Results 101 to 110 of about 475,040 (341)
Harnessing Viral Proteases for Cellular and Molecular Engineering
Chemistry–Methods, EarlyView.Engineered viral proteases (VIPs) provide programmable control of protein function with high specificity and low toxicity. Integrated with chemogenetic and optogenetic modules, these VIP systems enable logic gate manipulation for targeted regulation of cell signaling, gene expression, protein secretion, and degradation, thereby offering versatile ...
Mingguang Cui +2 more
wiley +1 more source
Clinical Pharmacology in Drug Development, EarlyView.Abstract Valemetostat tosylate (valemetostat) is a dual inhibitor of enhancer of zeste homolog (EZH) 2 and EZH1, approved in Japan for the treatment of relapsed/refractory peripheral T‐cell lymphoma and adult T‐cell leukemia/lymphoma. This Phase I, open‐label study evaluated the pharmacokinetics and safety of a single 50‐mg oral dose of valemetostat in
Masaya Tachibana +8 more
wiley +1 more source
Hepatitis B surface antigen in homosexuals. [PDF]
Sexually Transmitted Infections, 1978 M H Hambling, M A Waugh
openaire +3 more sources
Vertical transmission of hepatitis B surface antigen in carrier mothers in two west London hospitals. [PDF]
, 1979 D Woo +5 more
openalex +1 more source
Cytometry Part A, EarlyView.ABSTRACT This 36‐color flow cytometry panel is designed to characterize multiple lymphocyte compartments, with a focus on T cells, their memory subpopulations, and immune checkpoints in human whole blood samples. In clinical settings, the amount of blood available from patients for scientific research is often limited.
Marie‐Theres Thieme‐Ehlert +3 more
wiley +1 more source
Electrochemical sensing strategies for on‐site testing of pathogenic nucleic acids
Electrochemical Science Advances, EarlyView.Abstract Rapid and reliable on‐site pathogen testing is crucial for diagnosing and managing human health. Nucleic acids (NAs) containing genetic information are valuable target molecules for pathogen testing, and sensitive and rapid detection of NAs using electrochemical approaches has been intensively investigated.
Yusuke Kanno +4 more
wiley +1 more source
Multi-point Infection Dynamics of Hepatitis B in the Presence of Sub-Viral Particles [PDF]
arXivHepatitis B virus (HBV) is considered as etiological agent of the lethal liver disease hepatitis B. Globally, hepatitis B is recognized as one of the prevailing infectious diseases with a significant impact on human health. In spite of being non-infectious in nature, sub-viral particles (SVPs) , composed with mainly viral surface proteins, play ...
arxiv
Exploring the Potential and Advancements of Circular RNA Therapeutics
Exploration, EarlyView.Given the remarkable advantages in terms of stability, sustained expression profile, safety, wide range of druggable targets, scalable and cost‐effective manufacturing capabilities, circRNA is currently undergoing intensive investigation for various therapeutic applications such as vaccines, protein replacement, genetic disease treatment, gene therapy,
Lei Wang +6 more
wiley +1 more source
Quantitative Serum HBsAg and M2BPGi Levels in Patients with Chronic Hepatitis D
Central Asian Journal of Medical Sciences, 2016 Objectives: Quantification of serum HBsAg has several clinical significances such as acting as a biomarker for the hepatitis D virus (HDV)-RNA level and necroinflammatory activity in HDV infection.
Sarantuya Gidaagaya +6 more
doaj +1 more source
Antigenicity of hepatitis B surface antigen proteins reconstituted with phospholipids
Biochimica et Biophysica Acta (BBA) - Biomembranes, 1995 Hepatitis B surface antigen (HBsAg) has been reconstituted with different phospholipid classes. All epitopes defined by a panel of monoclonal antibodies which recognize both group- and subtype-specific antigenic determinants showed specificity for acidic phospholipids.
Darrell L. Peterson +3 more
openaire +3 more sources