Results 181 to 190 of about 553,116 (313)

Covalent drug discovery: Progress against key targets, emerging strategies and lessons learnt

British Journal of Pharmacology, EarlyView.
Abstract Covalent drug discovery is currently experiencing a boom in industrial and academic interest. To date, at least 75 covalent drugs have received regulatory approval, targeting both traditional target classes and more challenging proteins for which other approaches failed. In many cases, unique aspects of covalent targeting are essential for the
Charles P. Brown, Alan Armstrong, David J. Mann   +2 more
wiley   +1 more source

Lipid Nanoparticle-Encapsulated PolyI:C as an Adjuvant Enhances Both Humoral and Cellular Immune Responses to the Hepatitis B Vaccine. [PDF]

Vaccines (Basel)
Zhao Z, Wang B, Wang H, Zhang Q, Liang Y, Liu Y.   +5 more
europepmc   +1 more source

The immune response during hepatitis B virus infection.

Journal of General Virology, 2006
A. Bertoletti, A. Gehring
semanticscholar   +1 more source

Therapeutic potential of natural products in cancer immunotherapy: Advances and challenges

British Journal of Pharmacology, EarlyView.
This review systematically outlines the mechanisms underlying tumour immunotherapy resistance and elucidates the role of natural products in enhancing therapeutic efficacy as immunomodulatory adjuvants. Abstract Immunotherapy has emerged as a clinically pivotal approach in cancer treatment, but its application remains limited to a small subset of ...
Rao Hu, Kaibin Dai, Zhensheng Lin, Mingfang Ye, Minfeng Chen, Xiaobo Li, Dongmei Zhang   +6 more
wiley   +1 more source

Trends in clinical intervention practice for preventing mother-to-child transmission of hepatitis B virus in Guangdong Province, 2021-2023. [PDF]

Hum Vaccin Immunother
Gao S, Xie T, Cai M, Su M, Zhao T, Zhang X, Zhang S, Wang M, Xu Q, Cheng Y, Cui F, Liu F.   +11 more
europepmc   +1 more source

Lamivudine treatment can restore T cell responsiveness in chronic hepatitis B.

Journal of Clinical Investigation, 1998
C. Boni, A. Bertoletti, A. Penna, A. Cavalli, M. Pilli, S. Urbani, P. Scognamiglio, R. Boehme, R. Panebianco, F. Fiaccadori, C. Ferrari   +10 more
semanticscholar   +1 more source

Perspectives on Pertussis Prevention

Acta Paediatrica, EarlyView.
Ulrich Heininger
wiley   +1 more source

Cardiovascular toxicity from immune checkpoint inhibitor therapy: an inflammatory continuum

British Journal of Pharmacology, EarlyView.
Immune checkpoint inhibitor (ICI) therapy has markedly improved outcomes in advanced malignancies but has also revealed a distinct spectrum of cardiovascular immune‐related adverse events. Myocarditis represents the most severe manifestation, while non‐inflammatory left ventricular dysfunction and vascular inflammation have emerged as additional ...
Fabrice Reyes, Florian Buehning, Tobias Lerchner, Julia Vogel, Raluca I. Mincu, Matthias Totzeck, Tienush Rassaf, Lars Michel   +7 more
wiley   +1 more source

Virus Biomimetic-Delivery Systems for the Production of Vaccines. [PDF]

Biomimetics (Basel)
Barbinta-Patrascu ME, Negut I, Bita B.
europepmc   +1 more source

Association between an MHC class II allele and clearance of hepatitis B virus in the Gambia.

New England Journal of Medicine, 1995
Atherine, A. E.M, Llsopp, Rian, G. M., Reenwood, Oward, T. C, Homas   +8 more
semanticscholar   +1 more source