateral flow immunoassays. Here, we present a Beads‐on‐a‐Tip immunoassay that replaces the membrane with magnetic beads for antigen capture and enrichment, while employing upconversion nanoparticles as background‐free luminescent reporters.
Ziwei Wu, Yangjian Cai, Yitong Zhao, Mahnaz Maddahfar, Mohammad Sadraeian, Dayong Jin, Jiajia Zhou   +6 more
wiley   +1 more source