Results 61 to 70 of about 14,427,656 (303)

Tracking the source of the hepatitis B virus-specific CD8 T cells during lamivudine treatment [PDF]

, 2003
Lamivudine treatment in chronic hepatitis B leads to the reconstitution of virus-specific T cells in the circulation, but it is not clear whether this is the preferential result of T cell efflux from the liver or lymph nodes.
Gotto, J, Williams, R, Webster, GJM, Dusheiko, GM, Bertoletti, A, Malacarne, F, Reignat, S, Behboudi, S, Burroughs, AK   +8 more
core  

Dual Blockade of LILRB1 and LILRB2 Enhances Antiviral Immune Responses in SIV Infection

Advanced Science, EarlyView.
Dual LILRB1/B2 blockade with mac20G10 reshapes myeloid activation during acute SIV infection by targeting LILRB1 and LILRB2 on myeloid cells. This treatment enhances CD80 expression on selected myeloid subsets and increases plasma IFN‐λ, IL‐8, and IL‐1RA.
Florian Meurisse, Sixtine Coindre, Anne Wijkhuisen, Romain Marlin, Laure Fournier Le Ray, Juliette Pons, Melyssa Yaugel‐Novoa, Véronique Avettand‐Fenoel, Laurent Abi‐Rached, Anne‐Sophie Gallouet, Francis Relouzat, Mael Gourves, Asier Saez‐Cirion, Hisashi Arase, Gerard Zurawski, Sandra Zurawski, Nathalie Dereuddre‐Bosquet, Roger Le Grand, Stéphanie Simon, Olivier Lambotte, Benoit Favier   +20 more
wiley   +1 more source

Distinct Microbial Communities in Dilated Cardiomyopathy Explanted Hearts Are Associated With Different Myocardial Rejection Outcomes

Frontiers in Cellular and Infection Microbiology, 2021
BackgroundIdiopathic dilated cardiomyopathy (IDCM) myocardial inflammation may be associated with external triggering factors such as infectious agents.
Jaqueline de Jesus Pereira, Jaqueline de Jesus Pereira, Renata Nishiyama Ikegami, Renata Nishiyama Ikegami, Joyce Tiyeko Kawakami, Joyce Tiyeko Kawakami, Shérrira Menezes Garavelo, Shérrira Menezes Garavelo, Marcia Martins Reis, Marcia Martins Reis, Suely Aparecida Pinheiro Palomino, Suely Aparecida Pinheiro Palomino, Sandrigo Mangini, Camila Rodrigues Moreno, Camila Rodrigues Moreno, Samar Freschi de Barros, Aline Rodrigues Souza, Aline Rodrigues Souza, Maria de Lourdes Higuchi, Maria de Lourdes Higuchi   +19 more
doaj   +1 more source

Determination of Relative Frequency of HBS Ag, HCV and HIV Antibodies Serum Markers among Admitted Intravenous Drug Users in Infectious Disease Ward of Razi Hospital in Ahvaz, 2004-2005

Journal of Community Health Research, 2012
Introduction: Intravenous drug users as a serious health problem in communities have economical and social effects as well as health and hygienic complications.
Abdolrasool Nikkhooy, Mohammad Nikkhooy, Nasrin Saadati   +2 more
doaj  

The prevalence of transfusion-transmitted infections and nucleic acid testing among blood donors in Majmaah, Saudi Arabia

Journal of Infection and Public Health, 2018
Background: Few studies discussed the prevalence of TTIs in Saudi donor blood samples. Thus, this study investigated the prevalence of hepatitis B virus (HBV), hepatitis C virus (HCV), human immunodeficiency virus (HIV), human T-lymphotropic virus (HTLV),
Mohammed Alaidarous, Ranjay K. Choudhary, Mohamed I. Waly, Shabir Mir, Abdulaziz Bin Dukhyil, Saeed S. Banawas, Bader M. Alshehri   +6 more
doaj   +1 more source

Dendritic cell function in the setting of chronic hepatitis c infection and changes during antiviral treatment [PDF]

, 2009
The role of the innate immune system and in particular of dendritic cells, in the establishment of chronic hepatitis C has been studied quite extensively over the last few years but controversy remains as to whether a potential virus-induced defect in
Pachiadakis, I.
core  

Chronic HBV Infection Disrupts CCL5‐Secreting cNK Cells and Attenuates Liver Accumulation and Activation of DCs and HBV‐Specific T Cells

Advanced Science, EarlyView.
ADORA2A activation suppresses NFκB‐dependent CCL5 production in cNK cells during chronic HBV infection, disrupting intrahepatic DC recruitment and HBV‐specific CD8+ T‐cell differentiation and function. Targeting the ADORA2A/NFκB/CCL5 axis restores antiviral immunity and facilitates HBV clearance.
Ailu Yang, Yucan Wang, Yating Yu, Jing Wu, Cuiping Bao, Zixuan Wang, Qiuju Han, Zhigang Tian, Jian Zhang, Huajun Zhao   +9 more
wiley   +1 more source

EBV‐Driven ODC1 Upregulation Enhances Polyamine Anabolism to Promote Viral Replication and Cisplatin Resistance in Nasopharyngeal Carcinoma

Advanced Science, EarlyView.
EBV‑BZLF1 initiates ODC1‑driven polyamine anabolism that correlates with poor clinical prognosis in nasopharyngeal carcinoma. The ODC1–spermidine axis promotes viral replication, cell proliferation and innate immune evasion. Pharmacological inhibition of ODC1 rescues cisplatin sensitivity, establishing ODC1 as a viable therapeutic target for EBV ...
Yueshuo Li, Xudong Hu, Chenxing Yang, Na Liu, Lin Wang, Xi Cai, Min Tang, Ya Cao, Li Shang, Feng Shi   +9 more
wiley   +1 more source

Use of existing data for public health planning: a study of the prevalence of hepatitis B surface antigen and core antibody in Al Ain Medical District, United Arab Emirates

Bulletin of the World Health Organization, 2000
INTRODUCTION: Hepatitis B is of major public health importance. Accurate information on its occurrence, with particular reference to the prevalence of immunity and chronic infection (marked by the presence of hepatitis B core antibody and surface antigen,
A. Al-Owais, K. Al-Suwaidi, N. Amiri, A.O. Carter, M.M Hossain, M.M. Sheek-Hussein   +5 more
doaj  

Endemic hepatitis b and c virus infection in a brazilian eastern amazon region

Arquivos de Gastroenterologia, 2010
CONTEXT: Hepatitis B and hepatitis C infection has been an important cause of morbidity and mortality around the world. However there are few investigations regarding the prevalence and possible risk factors for these diseases in Brazil, particularly in ...
Marcelo El Khouri, Quirino Cordeiro, Diogo Arantes Behling Pereira da Luz, Leandro Savoy Duarte, Mônica Elinor Alves Gama, Carlos Eduardo Pereira Corbett   +5 more
doaj   +1 more source