Results 31 to 40 of about 420,842 (369)

Modulation of antigen-specific T-cells as immune therapy for chronic infectious diseases and cancer [PDF]

, 2014
Copyright: © 2014 Li, Symonds, Miao, Sanderson and Wang. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY).
Abraham, Ahmadzadeh, Akbar, Anderson, Baine, Barber, Baur, Belkaid, Bensinger, Bergmann, Berzofsky, Blackburn, Brooks, Brooks, Brooks, Colonna, Das, Day, Duraiswamy, Ejrnaes, Frebel, Geijtenbeek, Guidotti, Ha, Jerome, Jung, Kasprowicz, Kaufmann, Kim, Klein, Kroemer, Kroy, Larsson, Liu, Lu, Maizels, Malek, Matsuzaki, Mier, Mumprecht, Nandedkar, Nurieva, Nurieva, Ramsay, Schietinger, Schwartz, Sofra, Soldaini, Steinman, Trautmann, Vezys, Waggoner, Wedemeyer, Wilson, Yi, Zhou   +55 more
core   +2 more sources

Linearized hepatitis B surface antigen and hepatitis B core-related antigen in the natural history of chronic hepatitis B [PDF]

Clinical Microbiology and Infection, 2014
Changes in two novel HBV serological markers, linearized hepatitis B surface antigen (HQ-HBsAg) and hepatitis B core-related antigen (HBcrAg), in the natural history of chronic hepatitis B (CHB) have not been well characterized. Serum HQ-HBsAg and HBcrAg levels of 404 Asian treatment-naïve CHB patients were analysed in a cross-sectional manner ...
Wong, DKH, Seto, WKW, Fung, JYY, Huang, FY, Liu, KS, Lai, CL, Yuen, RMF   +6 more
openaire   +5 more sources

Seroprevalence of hepatitis B infection and associated risk factors among drug users in drop-in centers of Isfahan, Iran

International Journal of Preventive Medicine, 2018
Background: Scientists perceive drug users (DUs) as a high-risk population for hepatitis B virus (HBV) infection. Effective strategies aiming at the reduction of HBV infection can be depicted when its epidemiological status is clearly defined.
Roya Taleban, Mohammad Moafi, Behrooz Ataei, Majid Yaran, Zary Nokhodian, Nazila Kassaian, Peyman Adibi, Abbasali Javadi   +7 more
doaj   +1 more source

Molecular tug of war reveals adaptive potential of an immune cell repertoire [PDF]

arXiv, 2022
The adaptive immune system constantly remodels its lymphocyte repertoire for better protection against future pathogens. Its ability to improve antigen recognition on the fly relies on somatic mutation and selective expansion of B lymphocytes expressing high-affinity antigen receptors.
arxiv  

Active tuning of synaptic patterns enhances immune discrimination [PDF]

Phys. Rev. Lett. 121, 238101 (2018), 2018
Immune cells learn about their antigenic targets using tactile sense: during recognition, a highly organized yet dynamic motif, named immunological synapse, forms between immune cells and antigen-presenting cells (APCs). Via synapses, immune cells selectively extract recognized antigen from APCs by applying mechanical pulling forces generated by the ...
arxiv   +1 more source

Serum hepatitis B virus RNA levels as a predictor of HBeAg seroconversion during treatment with peginterferon alfa-2a

Virology Journal, 2019
Background Hepatitis B e antigen (HBeAg) seroconversion represents an endpoint of treatment of chronic hepatitis B virus (HBV) infections. Methods We have studied whether levels of serum hepatitis B virus ribonucleic acid (HBV RNA) during pegylated ...
Wen Jia, Men Qi Zhu, Xun Qi, Ting Wang, Xiao Wen, Pei Dong Chen, Qing Qi Fan, Wen-Hong Zhang, Ji Ming Zhang   +8 more
doaj   +1 more source

Mathematical model of immune response to hepatitis B [PDF]

J. Theor. Biol. 447, 98-110 (2018), 2018
A new detailed mathematical model for dynamics of immune response to hepatitis B is proposed, which takes into account contributions from innate and adaptive immune responses, as well as cytokines. Stability analysis of different steady states is performed to identify parameter regions where the model exhibits clearance of infection, maintenance of a ...
arxiv   +1 more source

A simple device for multiplex ELISA made from melt-extruded plastic microcapillary film [PDF]

, 2011
We present a simple device for multiplex quantitative enzyme-linked immunosorbant assays (ELISA) made from a novel melt-extruded microcapillary film (MCF) containing a parallel array of 200µm capillaries along its length.
Abramoff, Alexander D. Edwards, Bange, Chin, Choi, de Frutos, Gervais, Gorkin, Hallmark, Henares, Honda, Ikami, Kim, Koch, Lee, Leis, Lim, Malcolm R. Mackley, Martinez, Mastichiadis, Mastichiadis, Medina, Myers, Nigel K. H. Slater, Nuno M. Reis, Petrou, Rivet, Schroeder, Yacoub-George, Yager   +29 more
core   +2 more sources

Textual analysis of clinical notes on pathology request forms to determine sensitivity and specificity of Hepatitis B and C virus infection status [PDF]

arXiv, 2022
Background: It is not established whether clinical notes provided on pathology request forms are useful as decision support data when assessing Hepatitis B and C viral infection status. Objective: To determine sensitivity, specificity, and predictive value of clinical notes for identifying infection status of Hepatitis B and C.
arxiv  

Method for identification of condition-associated public antigen receptor sequences [PDF]

eLife 2018;7:e33050, 2017
Diverse repertoires of hypervariable immunoglobulin receptors (TCR and BCR) recognize antigens in the adaptive immune system. The development of immunoglobulin receptor repertoire sequencing methods makes it possible to perform repertoire-wide disease association studies of antigen receptor sequences.
arxiv   +1 more source