Results 291 to 300 of about 419,079 (384)

Primary Progressive Multiple Sclerosis: New Therapeutic Approaches

Neuropsychopharmacology Reports, Volume 45, Issue 3, September 2025.
Primary progressive MS affects 10%–15% of MS patients, causing irreversible neurological impairment. Drugs like ocrelizumab show promise, while high‐dose biotin, simvastatin, and coenzyme Q10 are under investigation. Gene therapy and stem cell treatments also show potential.
Morteza Rajabi, Sajjad Shafaeibajestan, Sevda Asadpour, Ghazal Alyari, Niloofar Taei, Moein Kohkalani, Ramin Raoufinia, Hamed Afarande, Ehsan Saburi   +8 more
wiley   +1 more source

Trends in pediatric vaccination coverage in Italy from 2000 to 2023. [PDF]

Eur J Public Health
Villani L, Causio FA, Savoia C, Pastorino R, Ricciardi W, Boccia S, de Waure C.   +6 more
europepmc   +1 more source

Comparative analysis of the extent of protein–protein interactions in icosahedral viral capsids

Protein Science, Volume 34, Issue 9, September 2025.
Abstract Nonenveloped viruses package, carry, and deliver their genomes to the targeted cells using protein shells known as capsids. The viral capsids come in different shapes and sizes, most exhibiting helical or icosahedral symmetries. Here, we analyzed 634 icosahedral capsids at high resolution (<4 Å) from 39 virus families with T‐numbers ranging ...
Noah J. Zimmerman, Oscar Rojas Labra, Vijay S. Reddy   +2 more
wiley   +1 more source

Achieving immunization milestones: Insights from Oman's national coverage survey. [PDF]

PLoS One
Al-Rawahi B, K P P, Al-Farsi N, Al-Shaibi M, Al-Jahwari A, Al-Abri B, Al-Abri S.   +6 more
europepmc   +1 more source

Retrospective Cross‐Sectional Study of Occupational Infection Risk With Zoonotic Pathogens in Austrian Veterinary Practitioners in the Year 2022

Veterinary Medicine and Science, Volume 11, Issue 5, September 2025.
• Vaccination rates against rabies and TBEV and accordingly the respective seroprevalence rates exceed 90% among Austrian veterinary practitioners. • The prevalence of antibodies against HEV and the colonisation with MRSA increases with the age of the study participants from 6.2%/6.2% in the youngest age group to 23.3%/21.9% in the oldest group. • MRSA
Tatjana Sattler, Bernhard Benka, Irene Zimpernik, Sarah Pürrer, Karoline Waldner, Georg G. Duscher, Agnes Kuffer‐Rosewick, Jasmin Fertey, Sebastian Ulbert, Friedrich Schmoll   +9 more
wiley   +1 more source

Understanding the Enigmatic Dance of Immune‐Mediated Viral Infections and Their Pathogenetic Mechanisms

Veterinary Medicine and Science, Volume 11, Issue 5, September 2025.
This graphical representation illustrates the multifaceted nature of the immune response in viral infections, demonstrating both its protective and potentially harmful aspects. While a properly regulated immune reaction facilitates viral clearance and promotes general recovery, an overly robust or misdirected response—exemplified by Type III or Type IV
Muhammed Cesim Karabulut, Tuba Çiğdem Oğuzoğlu   +1 more
wiley   +1 more source

Vaccine Adjuvants in the Immunocompromised Host: Science, Safety, and Efficacy. [PDF]

Transpl Infect Dis
Hayek H, Hasan L, Amarin JZ, Qwaider YZ, Hamdan O, Rezende W, Dee KC, Chappell JD, Halasa NB.   +8 more
europepmc   +1 more source

Molecular characterization of positive-stranded RNA viruses [PDF]

, 1993
Conzelmann, Karl-Klaus, Kaaden, Oskar-Rüger, Meyers, G., Rümenapf, T., Stark, R., Tautz, N., Thiel, Heinz-Jürgen, Unger, G.   +7 more
core  

The ‘Informed Matter’ of Gay and Bisexual Men's (Potential) Use of HIV Antiretrovirals to Prevent COVID‐19

Sociology of Health &Illness, Volume 47, Issue 7, September 2025.
ABSTRACT In 2020, there were reports that HIV antiretrovirals, specifically the combination tenofovir disoproxil fumarate and emtricitabine (TDF/FTC), had therapeutic potential for COVID‐19. In the context of scant empirical evidence at the time to confirm such an effect, we sought to understand the ways that gay and bisexual men (GBM) made sense of ...
Daniel Storer, Dean Murphy, Niamh Stephenson, Garrett Prestage, Mohamed A. Hammoud   +4 more
wiley   +1 more source