Results 91 to 100 of about 475,040 (341)

Examination of the Polypeptides of Hepatitis B Surface Antigen

Journal of General Virology, 1976
When the polypeptides of hepatitis B surface antigen were examined by SDS-polyacrylamide gel electrophoresis under a variety of conditions, anomalous results were found to be due to (i) variable and at times incomplete dissociation of polypeptides after boiling with 1% SDS and reducing agent, (ii) reaggregation of solubilized material under certain ...
Patricia Mackay, C. J. Burrell
openaire   +3 more sources

Immunosuppressive JAG2+ tumor‐associated neutrophils hamper PD‐1 blockade response in ovarian cancer by mediating the differentiation of effector regulatory T cells

Cancer Communications, EarlyView.
Abstract Background Tumor‐associated neutrophils (TANs) play a critical role in modulating immune responses and exhibit significant heterogeneity. Our previous study demonstrated that jagged canonical Notch ligand 2 (JAG2)+ TANs were associated with an immunosuppressive microenvironment in high‐grade serous ovarian cancer (HGSOC), but the underlying ...
Chenyang Wang, Moran Yang, Yujing Zhong, Kankan Cao, Xueling Wang, Chen Zhang, Yiying Wang, Mengdi He, Jiaqi Lu, Guodong Zhang, Yan Huang, Haiou Liu   +11 more
wiley   +1 more source

Seroprevalence of Hepatitis-B Virus and Evaluation of DNA Extraction Methods from Dried Blood Spot on Filter Paper for Molecular Testing in Kaduna State, Nigeria

Sokoto Journal of Medical Laboratory Science, 2019
Hepatitis B is a potentially life-threatening disease caused by hepatitis B virus. This study was a cross sectional and included a total of 300 paired blood samples collected in tube and on filter paper from students from three secondary schools located ...
Mohammed Ibrahim Tahir * , Ahmed Babangida Suleiman and Abdurrahman El-Fulaty Ahmad
doaj  

Association of oral lichen planus with hepatitis C virus, surface antigen of hepatitis B virus, and diabetes: A clinical and biochemical study

Journal of Indian Academy of Oral Medicine and Radiology, 2016
Background: Oral lichen planus is an inflammatory mucocutaneous disease commonly encountered in the dental clinic. The etiology of oral lichen planus is still unknown.
Pavani Donempudi, Harsha Bhayya, Venkateswarlu Meduri, Geetha Paramkusam, Avinash M L Tejasvi   +4 more
doaj   +1 more source

Discrimination of Membrane Antigen Affinity by B cells Requires Dominance of Kinetic Proofreading over Serial Triggering [PDF]

arXiv, 2010
B cells receptor (BCR) signaling in response to membrane-bound antigen increases with antigen affinity, a process known as affinity discrimination. We use computational modeling to show that B cell affinity discrimination requires that kinetic proofreading predominate over serial engagement.
arxiv  

A biosensor based on magnetoelastic waves for detection of antibodies in human plasma for COVID-19 serodiagnosis [PDF]

Biosensors and Bioelectronics (2024) 116456
The study proposes a new efficient wireless biosensor based on magnetoelastic waves for the detection of antibodies in human plasma, aiming at the serological diagnosis of COVID-19. The biosensor was functionalized with the N antigen - nucleocapsid phosphoprotein of the SARS-CoV-2 virus. Validation analyses, by sodium dodecyl-sulfate polyacrylamide gel
arxiv   +1 more source

Novel molecular mechanisms of immune evasion in hepatocellular carcinoma: NSUN2‐mediated increase of SOAT2 RNA methylation

Cancer Communications, EarlyView.
Abstract Background Hepatocellular carcinoma (HCC) is a deadly malignancy known for its ability to evade immune surveillance. NOP2/Sun RNA methyltransferase family member 2 (NSUN2), an RNA methyltransferase involved in carcinogenesis, has been associated with immune evasion and energy metabolism reprogramming.
Jinhua Jiang, Feng Liu, Dan Cui, Caixia Xu, Jiachang Chi, Tinghua Yan, Fang Guo   +6 more
wiley   +1 more source

Detection of Hepatitis B Virus Antigens in Paraffin-embedded Liver Specimens from the Amazon Region, Brazil

Memorias do Instituto Oswaldo Cruz, 2002
Hepatic viscerotomy of paraffin-preserved old specimens, collected in the period from 1934 to 1967, were analyzed by immunohistochemical assays to detect hepatitis B, hepatitis D, dengue and yellow fever virus antigens. The material belongs to the Yellow
Simonetti SRR, Schatzmayr HG, Barth OM, Simonetti JP   +3 more
doaj  

Promising Prodiginins Biological Activities

Chemistry &Biodiversity, EarlyView.
ABSTRACT Prodiginins are a large family of at least 34 pyrrolic compounds, including the well‐studied red pigment prodigiosin. Prodiginins are produced by several microorganisms displaying broad biological activities, including antimicrobial, antiviral, antiparasitic, antiproliferative, and immunosuppressive activities.
María F. Ladetto, Melisa E. Gantner, Boris E. Rodenak‐Kladniew, Santiago Rodriguez, María L. Cuestas, Alan Talevi, Guillermo R. Castro   +6 more
wiley   +1 more source

Seroprevalence for Hepatitis E and Other Viral Hepatitides among Diverse Populations, Malawi

Emerging Infectious Diseases, 2015
Data on prevalence of hepatitis E virus (HEV) in Malawi is limited. We tested blood samples from HIV-uninfected and -infected populations of women and men enrolled in research studies in Malawi during 1989–2008 to determine the seroprevalence of HEV ...
Taha E. Taha, Laura K. Rusie, Alain Labrique, Mulinda Nyirenda, Dean Soko, Melvin Kamanga, Johnstone Kumwenda, Homayoon Farazadegan, Kenrad Nelson, Newton Kumwenda   +9 more
doaj   +1 more source