Results 121 to 130 of about 419,079 (384)

Fertility and Early Embryonic Development Toxicity of hzVSF‐v13 in Sprague–Dawley Rats

Journal of Applied Toxicology, EarlyView.
ABSTRACT Humanized virus suppressing factor–variant 13 (hzVSF‐v13), a monoclonal IgG4 antibody, is a potential therapeutic candidate for COVID‐19. Although fertility and embryonic developmental toxicity studies are crucial for the safety evaluation of new drugs, the toxicological profile of hzVSF‐v13 remains unexplored.
Ji‐Seong Jeong, Sang‐Yun Kim, Jinsoo Lee, Seung‐Jin Lee, Onju Ham, Woojin Kim, Wan‐Jung Im, Sungman Park, Kyong‐Cheol Ko, Jong‐Choon Kim, Yong‐Bum Kim   +10 more
wiley   +1 more source

[Hepatitis B vaccines-history, achievements, challenges, and perspectives]. [PDF]

Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz, 2022
Gerlich WH.
europepmc   +1 more source

A controlled clinical trial of the efficacy of the hepatitis B vaccine (heptavax B): A final report [PDF]

, 1981
W. Szmuness, Cladd E. Stevens, Edith Zang, Edward J. Harley, Aaron Kellner   +4 more
openalex   +1 more source

Recent Utilization of Pediatric Extrapolation and Modeling and Simulation Approaches in Pediatric Drug Development in Japan

The Journal of Clinical Pharmacology, EarlyView.
Abstract In Japan, the percentage of approved drugs with pediatric indications increased to 30% in 2010‐2015, but no further increase was observed through 2020. The Ministry of Health, Labor, and Welfare in Japan presented draft future directions to promote pediatric drug development, where the modeling and simulation (M&S) approach was introduced as a
Akinori Nakashima, Akihide Tsujimoto, Masako Saito, Jun Takeda, Makiko Natori, Satoshi Shoji   +5 more
wiley   +1 more source

Factors associated with complete vaccination schedules against hepatitis B in primary health care

Rev Rene
Objective: to analyze factors associated with full hepatitis B vaccination in primary health care workers. Methods: cross-sectional research involving primary care health workers through the application of an instrument, verification of vaccination ...
Cecília Natielly da Silva Gomes, Danielle Nedson Rodrigues de Mâcedo, Luany do Nascimento Feitosa, Emanoelle Fernandes Silva, Maria Laura de Lima Brito Magalhães, Breno Dias de Oliveira Martins, Rosilane de Lima Brito Magalhães   +6 more
doaj   +1 more source

Mitogen-activated protein kinase eight polymorphisms are associated with immune responsiveness to HBV vaccinations in infants of HBsAg(+)/HBeAg(−) mothers

BMC Infectious Diseases, 2018
Background Infants born to hepatitis B surface antigen (HBsAg) positive mothers are at a higher risk for Hepatitis B virus (HBV) infection. Host genetic background plays an important role in determining the strength of immune response to vaccination.
Meng Zhuo Cao, Yan Hua Wu, Si Min Wen, Yu Chen Pan, Chong Wang, Fei Kong, Chuan Wang, Jun Qi Niu, Jie Li, Jing Jiang   +9 more
doaj   +1 more source

Importance of HBsAg recognition by HLA molecules as revealed by responsiveness to different hepatitis B vaccines. [PDF]

Sci Rep, 2021
Nishida N, Sugiyama M, Ohashi J, Kawai Y, Khor SS, Nishina S, Yamasaki K, Yazaki H, Okudera K, Tamori A, Eguchi Y, Sakai A, Kakisaka K, Sawai H, Tsuchiura T, Ishikawa M, Hino K, Sumazaki R, Takikawa Y, Kanda T, Yokosuka O, Yatsuhashi H, Tokunaga K, Mizokami M.   +23 more
europepmc   +1 more source

The Effectiveness of California Assembly Bill 2109: Personal Belief Exemptions for Kindergarten Immunizations [PDF]

, 2016
The numbers of vaccine preventable diseases (VPDs) in the United States has declined with the development, administration, and effectiveness of vaccines during the 1970s and 1980s.
Goishi-Bessey, Lilli Shizuka
core   +1 more source

Bee products as alternatives in the treatment of viral infections

Journal of the Science of Food and Agriculture, EarlyView.
Abstract Medicines used in the treatment of viral infections usually reduce symptoms. There is a need to develop drugs that inhibit the viruses and do not merely relieve the symptoms. Natural bee products possess many pharmacological properties and are widely used in folk medicine. There are many studies on the antibacterial effects of bee products but
Michał Otręba, Łukasz Marek, Jerzy Stojko, Anna Rzepecka‐Stojko   +3 more
wiley   +1 more source

Potential Association between Shift Work and Serologic Response to Hepatitis B Vaccination among Manufacturing Workers in Republic of Korea

Vaccines
(1) Background: Shift work can affect physical health and the immune system by altering the body’s circadian rhythms. This study investigated the factors associated with the hepatitis B virus (HBV) vaccination response in manufacturing workers ...
Si-Ho Kim, Chang-Ho Chae
doaj   +1 more source