Results 1 to 10 of about 281,611 (124)

Positive HBs antigen in the absence of hepatitis B virus infection [PDF]

Annales de Biologie Clinique, John Libbey Eurotext, 2019, 77 (5), pp.543-548, 2019
French recommendations for the screening of hepatitis B virus (HBV) infection were updated in 2019 with the association of three markers: HBs Ag, anti-HBs Ab and anti-HBc Ab. These three markers allow identification of infected patients, vaccinated patients and patients who have been in contact with HBV. A positive HBs Ag is usually associated with HBV
arxiv   +1 more source

Adaptive Learning Expert System for Diagnosis and Management of Viral Hepatitis [PDF]

International journal of artificial intelligence and applications, 2019, Volume 10, Number 2, 2019
Viral hepatitis is the regularly found health problem throughout the world among other easily transmitted diseases, such as tuberculosis, human immune virus, malaria and so on. Among all hepatitis viruses, the uppermost numbers of deaths are result from the long-lasting hepatitis C infection or long-lasting hepatitis B. In order to develop this system,
arxiv   +1 more source

Mathematical Analysis of Autonomous and Nonautonomous Hepatitis B Virus Transmission Models [PDF]

, 2023
This study presents an improved mathematical model for Hepatitis B Virus (HBV) transmission dynamics by investigating autonomous and nonautonomous cases. The novel model incorporates the effects of medical treatment, allowing for a more comprehensive understanding of HBV transmission and potential control measures.
arxiv   +1 more source

Dynamical analysis of a generalized hepatitis B epidemic model and its dynamically consistent discrete model [PDF]

arXiv, 2021
The aim of this work is to study qualitative dynamical properties of a generalized hepatitis B epidemic model and its dynamically consistent discrete model.
arxiv  

The effects of symmetry on the dynamics of antigenic variation [PDF]

J. Math. Biol. 66, 115-137 (2013), 2012
In the studies of dynamics of pathogens and their interactions with a host immune system, an important role is played by the structure of antigenic variants associated with a pathogen. Using the example of a model of antigenic variation in malaria, we show how many of the observed dynamical regimes can be explained in terms of the symmetry of ...
arxiv   +1 more source

Molecular tug of war reveals adaptive potential of an immune cell repertoire [PDF]

arXiv, 2022
The adaptive immune system constantly remodels its lymphocyte repertoire for better protection against future pathogens. Its ability to improve antigen recognition on the fly relies on somatic mutation and selective expansion of B lymphocytes expressing high-affinity antigen receptors.
arxiv  

Active tuning of synaptic patterns enhances immune discrimination [PDF]

Phys. Rev. Lett. 121, 238101 (2018), 2018
Immune cells learn about their antigenic targets using tactile sense: during recognition, a highly organized yet dynamic motif, named immunological synapse, forms between immune cells and antigen-presenting cells (APCs). Via synapses, immune cells selectively extract recognized antigen from APCs by applying mechanical pulling forces generated by the ...
arxiv   +1 more source

Mathematical model of immune response to hepatitis B [PDF]

J. Theor. Biol. 447, 98-110 (2018), 2018
A new detailed mathematical model for dynamics of immune response to hepatitis B is proposed, which takes into account contributions from innate and adaptive immune responses, as well as cytokines. Stability analysis of different steady states is performed to identify parameter regions where the model exhibits clearance of infection, maintenance of a ...
arxiv   +1 more source

Textual analysis of clinical notes on pathology request forms to determine sensitivity and specificity of Hepatitis B and C virus infection status [PDF]

arXiv, 2022
Background: It is not established whether clinical notes provided on pathology request forms are useful as decision support data when assessing Hepatitis B and C viral infection status. Objective: To determine sensitivity, specificity, and predictive value of clinical notes for identifying infection status of Hepatitis B and C.
arxiv  

Method for identification of condition-associated public antigen receptor sequences [PDF]

eLife 2018;7:e33050, 2017
Diverse repertoires of hypervariable immunoglobulin receptors (TCR and BCR) recognize antigens in the adaptive immune system. The development of immunoglobulin receptor repertoire sequencing methods makes it possible to perform repertoire-wide disease association studies of antigen receptor sequences.
arxiv   +1 more source