Results 81 to 90 of about 475,040 (341)

Hepatitis Delta Virus: A Peculiar Virus

open access: yesAdvances in Virology, 2013
The hepatitis delta virus (HDV) is distributed worldwide and related to the most severe form of viral hepatitis. HDV is a satellite RNA virus dependent on hepatitis B surface antigens to assemble its envelope and thus form new virions and propagate ...
Carolina Alves   +2 more
doaj   +1 more source

Mathematical Model and Analysis of Transmission Dynamics of Hepatitis B Virus [PDF]

open access: yesarXiv, 2017
Hepatitis B is a potentially life-threatening liver infection caused by the hepatitis B virus (HBV). In this paper, the transmission dynamics of hepatitis B is formulated with a mathematical model with considerations of different classes of individuals, namely immunized, susceptible, latent,infected and recovered class.
arxiv  

Roadmap to Nanomedical Applications: Nanotoxicology and In Vitro Guidelines for Lanthanide‐Doped Luminescence Nanothermometers

open access: yesAdvanced NanoBiomed Research, EarlyView.
Lanthanide‐based luminescence nanothermometry holds multifaceted potential for nanomedical applications, yet despite significant research advances, clinical translation of the engineered nanomaterials is still controversial and widely disputed. This is related to crucial nanotoxicological aspects that must be addressed at the preclinical level ...
Simona Premcheska   +2 more
wiley   +1 more source

Chitosan Plus Compound 48/80: Formulation and Preliminary Evaluation as a Hepatitis B Vaccine Adjuvant

open access: yesPharmaceutics, 2019
Current vaccine research is mostly based on subunit antigens. Despite the better toxicity profile of these antigens they are often poorly immunogenic, so adjuvant association has been explored as a strategy to obtain a potent vaccine formulation ...
Dulce Bento   +4 more
doaj   +1 more source

Oral paltusotine, a nonpeptide selective somatostatin receptor 2 agonist: Mass balance, absolute bioavailability and metabolism in healthy participants

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract Aims Paltusotine is a novel, nonpeptide, selective somatostatin receptor 2 agonist in development for the treatment of acromegaly and carcinoid syndrome. This study investigated the mass balance, routes of excretion, absolute bioavailability and metabolite profile of orally administered paltusotine.
Rosa Luo   +6 more
wiley   +1 more source

The contribution of extracellular RNA and its derived biomaterials in disease management

open access: yesBMEMat, EarlyView.
The implications of exRNA's biological function and the structural uniqueness of RNA help establish a close connection between RNA, material, and modern medicine. Abstract The RNA found in the circular system is known as extracellular RNA (exRNA). This kind of RNA has been found to play a biological role similar to that of a messenger. They can be used
Yu Wei   +8 more
wiley   +1 more source

Liver organoids: From 3D printing to biomedical applications

open access: yesBMEMat, EarlyView.
A comprehensive review on liver organoids culture techniques from 3D printing to organ‐on‐chip, as well as focusing on challenges and perspectives for advancement liver organoids in various future applications. Abstract The liver is an immune organ, especially an immune tolerance organ.
Ying Shi   +4 more
wiley   +1 more source

Use of existing data for public health planning: a study of the prevalence of hepatitis B surface antigen and core antibody in Al Ain Medical District, United Arab Emirates

open access: yesBulletin of the World Health Organization, 2000
INTRODUCTION: Hepatitis B is of major public health importance. Accurate information on its occurrence, with particular reference to the prevalence of immunity and chronic infection (marked by the presence of hepatitis B core antibody and surface antigen,
A. Al-Owais   +5 more
doaj  

Anti-Hepatitis B Virus Activity of Esculetin from Microsorium fortunei In Vitro and In Vivo

open access: yesMolecules, 2019
Coumarins are widely present in a variety of plants and have a variety of pharmacological activities. In this study, we isolated a coumarin compound from Microsorium fortunei (Moore) Ching; the compound was identified as esculetin by hydrogen and carbon ...
Si-Xin Huang   +9 more
doaj   +1 more source

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