Results 181 to 190 of about 802,486 (287)

Immunology of hepatitis B virus and hepatitis C virus infection

Nature reviews. Immunology, 2005
B. Rehermann, M. Nascimbeni
semanticscholar   +1 more source

Harnessing Viral Proteases for Cellular and Molecular Engineering

Chemistry–Methods, EarlyView.
Engineered viral proteases (VIPs) provide programmable control of protein function with high specificity and low toxicity. Integrated with chemogenetic and optogenetic modules, these VIP systems enable logic gate manipulation for targeted regulation of cell signaling, gene expression, protein secretion, and degradation, thereby offering versatile ...
Mingguang Cui, Tien‐Hung Lan, Yubin Zhou   +2 more
wiley   +1 more source

Wnt/β-Catenin Signaling Regulates Hepatitis B Virus cccDNA Levels. [PDF]

Int J Mol Sci
Ishida A, Iwabuchi S, Li YY, Murai K, Shirasaki T, Kuroki K, Shimakami T, Nio K, Kawaguchi K, Imafuku T, Ito S, Yamashita T, Kaneko S, Yanagawa H, Matsushima K, Honda M, Hashimoto S.   +16 more
europepmc   +1 more source

Changes of hepatitis B virus DNA in liver and serum caused by recombinant leukocyte interferon treatment: Analysis of intrahepatic replicative hepatitis B virus DNA [PDF]

, 1985
Osamu Yokosuka, Masao Omata, Fumio Imazeki, Kunio Okuda, Jesse Summers   +4 more
openalex   +1 more source

A serum exosomal microRNA‐based artificial intelligence diagnostic model for highly accurate detection of hepatocellular carcinoma

Cancer Communications, EarlyView.
Jin‐Seong Hwang, Sugi Lee, Gyeonghwa Kim, Hoibin Jeong, Kiyoon Kwon, Eunsun Jung, Yuna Roh, Taesang Son, Hana Lee, Moo‐Seung Lee, Kyoung‐Jin Oh, Hye Won Lee, Yu Rim Lee, Soo Young Park, Won Young Tak, Hyun Seung Ban, Hyun‐Soo Cho, Mi‐Young Son, Jang‐Seong Kim, Keun Hur, Dae‐Soo Kim, Tae‐Su Han   +21 more
wiley   +1 more source

Pharmacokinetics, Safety, and Skin Irritation and Sensitization Potential of Clascoterone Cream in Early‐Phase Clinical Study Participants

Clinical Pharmacology in Drug Development, EarlyView.
Abstract Clascoterone is an androgen receptor inhibitor approved for the treatment of acne vulgaris in patients 12 years of age and older. Here, we report results of 5 phase 1 studies that assessed the pharmacokinetics (PK), safety, and skin irritation and sensitization potential of clascoterone cream 1% in healthy participants and patients with acne ...
Andrea Francesco Daniele Di Stefano, Milko Massimiliano Radicioni, Gerhard Garhöfer, Martina Cartwright, Markus Müller, Iris Kopeloff, Luigi Moro, Nicholas Squittieri, Alessandro Mazzetti   +8 more
wiley   +1 more source

Syndecan 2 proteoglycan serves as a hepatitis B virus cell attachment receptor. [PDF]

J Virol
Tripathi SK, Li Y, Luo G.
europepmc   +1 more source

Origins and Evolution of Hepatitis B Virus and Hepatitis D Virus.

Cold Spring Harbor Perspectives in Medicine, 2016
M. Littlejohn, S. Locarnini, L. Yuen
semanticscholar   +1 more source

Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Food Effect of Bexicaserin in Healthy Participants: A First‐in‐Human Randomized, Double‐Blind, Placebo‐Controlled Single Ascending Dose Escalation Phase 1 Study

Clinical Pharmacology in Drug Development, EarlyView.
Abstract Bexicaserin (LP352) is a selective 5‐hydroxytryptamine 2C (5‐HT2C) superagonist in development for the treatment of seizures in developmental and epileptic encephalopathies (DEEs). This double‐blind, placebo‐controlled, single ascending dose (SAD) Phase 1 study aimed to assess the safety, tolerability, and pharmacokinetic (PK) and ...
Rosa Chan, Chad Orevillo, Gale O'Connell, Dewey McLin, Shikha Polega, Nuggehally R Srinivas, Randall Kaye   +6 more
wiley   +1 more source

Surface Gene Mutations of Hepatitis B Virus and Related Pathogenic Mechanisms: A Narrative Review. [PDF]

Viruses
Yan T, Zhang Y, Zhou H, Jiang N, Wang X, Yan W, Yin J.   +6 more
europepmc   +1 more source