Results 41 to 50 of about 420,842 (369)

Immunotherapy in hepatocellular carcinoma: the complex interface between inflammation, fibrosis, and the immune response. [PDF]

open access: yes, 2019
Hepatocellular carcinoma (HCC) is the third leading cause of cancer deaths worldwide and confers a poor prognosis. Beyond standard systemic therapy with multikinase inhibitors, recent studies demonstrate the potential for robust and durable responses ...
Fong, Lawrence   +2 more
core   +2 more sources

Antibody responses to Hepatitis B and measles-mumps-rubella vaccines in children who received chemotherapy for acute lymphoblastic leukemia

open access: yesRevista Brasileira de Hematologia e Hemoterapia, 2012
OBJECTIVE: To evaluate viral vaccine antibody levels in children with acute lymphoblastic leukemia after chemotherapy and after vaccine booster doses.
Simone Santana Viana   +5 more
doaj   +1 more source

Evaluation of the immune response to RTS,S/AS01 and RTS,S/AS02 adjuvanted vaccines : randomized, double-blind study in malaria-naïve adults [PDF]

open access: yes, 2014
This phase II, randomized, double-blind study evaluated the immunogenicity of RTS, S vaccines containing Adjuvant System AS 01 or AS 02 as compared with non-adjuvanted RTS, S in healthy, malaria-naive adults (NCT00443131).
Ballou, W Ripley   +8 more
core   +2 more sources

Outcomes of hepatitis B immunoglobulin and hepatitis B vaccination in high-risk newborns born to HBeAg-positive mothers

open access: yesBiomedical Journal, 2022
Background: To evaluate the protective efficacy of a hepatitis B (HB) vaccination program in Taiwan among high-risk children. Methods: Children born to HBeAg-positive mothers from 2001 to 2010 were invited back.
Chen-Hsuan Wu   +3 more
doaj  

HBsAg-vectored DNA vaccines elicit concomitant protective responses to multiple CTL epitopes relevant in human disease. [PDF]

open access: yes, 2008
Vaccines capable of controlling neoplastic and infectious diseases which depend on the cellular immune response for their resolution, have proven difficult to develop.
Allan Gould   +7 more
core   +1 more source

Monoclonal Antibodies Specific for Hepatitis B e Antigen and Hepatitis B Core Antigen

open access: yesHybridoma, 2011
Despite effective vaccination programs in many countries, HBV infection is still a serious health problem throughout the world; more than 2 billion people have been infected with Hepatitis B virus (HBV). The serologic markers are crucial indicators in clinical diagnosis of HBV infection. The persistent presence of anti-HBc is associated with chronicity,
Sogut, Ibrahim   +3 more
openaire   +4 more sources

Hepatitis B e antigen-negative chronic hepatitis B [PDF]

open access: yesHepatology, 2001
Summary HBeAg-negative CHB has now a worldwide distribution, developing in the course of HBeAg-positive chronic HBV infection during or after the phase of HBeAg loss and its seroconversion to anti-HBe. It is caused by replicating noncytopathic HBV mutants either unable to produce HBeAg (precore mutants) or with down-regulated transcription of the ...
Dimitrios Vassilopoulos   +1 more
openaire   +3 more sources

Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia

open access: yesFEBS Letters, EarlyView.
This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley   +1 more source

A recombinant human immunoglobulin with coherent avidity to hepatitis B virus surface antigens of various viral genotypes and clinical mutants.

open access: yesPLoS ONE, 2020
The hepatitis B virus (HBV) envelope is composed of a lipid bilayer and three glycoproteins, referred to as the large (L), middle (M), and small (S) hepatitis B virus surface antigens (HBsAg). S protein constitutes the major portion of the viral envelope
Gi Uk Jeong   +8 more
doaj   +1 more source

Особенности распространения эритроцитарных групповых антигенов среди инфицированных гепатитом “В” и “С” и здоровых доноров [PDF]

open access: yes, 2010
Вивчено зв’язок між еритроцитарними антигенами системи АВО та вірусними (B и C) гепатитами. Встановлено, що до інфікування гепатитом В схильні носії A(II) фенотипної групи, RhD фактору, антигену С як у гетерозиготному (Сс), так і особливо у гомозиготному
Ахвледиани, Л.   +1 more
core  

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