Problems of the Current Vaccination Strategy against Hepatitis B
Accumulation of escape mutants of hepatitis B virus (HBV) occur in the many countries at the conditions of wide-scale vaccination against hepatitis B, especially among vaccinated children.
M. V. Konopleva+3 more
doaj +1 more source
Predictions of the emergence of vaccine-resistant hepatitis B in The Gambia using a mathematical model [PDF]
Vaccine escape variants of hepatitis B virus (HBV) have been identified world-wide. A mathematical model of HBV transmission is used to investigate the potential pattern of emergence of such variants.
Carman, W. (William)+2 more
core +2 more sources
Recombinant Flag-tagged E1E2 glycoproteins from three hepatitis C virus genotypes are biologically functional and elicit cross-reactive neutralizing antibodies in mice [PDF]
Hepatitis C virus (HCV) is a globally disseminated human pathogen for which no vaccine is currently available. HCV is highly diverse genetically and can be classified into 7 genotypes and multiple sub-types. Due to this antigenic variation, the induction
Bieńkowska-Szewczyk, Krystyna+5 more
core +1 more source
B cells and systemic sclerosis interstitial lung disease
Interstitial lung disease is an important complication of systemic sclerosis (SSc‐ILD) with high mortality and morbidity. Recent clinical studies in SSc‐ILD have led to FDA‐approved therapies in SSc‐ILD. Importantly, evidence from these studies has been extrapolated to guide management of interstitial lung diseases of other systemic autoimmune ...
Nina Goldman+2 more
wiley +1 more source
Background/Objectives: In chronic hepatitis B infection (CHB), the hepatitis B surface antigen (HBsAg) continuously exhausts the hepatitis B surface antibody (HBsAb), which leads to the formation of immune tolerance.
Shang Liu+10 more
doaj +1 more source
Pharmacists in a number of countries are being trained in the administration of injections with the aim of improving access and adherence to vaccinations.
Sherilyn K D Houle, Dean T Eurich
doaj +1 more source
Modern View on the Problem of Choosing a Vaccine against Hepatitis B
The problem of the discrepancy between serotypes of the circulating strains of hepatitis B virus and serotype of the HBsAg in the vaccine is discussed. The results of published scientific studies show that hepatitis B vaccines containing HBsAg serotype ...
V. P. Chulanov+6 more
doaj +1 more source
Harvesting AAV by tangential flow filtration using reverse asymmetric membranes
Abstract Efficient bioreactor clarification for harvesting virus particles is often challenging. Tangential flow filtration is attractive as it can be easily adapted for batch and perfusion operations. Here the feasibility of using reverse asymmetric hollow fiber membranes, where the more open support structure faces the feed stream, has been ...
Xiaolei Hao+5 more
wiley +1 more source
Vaccination in the setting of sexually transmitted infections consultation
Sexually transmitted infections (STIs) are a significant public health concern across the globe. Vaccines have played a crucial role in mitigating the burden of infectious diseases and are the most effective candidates for preventing STIs.
Lanyu Sun+4 more
doaj
Factors Associated with Immunization Opinion Leadership among Men Who Have Sex with Men in Los Angeles, California [PDF]
We sought to identify the characteristics of men who have sex with men (MSM) who are opinion leaders on immunization issues and to identify potential opportunities to leverage their influence for vaccine promotion within MSM communities.
Bednarczyk, Robert+9 more
core +3 more sources