Hepatitis B virus pre‐S mutants, endoplasmic reticulum stress and hepatocarcinogenesis
Hui-Ching Wang +3 more
semanticscholar +1 more source
Epigenetic Regulation of Liver Fibrosis: Mechanisms and Therapeutic Implications
This review synthesizes the epigenetic mechanisms—DNA methylation, histone modifications, and non‐coding RNAs—that drive hepatic stellate cell activation and the progression of liver fibrosis. It further evaluates emerging therapeutic strategies targeting these epigenetic regulators, including DNA methyltransferase and histone deacetylase inhibitors ...
Maryam Jadid Tavaf +8 more
wiley +1 more source
Progress and challenge of hepatitis B virus mucosal vaccines. [PDF]
Renxuan J, Hongxiang L, Daru L.
europepmc +1 more source
Recompensation of Cirrhosis: A New Treatment‐Related Disease State
This perspective article conceptualizes recompensation of cirrhosis as a distinct treatment‐related disease state rather than mere transient clinical improvement after etiology‐directed therapy, and further proposes a four‐state classification including compensated cirrhosis, stable recompensation, unstable recompensation, and persistent decompensation
Wentao Tan +5 more
wiley +1 more source
Sequential combination of anti-PD-1 antibody and PEG-IFNα in chronic hepatitis B patients: correlates of HBsAg loss with enhanced T-cell responses. [PDF]
Wang H +15 more
europepmc +1 more source
This perspective outlines China's contributions toward functional‐cure‐oriented antiviral therapies for chronic hepatitis B, summarizing key clinical data on bepirovirsen and domestic drug pipelines with balanced coverage of both promising and disappointing trial results.
Dandan Weng, Zhujun Cao, Qing Xie
wiley +1 more source
Risk factors for postpartum alanine aminotransferase elevation in women with chronic hepatitis B infection: a systematic review and meta-analysis. [PDF]
Yao C +7 more
europepmc +1 more source
Immunogenicity of transgenic plant-derived hepatitis B surface antigen.
Y. Thanavala +4 more
semanticscholar +1 more source
Disease Progression Mathematical Modeling With a Case Study on Hepatitis B Virus Infection
ABSTRACT Chronic Hepatitis B presents a significant health and socioeconomic burden. The risk of hepatocellular carcinoma remains elevated although treatments are available. Achieving an optimal treatment regimen necessitates a deep comprehension of the dynamic relationship between the virus and its host across disease states.
Clémence Boivin‐Champeaux +6 more
wiley +1 more source

