Fertility and Early Embryonic Development Toxicity of hzVSF‐v13 in Sprague–Dawley Rats
Journal of Applied Toxicology, EarlyView.ABSTRACT Humanized virus suppressing factor–variant 13 (hzVSF‐v13), a monoclonal IgG4 antibody, is a potential therapeutic candidate for COVID‐19. Although fertility and embryonic developmental toxicity studies are crucial for the safety evaluation of new drugs, the toxicological profile of hzVSF‐v13 remains unexplored.
Ji‐Seong Jeong +10 more
wiley +1 more source
The Role of Viral and Bacterial Infections in the Etiology of Behçet's Disease
Journal of Clinical Laboratory Analysis, EarlyView.Bacterial and viral pathogens may play a key role in Behçet's disease (BD) pathogenesis by triggering autoimmunity, molecular mimicry, or microbiome disruption. These infectious agents could initiate inflammatory pathways, contributing to BD's diverse clinical manifestations.
Mohsen Moghoofei +4 more
wiley +1 more source
Clinical progress note: Hepatitis A virus
Journal of Hospital Medicine, EarlyView.Abstract Despite a decline in hepatitis A virus (HAV) incidence following vaccine introduction, HAV remains a public health concern in the United States. Recent multi‐state outbreaks have demonstrated that HAV can re‐emerge and highlight inequities in vaccine coverage or access, outbreak response, and in those with social or health risk factors ...
James M. McCluskey III +2 more
wiley +1 more source
Knowledge of Hepatitis B Vaccine among Operating Room Personnel in Nigeria and Their Vaccination Status [PDF]
, 2011 Emeka B Kesieme +5 more
openalex +1 more source
The Co-Administration of COVID-19 and Hepatitis B Vaccines, Should Safety Be a Concern? [PDF]
Infect Chemother, 2022 Alrashdan MS, El-Kishawi M, Al Kawas S.
europepmc +1 more source
IKAROS Associated Immunodeficiency and Thrombotic Thrombocytopenic Purpura
Pediatric Blood &Cancer, EarlyView.ABSTRACT Pathogenic variants in IKZF1 (IKAROS) are linked to immunodeficiency, malignancy, and immune dysregulation. We describe a family with a rare IKZF1 variant presenting with humoral immunodeficiency and thrombotic thrombocytopenic purpura (TTP). A non‐consanguineous family was clinically monitored; clinical, immunological, and genetic data (exome
Ilia Spivak +7 more
wiley +1 more source
Supra and subgingival application of antiseptics or antibiotics during periodontal therapy
Periodontology 2000, EarlyView., 2023 Abstract Periodontal diseases (gingivitis and periodontitis) are characterized by inflammatory processes which arise as a result of disruption of the balance in the oral ecosystem. According to the current S3 level clinical practice guidelines, therapy of patients with periodontitis involves a stepwise approach that includes the control of the patient ...
Elena Figuero +5 more
wiley +1 more source
Economic Impact of Switching From Partially Combined Vaccine “Pentaxim ® and Hepatitis B” to Fully Combined Vaccine “Hexaxim ® ” in The Malaysian National Immunization Program [PDF]
, 2021 Syed Mohamed Aljunid +5 more
openalex +1 more source
Common Genetic Variants of Response to Hepatitis B Vaccines Correlate with Risks of Chronic Infection of Hepatitis B Virus: A Community-Based Case-Control Study. [PDF]
Int J Mol Sci, 2023 Wu TW, Chou CL, Chen CF, Wang LY.
europepmc +1 more source
The Cinderella tree, Quillaja saponaria – A soap story
PLANTS, PEOPLE, PLANET, EarlyView.Our current understanding of plants has been shaped by the entwining of different cultures. The Chilean soapbark tree, traditionally valued as a source of natural soap, was shown by serendipitous research in France in the 1900s to produce compounds that can boost the immune response to vaccines.
Anne Osbourn
wiley +1 more source