Results 81 to 90 of about 281,611 (124)

Electrochemical sensing strategies for on‐site testing of pathogenic nucleic acids

Electrochemical Science Advances, EarlyView.
Abstract Rapid and reliable on‐site pathogen testing is crucial for diagnosing and managing human health. Nucleic acids (NAs) containing genetic information are valuable target molecules for pathogen testing, and sensitive and rapid detection of NAs using electrochemical approaches has been intensively investigated.
Yusuke Kanno, Shuzo Masui, Yusuke Ota, Ryoichi Saito, Takasi Nisisako   +4 more
wiley   +1 more source

Role of RNA modifications in carcinogenesis and carcinogen damage response

Molecular Carcinogenesis, Volume 62, Issue 1, Page 24-37, January 2023., 2023
Abstract The field of epitranscriptomics encompasses the study of post‐transcriptional RNA modifications and their regulatory enzymes. Among the numerous RNA modifications, N6‐methyladenosine (m6A) has been identified as the most common internal modification of messenger RNA (mRNA).
Michelle Verghese, Emma Wilkinson, Yu‐Ying He   +2 more
wiley   +1 more source

Comprehensive Insights Into Genetically Modified Foods: Technological Advances, Nutritional Benefits, Therapeutic Applications, and Health Implications

Food Safety and Health, EarlyView.
This graphical abstract highlights the benefits of genetically modified (GM) foods, including high‐yield crops such as golden rice with enhanced nutrition, GM vaccines, and biofuel production. Advanced analytical methods ensure safety by detecting allergenicity and toxicity, promoting sustainability while addressing environmental impacts and balancing ...
Mohamad Warda, Samet Tekin, Nagwa Khafaga, Emin Sengul, Fikret Çelebi, Burak Batuhan Laçin   +5 more
wiley   +1 more source

The compound heterozygous mutations of c.607G>a and c.657delC in the FAH gene are associated with renal damage with hereditary tyrosinemia type 1 (HT1)

Molecular Genetics &Genomic Medicine, Volume 11, Issue 1, January 2023., 2023
This study demonstrated the novel compound heterozygous mutations (NM_000137: c.657delC (p.K220Rfs*12) and NM_000137: c.607G>A(p.A203T)) in FAH gene in a patient were responsible for HT1. We showed these FAH mutations were inherited in an autosomal recessive manner and resulted in abnormal FAH protein expression and dysfunction, leading to ...
Huan Chi, Chun Gan, Yaru Jiang, Dan Chen, Jiawen Qiu, Qing Yang, Yaxi Chen, Mo Wang, Haiping Yang, Wei Jiang, Qiu Li   +10 more
wiley   +1 more source

Isolation and Extraction of Gentian Polysaccharide and Its Protective Effect on Chemical Liver Injury

Food Safety and Health, EarlyView.
The water‐soluble polysaccharide GSBP‐N‐a‐1 with an average molecular weight of 3.82 kDa was successfully isolated and purified from Gentiana scabra. It was confirmed that the crude polysaccharides of Gentiana scabra could inhibit oxidative stress and inflammatory response by activating the Nrf2‐HO‐1 pathway, and significantly alleviate the chemical ...
Tianjiao Fu, Yan Dong, Guangxin Yuan
wiley   +1 more source

Advancing Food Safety in Bangladesh: Challenges and the Promise of Smart Sensor Technology

Food Safety and Health, EarlyView.
This study critically analyzes prevalent food safety hazards in Bangladesh and identifies key challenges in food safety practices and regulations. It discusses factors influencing food safety and explores strategies to enhance public health. Additionally, advancements in smart sensor‐based detection methods for food hazards are highlighted to offer ...
Md Wadud Ahmed, Mohammed Kamruzzaman
wiley   +1 more source

Nurse practitioner model of care for the initiation of pre‐exposure prophylaxis: A case series study

Nursing Open, Volume 10, Issue 2, Page 1135-1143, February 2023., 2023
Abstract Aim The purpose of this study was to create and implement a nurse practitioner model of care in the initiation of a pre‐exposure prophylaxis (PrEP) protocol with African American men who have sex with men (MSM). Design A case series design was used to implement the protocol for a nurse practitioner PrEP‐based model of care.
Judith B. Cornelius, Laura H. Gunn, Cynthia Dalton, Bernard Davis   +3 more
wiley   +1 more source

Silver Nanoparticle‐Mediated Antiviral Efficacy against Enveloped Viruses: A Comprehensive Review

Global Challenges, EarlyView.
Silver nanoparticles (AgNPs) exhibit broad‐spectrum antiviral activity by targeting key viral structures and processes. They disrupt viral envelopes, compromising integrity, and bind to nucleocapsids, impairing viral replication. AgNPs also inhibit glycoprotein interactions, preventing viral attachment and entry into host cells.
Ekaterine Mosidze, Gianluigi Franci, Federica Dell'Annunziata, Nicoletta Capuano, Marica Colella, Flora Salzano, Massimiliano Galdiero, Aliosha Bakuridze, Veronica Folliero   +8 more
wiley   +1 more source

CAQ Corner: Basic concepts of transplant immunology

, 2022
Liver Transplantation, EarlyView.
Amanda Cheung, Josh Levitsky
wiley   +1 more source

CAQ Corner: Immune‐mediated complications

, 2022
Liver Transplantation, EarlyView.
Mary Thomson, John R. Lake
wiley   +1 more source